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Smoking may have a devastating effect on gastrointestinal health

Smoking may have a devastating effect on gastrointestinal health and increase a person's risk of developing pancreatic and liver cancer, according to new research presented today at Digestive Disease Week 2005 (DDW). Furthermore, data from the Nurses' Health Study shows that meat intake and smoking play a part in significantly increasing a woman's risk of colorectal cancer.

17 May 2005

New discovery sparks hope of safer dosage of Warfarin

The blood-thinning drug Warfarin tops the list of drug side-effects in Sweden. Patient sensitivity to Warfarin varies, which can lead to over-dosage and in certain cases to death.

17 May 2005

Drugs that block the enzyme Odc prevent the onset of cancers

The drug DFMO prevents cancer in laboratory models of lymphoma but fails to kill existing cancerous cells that have lost the ability to self-destruct, according to investigators at St. Jude Children's Research Hospital.

16 May 2005

Hormone Replacement Therapy (HRT) has a beneficial impact on cardiovascular health in hypertensive postmenopausal women

Oral Hormone Replacement Therapy (HRT) seems to have a beneficial impact on cardiovascular health in hypertensive postmenopausal women, researchers reported at the American Society of Hypertension Twentieth Annual Meeting held in San Francisco.

16 May 2005

Genetic biomarker that may improve quality of life during treatment for colorectal cancer

A Mayo Clinic-led study has revealed a genetic biomarker that can predict which patients are most likely to experience unwanted side effects from one of the most commonly used and highly effective chemotherapy regimens designed to treat colorectal cancer.

16 May 2005

Unsuspected protein CD147, regulates the production of plaque-forming peptides that are the defining feature of Alzheimer's

Researchers at the Department of Energy's Lawrence Berkeley National Laboratory have discovered an unsuspected subunit of the protein complex gamma-secretase, which plays a central role in Alzheimer's disease.

15 May 2005

Two-sided coating could breathe life into medical implants

By mimicking an adhesive protein secreted by mussels and a polymer that repels cells and proteins, researchers at Northwestern University have designed a versatile new two-sided coating that could breathe life into medical implants.

15 May 2005

Researchers identify mechanism which increases lung inflammation, making Chronic Obstructive Pulmonary Disorder (COPD) more severe

An international team of researchers has identified a mechanism which increases lung inflammation, making Chronic Obstructive Pulmonary Disorder (COPD) more severe, and potentially points towards new treatments.

11 May 2005

Healthy dose of fat is needed for a healthy metabolism

Just when we had all been convinced by information from just about every quarter, that fat was the bad guy of the diet kingdom, new research has found that a healthy dose of fat is needed for a healthy metabolism.

11 May 2005

Polypill improves survival rates for heart disease sufferers

A ‘polypill’ made up of a combination of drugs could extend the lives of thousands of patients with coronary heart disease, say researchers at The University of Nottingham.

10 May 2005

Cataract treatment in the blink of an eye

Researchers at the University of Canterbury, New Zealand are pioneering the development of an eye drop to halt the development of cataracts.

10 May 2005

Scientists inhibit tumor formation

By studying mice with skin cancer, researchers at the Huntsman Cancer Institute at the University of Utah discovered a way to inhibit a mutant gene found in up to 30 percent of human tumors.

9 May 2005

New fat is needed to clear old fat from the system

Where fat comes from determines whether the body can metabolize it effectively. Researchers at Washington University School of Medicine in St. Louis have found that the "old" fat stored in the body's peripheral tissues -- that is, around the belly, thighs or bottom -- can't be burned efficiently unless "new" fat is eaten in the diet or made in the liver.

9 May 2005

Simple and efficient method for creation of novel protein functions in an existing protein scaffold

By designing a molecular bridge, scientists at the University of Illinois at Urbana-Champaign have forged a successful pathway through a complex ocean of barriers: They've changed the function of a protein using a co-evolution approach.

8 May 2005

GM mice live longer and give hope for anti-aging treatments

U.S. scientists have produced genetically modified mice that live 20 per cent longer than normal and may have possibly discovered an approach to extending the human lifespan.

8 May 2005

Drug combinations improve survival for patients with heart disease

Patients with coronary heart disease who take a combination of three specific drugs have a better chance of survival than those taking single drugs, finds a study in this week's BMJ.

5 May 2005

Scientists take aim at virulent bacteria by decoding machinery of key control enzyme

By deciphering the ingenious mechanism used by a particular enzyme to modify bacterial chromosome chemistry, scientists have come a step closer to designing a new kind of drug that could stop virulent bacterial infections in their tracks. Their research will be published in the May 6 issue of the journal Cell.

5 May 2005

Mosaic Analysis with Double Markers (MADM) - A powerful new tool to study diseases and genetics

A powerful laboratory technique used by fruit fly geneticists for more than a decade is now available to scientists studying genes and diseases in mice.

5 May 2005

Scientists extend the lifespan of mice

Scientists at the University of Washington and their colleagues at other research centers have found a way to significantly extend the lifespan of mice while reducing the impact of the aging process. Their study, which will be published online by the journal Science on May 5, lends more credence to the free-radical theory of aging.

5 May 2005

Penn researchers demonstrate that a metabolic enzyme works through the tumor-suppressor protein p53 to control cellular replication

Researchers at the University of Pennsylvania School of Medicine have identified in normal cells that a common metabolic enzyme, which acts as a rheostat of cellular conditions, also controls cell replication.

4 May 2005

Enzyme News and Research

Smoking may have a devastating effect on gastrointestinal health

New discovery sparks hope of safer dosage of Warfarin

Drugs that block the enzyme Odc prevent the onset of cancers

Hormone Replacement Therapy (HRT) has a beneficial impact on cardiovascular health in hypertensive postmenopausal women

Genetic biomarker that may improve quality of life during treatment for colorectal cancer

Unsuspected protein CD147, regulates the production of plaque-forming peptides that are the defining feature of Alzheimer's

Two-sided coating could breathe life into medical implants

Researchers identify mechanism which increases lung inflammation, making Chronic Obstructive Pulmonary Disorder (COPD) more severe

Healthy dose of fat is needed for a healthy metabolism

Polypill improves survival rates for heart disease sufferers

Cataract treatment in the blink of an eye

Scientists inhibit tumor formation

New fat is needed to clear old fat from the system

Simple and efficient method for creation of novel protein functions in an existing protein scaffold

GM mice live longer and give hope for anti-aging treatments

Drug combinations improve survival for patients with heart disease

Scientists take aim at virulent bacteria by decoding machinery of key control enzyme

Mosaic Analysis with Double Markers (MADM) - A powerful new tool to study diseases and genetics

Scientists extend the lifespan of mice

Penn researchers demonstrate that a metabolic enzyme works through the tumor-suppressor protein p53 to control cellular replication

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