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Tocotrienol form of vitamin E prevents neural cell death and rescues the brain after stroke injury

Blocking the function of an enzyme in the brain with a specific kind of vitamin E can prevent nerve cells from dying after a stroke, new research suggests.

12 Jan 2010

Amicus Therapeutics presents corporate outlook for 2010 at Annual J.P. Morgan Healthcare Conference

Amicus Therapeutics today outlined the Company's three key strategic priorities and presented a corporate outlook for 2010 at the 28th Annual J.P. Morgan Healthcare Conference.

12 Jan 2010

New findings would allow doctors to tailor drug cocktails for particular viral strains

Chemists at UC San Diego and statisticians at Harvard University have developed a novel way to trace mutations in HIV that lead to drug resistance. Their findings, once expanded to the full range of drugs available to treat the infection, would allow doctors to tailor drug cocktails to the particular strains of the virus found in individual patients.

12 Jan 2010

Cancer drug may provide an effective secondary treatment for gut tumor

A drug that is already an approved therapy for some cancers also might be an effective secondary treatment for a rare tumor of the gastrointestinal tract, according to a team led by researchers from the University of Pittsburgh Cancer Institute (UPCI). The findings, based on experiments using cell cultures, were published in the Jan. 1 issue of Cancer Research.

12 Jan 2010

New therapeutic treatment may provide a potential alternative to bone grafting operation

A study published this week reinforces the potential value of stem cells in repairing major injuries involving the loss of bone structure.

12 Jan 2010

Researchers identify treatment to reduce health problems associated with enzyme defect

An experimental compound repaired a defective alcohol metabolism enzyme that affects an estimated 1 billion people worldwide, according to research supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA).

10 Jan 2010

Research into "chemical chaperone" may lead to new treatments for heart attacks

Researchers at the Indiana University and Stanford University schools of medicine have determined how a "chemical chaperone" does its job in the body, which could lead to a new class of drugs to help reduce the muscle damage caused by heart attacks.

10 Jan 2010

Jiangsu Government grants $1.8M for research and development of hUC-MSC technologies

The Jiangsu Government's Science and Technology Department has announced a $1.8 million grant - the Jiangsu Technological Achievements Transformational Grant - to support the research and development of human umbilical cord mesenchymal stem cell (hUC-MSC) technologies. The grant recipient and administrator, Shenzhen Beike Biotechnology Co., Ltd. (http://www.beikebiotech.com ), is working with Jiangsu University and Nanjing University's Drum Tower Hospital to fulfill the grant's requirements.

9 Jan 2010

Researchers identify key epigenetic mechanism that helps explain cocaine's addictiveness

Researchers have identified a key epigenetic mechanism in the brain that helps explain cocaine's addictiveness, according to research funded by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health.

8 Jan 2010

CSHL scientists explain how initiation of DNA replication is coordinated and controlled by kinase proteins

Scientists at Cold Spring Harbor Laboratory (CSHL) have discovered how a protein long known to be an essential activator of DNA replication actually triggers this process in cells.

8 Jan 2010

Phase 1 clinical trial of SIRT1 inhibitor for the treatment of Huntington’s Disease commenced

Elixir Pharmaceuticals, Inc. announced today that its partner, Siena Biotech S.p.A., has commenced Phase 1 clinical testing of Elixir’s potent, first-in-class SIRT1 (sirtuin-1) inhibitor for the treatment of Huntington’s Disease.

8 Jan 2010

Researchers seek to defeat Alzheimer's disease by modifying mice's immune system

Using laboratory mice that had been bred to have brain changes similar to Alzheimer's disease, scientists were able to reduce two characteristic features of the disease by modifying the mice's immune systems with a special peptide (MOG45D) related to the myelin sheath that insulates nerve cells and nerve fibers. As a result, anti-inflammatory cells were recruited from the blood into the brain, dampening the local inflammatory response.

7 Jan 2010

Authors explain why health care reform initiative should include CER

The current health care reform bills approved by the House and the Senate seek to expand health insurance coverage while containing costs; however, the proposed policy changes are not guaranteed to improve health for individuals or society, according to a "Perspective" article by faculty of Weill Cornell Medical College in the Jan. 6 New England Journal of Medicine.

7 Jan 2010

Study suggests pomegranates may prevent growth of breast cancer cells

US scientists have carried out a series of laboratory tests suggesting that natural compounds in pomegranates may prevent the growth of breast cancer cells.

7 Jan 2010

Balanced diet and exercise are the only reliable ways to lose weight

It's time to set the record straight. The only reliable way to lose weight is to eat less or exercise more. Preferably both.

7 Jan 2010

Study explains how H. pylori infection causes stomach cancer

Researchers report that Helicobacter pylori, the only bacterium known to survive in the harsh environment of the human stomach, directly activates an enzyme in host cells that has been associated with several types of cancer, including gastric cancer.

7 Jan 2010

Animal experiments show old antidepressant may reverse heart failure

A team of Johns Hopkins and other researchers have found in animal experiments that an antidepressant developed over 40 years ago can blunt and even reverse the muscle enlargement and weakened pumping function associated with heart failure.

6 Jan 2010

Annelie Wendeberg presents protocol for identification of environmental microbes

Metagenomics, the study of DNA isolated from samples of naturally occurring microbial populations, is rapidly growing. Improvements to cloning and sequencing techniques are allowing researchers to study microorganisms in environmental samples, and new knowledge of species interactions and community dynamics is emerging.

5 Jan 2010

Scientists determine how RNAi, a biological response to RNA, can regulate gene expression

A team of scientists at Cold Spring Harbor Laboratory (CSHL) has determined a hierarchical set of criteria that explain how the molecular precursors of gene-regulating small RNAs are sorted by the cellular machinery.

5 Jan 2010

Closer to the root cause of diabetes

A new research discovery published online in the FASEB Journal (http://www.fasebj.org) may change the perception and treatment of diabetes. That's because scientists have moved closer toward correcting the root cause of the disease rather than managing its symptoms. Specifically researchers identified a protein (G6PD protein) and its antioxidant product (NAPDH) that both prevent the death and promote the growth of cells which produce and release insulin in the pancreas (beta cells).

5 Jan 2010

Enzyme News and Research

Tocotrienol form of vitamin E prevents neural cell death and rescues the brain after stroke injury

Amicus Therapeutics presents corporate outlook for 2010 at Annual J.P. Morgan Healthcare Conference

New findings would allow doctors to tailor drug cocktails for particular viral strains

Cancer drug may provide an effective secondary treatment for gut tumor

New therapeutic treatment may provide a potential alternative to bone grafting operation

Researchers identify treatment to reduce health problems associated with enzyme defect

Research into "chemical chaperone" may lead to new treatments for heart attacks

Jiangsu Government grants $1.8M for research and development of hUC-MSC technologies

Researchers identify key epigenetic mechanism that helps explain cocaine's addictiveness

CSHL scientists explain how initiation of DNA replication is coordinated and controlled by kinase proteins

Phase 1 clinical trial of SIRT1 inhibitor for the treatment of Huntington’s Disease commenced

Researchers seek to defeat Alzheimer's disease by modifying mice's immune system

Authors explain why health care reform initiative should include CER

Study suggests pomegranates may prevent growth of breast cancer cells

Balanced diet and exercise are the only reliable ways to lose weight

Study explains how H. pylori infection causes stomach cancer

Animal experiments show old antidepressant may reverse heart failure

Annelie Wendeberg presents protocol for identification of environmental microbes

Scientists determine how RNAi, a biological response to RNA, can regulate gene expression

Closer to the root cause of diabetes

Biochemistry eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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