Erythromycin is a macrolide antibiotic that has an antimicrobial spectrum similar to or slightly wider than that of penicillin, and is often used for people who have an allergy to penicillins. For respiratory tract infections, it has better coverage of atypical organisms, including mycoplasma and Legionellosis. Erythromycin is an antibiotic produced from a strain of Streptomyces erythraeus.
Researchers from North Carolina State University have found a way to fine-tune the molecular assembly line that creates antibiotics via engineered biosynthesis.
Diphtheria - a relatively easily-preventable infection - is evolving to become resistant to a number of classes of antibiotics and in future could lead to vaccine escape, warn an international team of researchers from the UK and India.
Biochar -- a charcoal-like substance made primarily from agricultural waste products -- holds promise for removing emerging contaminants such as pharmaceuticals from treated wastewater.
Research presented at ASM Microbe Online found that 43% of Staphylococcus bacteria found on exercise equipment in university gyms were ampicillin-resistant, with 73% of those isolates being resistant to multiple additional drugs.
Microorganisms that infect animals, such as dogs, have the potential to jump to humans and cause illness. Zoonosis is a disease that can spread from animals to humans. These diseases pose health risks, mainly that some types can become life-threatening. Now, a study warns that raw-type dog food contains high levels of multidrug-resistant bacteria, which has the potential of transmitting the bacteria between dogs and humans.
A new study published in the journal BMJ in February 2020 reports that macrolide or penicillin antibiotic consumption in pregnancy could be linked to several adverse health outcomes in children. These include major malformations, cerebral palsy, attention deficit hyperactivity disorder, and autism spectrum disorder.
Alarming results from a new study show that people in the United States buying fish antibiotics online and consuming them because they’re more affordable than to go visit a doctor. The study sheds light on the high costs of health care in the country and how citizens are struggling to afford basic services.
Antibiotic resistance in bottlenose dolphins shows that up to 88% of pathogenic organisms in this species is resistant to one or more antibiotics. This finding offers very useful insights into the identical phenomenon in humans. This species is termed a sentinel species, which means it reflects environmental risks to humans in advance of their occurrence in humans.
The River Thames is rapidly becoming a breeding pool for antibiotic-resistant bacteria, according to a new study, which underlines the urgent need to cut down the amount of antibiotics currently being discharge into the river by at least 80% to arrest this trend.
A new study led by researchers at Indiana University has found that women and older adults who use multiple prescription drugs are significantly more likely to be prescribed pills whose combination produces dangerous side effects.
Central London's freshwater sources contain high levels of antibiotic resistant genes, with the River Thames having the highest amount, according to research by UCL.
A JRC report brings together data on antibiotic levels in water, showing that small concentrations have found their way into a range of Europe's waterbodies.
A scientific team from Case Western Reserve University School of Medicine and Cleveland Clinic has developed a new way to identify second-line antibiotics that may be effective in killing germs already resistant to a first-line antibiotic - potentially helping overcome antibiotic resistance.
A University of Illinois team of researchers led by chemistry professor M. Christina White has developed a new manganese-based catalyst that can change the structure of druglike molecules to make new drugs, advancing the pace and efficiency of drug development.
Vertex Pharmaceuticals Incorporated today announced the U.S. Food and Drug Administration approved KALYDECO® (ivacaftor) to include use in children with cystic fibrosis ages 12 to <24 months who have at least one mutation in their cystic fibrosis transmembrane conductance regulator gene that is responsive to KALYDECO based on clinical and/or in vitro assay data.
A recent study has found that changes in microbial communities within the reproductive tract of pregnant women were strongly linked to premature birth.
Changes to the communities of microbes living in the reproductive tract of pregnant women could help to spot those at risk of giving birth prematurely.
Findings from a study that looked at susceptibility trends of Staphylococcus aureus in U.S. hospital patients showed that key antibiotics used to treat the bacteria became more active over the course of the study, a rare occurrence.
Two Swiss research teams from the University of Bern and the ETH Zurich have developed a new method to shed light onto a mostly unknown process of bacterial protein production. Their results could be used for the design of new antibiotics.
The discovery of a chemical compound that halts the production of a small set of proteins while leaving general protein production untouched suggests a new drug search strategy: Find compounds that target undesired proteins before they are even made.