Endothelin News and Research

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Endothelins are proteins that constrict blood vessels and raise blood pressure. They are normally kept in balance by other mechanisms, but when they are over-expressed, they contribute to high blood pressure (hypertension) and heart disease.
Actelion, Auxilium partner to develop and commercialize XIAFLEX

Actelion, Auxilium partner to develop and commercialize XIAFLEX

Clazosentan drug shows promise against TBI in rats

Clazosentan drug shows promise against TBI in rats

Children with SDB may have better QOL after adenotonsillectomy

Children with SDB may have better QOL after adenotonsillectomy

Benefits of vitamin D-fortified yoghurt drink for people with diabetes

Benefits of vitamin D-fortified yoghurt drink for people with diabetes

Top-line data from Spectrum's SPI-1620 Phase 1 combination study on carcinoma

Top-line data from Spectrum's SPI-1620 Phase 1 combination study on carcinoma

United Therapeutics completes treprostinil diethanolamine Phase 3 trial in PAH

United Therapeutics completes treprostinil diethanolamine Phase 3 trial in PAH

Roche RTCA HT Instrument allows fully-automated impedance screens for GPCRs

Roche RTCA HT Instrument allows fully-automated impedance screens for GPCRs

Actelion awards grants to 2011 ENTELLIGENCE young investigators for research in pulmonary arterial hypertension

Actelion awards grants to 2011 ENTELLIGENCE young investigators for research in pulmonary arterial hypertension

United Therapeutics completes oral treprostinil Phase 3 trial on pulmonary arterial hypertension

United Therapeutics completes oral treprostinil Phase 3 trial on pulmonary arterial hypertension

New study finds no significant benefit of bosentan against IPF

New study finds no significant benefit of bosentan against IPF

United Therapeutics completes enrollment in FREEDOM-C(2) UT-15C study in pulmonary arterial hypertension

United Therapeutics completes enrollment in FREEDOM-C(2) UT-15C study in pulmonary arterial hypertension

FDA approves change to prescribing information for Gilead Sciences' Letairis

FDA approves change to prescribing information for Gilead Sciences' Letairis

Monthly liver enzyme tests not required for PAH patients taking Letairis tablets: FDA

Monthly liver enzyme tests not required for PAH patients taking Letairis tablets: FDA

Combination therapy may reduce albuminuria in patients with type 2 diabetes: Study

Combination therapy may reduce albuminuria in patients with type 2 diabetes: Study

Certain drugs may block tumor host interactions but do not destroy cancer cells

Certain drugs may block tumor host interactions but do not destroy cancer cells

Scientists investigate new class of drugs for treating kidney failure

Scientists investigate new class of drugs for treating kidney failure

Study examines link between insufficient sleep and blood pressure among pregnant women

Study examines link between insufficient sleep and blood pressure among pregnant women

Study on kidneys may help to treat high blood pressure

Study on kidneys may help to treat high blood pressure

FDA approves brand name VELETRI for Actelion's epoprostenol for injection therapy

FDA approves brand name VELETRI for Actelion's epoprostenol for injection therapy

REVEAL risk score calculator provides innovative approach to better understand PAH

REVEAL risk score calculator provides innovative approach to better understand PAH