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Study reveals hidden inactive form of p38a protein

p38a protein, a key enzyme in the regulation of various cellular functions, plays a crucial role in some diseases, including cancer, chronic inflammation, and neurodegenerative conditions.

19 Dec 2023

UMass Amherst researchers develop novel strategy to outsmart antibiotic-resistant ‘superbugs’

Antibiotic-resistant "superbugs" that can defeat efforts to kill them are an urgent public health crisis, and according to the Centers for Disease Control, more than 2.8 million antibiotic-resistant infections occur each year.

18 Dec 2023

New vaccine strategy targets SARS-CoV-2's stable S2 subunit, offering broad protection against evolving variants

Study presents a new SARS-CoV-2 S2 subunit vaccine that elicits strong antibody responses against various sarbecovirus strains, including challenging variants like XBB.1.5, demonstrating its potential as a broadly effective and stable vaccine option.

18 Dec 2023

Transgenic carrots producing nisin protein show promise as natural food preservatives

Study explores the production of nisin protein in transgenic carrots, demonstrating its potential as a natural preservative effective against bacterial pathogens in food and juices.

18 Dec 2023

Oxidized amino acids signal damaged photosynthesis proteins for repair

Photosynthesis refers to the fundamental biological process of the conversion of light energy into chemical energy by chlorophyll (a green pigment) containing plants.

18 Dec 2023

New discovery could expand the possibilities for medical use of Botox

PSI researchers have discovered a surprising trick that could expand the possibilities for medical use of botulinun toxin A1, better known under the name Botox, as an active agent.

18 Dec 2023

Experimental drug paired with a standard-care medication offers hope for kidney disease patients

In a clinical trial of patients with chronic kidney disease, an experimental drug significantly reduced albuminuria -; albumin in urine, a sign of kidney damage -; for 50% of participants.

15 Dec 2023

Wnt signaling holds promise for tailored immunotherapy in microsatellite-instable colorectal cancer

Colorectal cancer presents with varying clinical characteristics due to tumor heterogeneity. Microsatellite instability (MSI), present in 10%-15% of CRC cases, indicates a different clinical trajectory than microsatellite stable (MSS) patients.

15 Dec 2023

New dry powder aerosol COVID-19 vaccine shows promise against multiple virus strains

Study introduces a novel dry powder aerosol COVID-19 vaccine, showing its effectiveness in inducing strong immune responses and offering protection against various SARS-CoV-2 strains, including Omicron.

15 Dec 2023

IFNγ identified as crucial for reducing pulmonary viral loads in COVID-19, new research shows

The role of type-2 interferon (IFNγ) in antiviral immunity.

14 Dec 2023

Targeting cholesterol metabolism for the treatment of serrated colorectal neoplasms

Hard-to-detect colorectal pre-cancerous lesions known as serrated polyps, and the aggressive tumors that develop from them, depend heavily on the ramped-up production of cholesterol, according to a preclinical study from researchers at Weill Cornell Medicine.

13 Dec 2023

OHSU study sheds light on ubiquitin modification during bacterial infection

New research from Oregon Health & Science University could one day lead to therapies that prevent or treat diseases and infections tied to a protein that's found in all human cells.

12 Dec 2023

Evaluation of immunogenicity-induced DNA vaccines against different SARS-CoV-2 variants

Five DNA vaccine candidates based on different SARS-CoV-2 strains.

12 Dec 2023

SolasCure demonstrates proof-of-concept in Phase lla safety trial of Aurase Wound Gel

SolasCure today announced the results of its proof-of-concept, first-in-human, Phase IIa safety study.

From SolasCure 12 Dec 2023

New optimized vaccine approach targets Hepatitis C virus variability

A method to design vaccines for highly variable viruses like the hepatitis C virus.

12 Dec 2023

Gene therapy shows promise for arrhythmogenic cardiomyopathy

Researchers evaluated the effectiveness of adeno-associated virus (AAV)-mediated Plakophilin 2 (PKP2) delivery in treating arrhythmogenic cardiomyopathy (ACM).

12 Dec 2023

Study reveals new mechanism by which rotavirus induces diarrhea

Rotavirus causes gastroenteritis, a condition that includes diarrhea, deficient nutrient absorption and weight loss. Severe cases result in approximately 128,000 deaths annually in infants and children worldwide.

11 Dec 2023

New SARS-CoV-2 variant JN.1 shows increased transmissibility and immune resistance

A Japanese study published in BioRxiv explores the virological characteristics of the SARS-CoV-2 JN.1 variant, finding it has a higher effective reproductive number and stronger resistance to immunity from other variants, potentially due to the L455S spike protein mutation.

11 Dec 2023

Research uncovers potential treatment target for rare, genetic type of epilepsy

Researchers at the Francis Crick Institute, UCL and MSD have identified a potential treatment target for a genetic type of epilepsy.

11 Dec 2023

MIT scientists develop nanoparticles to reduce inflammation in the brain

Some Covid-19 vaccines safely and effectively used lipid nanoparticles (LNPs) to deliver messenger RNA to cells. A new MIT study shows that different nanoparticles could be used for a potential Alzheimer's disease (AD) therapy.

11 Dec 2023

Enzyme News and Research

Study reveals hidden inactive form of p38a protein

UMass Amherst researchers develop novel strategy to outsmart antibiotic-resistant ‘superbugs’

New vaccine strategy targets SARS-CoV-2's stable S2 subunit, offering broad protection against evolving variants

Transgenic carrots producing nisin protein show promise as natural food preservatives

Oxidized amino acids signal damaged photosynthesis proteins for repair

New discovery could expand the possibilities for medical use of Botox

Experimental drug paired with a standard-care medication offers hope for kidney disease patients

Wnt signaling holds promise for tailored immunotherapy in microsatellite-instable colorectal cancer

New dry powder aerosol COVID-19 vaccine shows promise against multiple virus strains

IFNγ identified as crucial for reducing pulmonary viral loads in COVID-19, new research shows

Targeting cholesterol metabolism for the treatment of serrated colorectal neoplasms

OHSU study sheds light on ubiquitin modification during bacterial infection

Evaluation of immunogenicity-induced DNA vaccines against different SARS-CoV-2 variants

SolasCure demonstrates proof-of-concept in Phase lla safety trial of Aurase Wound Gel

New optimized vaccine approach targets Hepatitis C virus variability

Gene therapy shows promise for arrhythmogenic cardiomyopathy

Study reveals new mechanism by which rotavirus induces diarrhea

New SARS-CoV-2 variant JN.1 shows increased transmissibility and immune resistance

Research uncovers potential treatment target for rare, genetic type of epilepsy

MIT scientists develop nanoparticles to reduce inflammation in the brain

Biochemistry eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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