Erythromycin is a macrolide antibiotic that has an antimicrobial spectrum similar to or slightly wider than that of penicillin, and is often used for people who have an allergy to penicillins. For respiratory tract infections, it has better coverage of atypical organisms, including mycoplasma and Legionellosis. Erythromycin is an antibiotic produced from a strain of Streptomyces erythraeus.
The use of the element fluorine to modify active substances is an important tool in modern drug development.
An international team of researchers has developed a method for altering one class of antibiotics, using microscopic organisms that produce these compounds naturally.
Years of toil in the laboratory have revealed how a marine bacterium makes a potent anti-cancer molecule.
A research team at the Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute in Jena, Germany has developed a new method to produce complex natural products in amoebae.
Scientists may have made a giant leap in fighting the biggest threat to human health by using supercomputing to keep pace with the impressive ability of diseases to evolve.
Antibiotics help us to treat bacterial infections and save millions of lives each year. But they can also harm the helpful microbes residing in our gut, weakening one of our body's first lines of defense against pathogens and compromising the multiple beneficial effects our microbiota has for our health.
Most medications being tested today in clinical trials for the treatment of coronavirus disease 2019 (COVID-19) have been repurposed from other indications. These are typically not tested in pregnant women. A new study, published in the journal PLOS ONE, summarizes what is known about the safety of these drugs in this group.
Researchers from North Carolina State University have found a way to fine-tune the molecular assembly line that creates antibiotics via engineered biosynthesis.
Diphtheria - a relatively easily-preventable infection - is evolving to become resistant to a number of classes of antibiotics and in future could lead to vaccine escape, warn an international team of researchers from the UK and India.
Biochar -- a charcoal-like substance made primarily from agricultural waste products -- holds promise for removing emerging contaminants such as pharmaceuticals from treated wastewater.
Research presented at ASM Microbe Online found that 43% of Staphylococcus bacteria found on exercise equipment in university gyms were ampicillin-resistant, with 73% of those isolates being resistant to multiple additional drugs.
Microorganisms that infect animals, such as dogs, have the potential to jump to humans and cause illness. Zoonosis is a disease that can spread from animals to humans. These diseases pose health risks, mainly that some types can become life-threatening. Now, a study warns that raw-type dog food contains high levels of multidrug-resistant bacteria, which has the potential of transmitting the bacteria between dogs and humans.
A new study published in the journal BMJ in February 2020 reports that macrolide or penicillin antibiotic consumption in pregnancy could be linked to several adverse health outcomes in children. These include major malformations, cerebral palsy, attention deficit hyperactivity disorder, and autism spectrum disorder.
Alarming results from a new study show that people in the United States buying fish antibiotics online and consuming them because they’re more affordable than to go visit a doctor. The study sheds light on the high costs of health care in the country and how citizens are struggling to afford basic services.
Antibiotic resistance in bottlenose dolphins shows that up to 88% of pathogenic organisms in this species is resistant to one or more antibiotics. This finding offers very useful insights into the identical phenomenon in humans. This species is termed a sentinel species, which means it reflects environmental risks to humans in advance of their occurrence in humans.
The River Thames is rapidly becoming a breeding pool for antibiotic-resistant bacteria, according to a new study, which underlines the urgent need to cut down the amount of antibiotics currently being discharge into the river by at least 80% to arrest this trend.
A new study led by researchers at Indiana University has found that women and older adults who use multiple prescription drugs are significantly more likely to be prescribed pills whose combination produces dangerous side effects.
Central London's freshwater sources contain high levels of antibiotic resistant genes, with the River Thames having the highest amount, according to research by UCL.
A JRC report brings together data on antibiotic levels in water, showing that small concentrations have found their way into a range of Europe's waterbodies.
A scientific team from Case Western Reserve University School of Medicine and Cleveland Clinic has developed a new way to identify second-line antibiotics that may be effective in killing germs already resistant to a first-line antibiotic - potentially helping overcome antibiotic resistance.