Erythromycin is a macrolide antibiotic that has an antimicrobial spectrum similar to or slightly wider than that of penicillin, and is often used for people who have an allergy to penicillins. For respiratory tract infections, it has better coverage of atypical organisms, including mycoplasma and Legionellosis. Erythromycin is an antibiotic produced from a strain of Streptomyces erythraeus.
Many top-selling drugs used to treat cancer and lower cholesterol are made from organic compounds called polyketides, which are found in nature but historically difficult for chemists to alter and reproduce in large quantities.
By guiding an enzyme down a new evolutionary pathway, a team of University of Wisconsin-Madison researchers has created a new form of an enzyme capable of producing a range of potential new therapeutic agents with anticancer and antibiotic properties.
Probiotics, the "good" bacteria in many dietary supplements, might counteract an unpleasant side effect for children on antibiotics, according to a new systematic review.
Investigators will begin offering Gleevec(R) (imatinib mesylate)* tablets to patients receiving placebo in a major North American clinical trial after an interim analysis showed participants with Kit-positive gastrointestinal stromal tumors treated with Gleevec following surgery were significantly less likely to experience a return of their cancer compared to those not taking this innovative therapy.
University of Minnesota and University of Michigan researchers have discovered a new method of developing antibiotics, an important step in fighting the growing number of drug-resistant infections.
Researchers in the U.S. say that methicillin-resistant Staphylococcus aureus or MRSA is the most common cause of skin and soft-tissue infections among patients presenting in emergency rooms across the country.
Escherichia coli is a commensal bacterium, which lives peacefully in our digestive tract. However, certain strains are pathogenic and are frequently incriminated in a broad spectrum of infections, affecting both farmed animals and humans (diarrhoea, urinary tract infections, food poisoning, septicaemia, neonatal meningitis, etc.).
Researchers have developed unique chemical dyes that have made it possible to see what the naked eye has never seen before: action potentials, or voltage changes, of cardiac cells - including those deep inside the heart, which trigger and determine the pace of heartbeats.
Physicians prescribe antibiotics for more than half of children with sore throat, exceeding the expected prevalence of strep throat, and used nonrecommended antibiotics for 27 percent of children who received an antibiotic prescription, according to a study in the November 9 issue of JAMA: The Journal of the American Medical Association.
As many as 15,000 sudden deaths each year in Europe and the U.S., may be caused by drugs commonly prescribed for psychiatric and gut disorders.
Non-cardiac drugs that interfere with the electrical activity controlling the heartbeat are associated with a three-fold risk of sudden cardiac death, according to Dutch research published (Wednesday 11 May) in Europe's leading cardiology journal, the European Heart Journal.
Using X-ray crystallography, researchers at Yale have "seen" the structural basis for antibiotic resistance to common pathogenic bacteria, facilitating design of a new class of antibiotic drugs, according to an article in Cell.
Howard Hughes Medical Institute researchers chiseling away at the problem of antibiotic resistance now have a detailed explanation of how the drugs' main cellular target in bacteria evolves to become resistant to some of these medications.
Two common antibiotics, Penicillin V and erythromycin, appear to have no benefit for most adults with acute laryngitis, says a research team led by Dr. Ludovic Reveiz of Bogota, Colombia.
Results of a UK study in this week’s issue of THE LANCET highlight how over the counter benzoyl peroxide (BEN-zoe-ill per-OX-ide) lotion is as good as prescription antibiotics for the treatment of mild to moderate facial acne.
People could be exposed to antibiotic-resistant bacteria from breathing the air from concentrated swine feeding facilities, according to researchers at the Johns Hopkins Bloomberg School of Public Health.
A Food and Drug Administration (FDA) analysis of three commonly prescribed drugs purchased from a Web site advertised as Canadian showed that so-called "Canadian Generics" bought from the Web site were fake, substandard and potentially dangerous.
The recommended maximum storage and transit temperatures for most medications is 25°C and are set by the pharmaceutical manufacturers.
Understanding the last step of protein synthesis – the basic process of translating DNA into its final protein product – just became more clear both literally and figuratively.
Results from an ongoing surveillance study, PROTEKT US (Prospective Resistant Organism Tracking and Epidemiology of the Ketolide Telithromycin – United States) Year 2 (2001-2002), suggest that KETEK® (telithromycin) is highly active in vitro against Streptococcus pneumoniae (S. pneumoniae) isolates, including those resistant to other antimicrobial agents.