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Prime editing takes gene therapy to the next level

This study is led by Prof. Xianqun Fan (Department of Ophthalmology, Shanghai Jiao Tong University School of Medicine Affiliated Ninth People's Hospital).

27 Jan 2024

Study offers insights into who's at risk for long COVID among immunocompromised patients

Early in the pandemic, clinicians noticed that certain immunocompromised patients were experiencing persistent SARS-CoV-2 infections, some lasting weeks to months at a time.

26 Jan 2024

Ancient Brazilian genomes may hold the secrets of treponemal evolutionary history

Study reconstructs four ancient treponeme genomes from 2,000-year-old Brazilian remains, revealing their close relation to the bejel-causing Treponema pallidum endemicum and challenging previous hypotheses about treponeme subspecies adaptability.

25 Jan 2024

Study links European West Nile outbreaks to agriculture, urbanization, and bird migration

The spread of West Nile virus in Europe is strongly linked to agricultural activities, urbanization, and bird migration, according to a modelling study published January 25, 2024 in the open-access journal PLOS Pathogens by Lu Lu from the University of Edinburgh, UK, and collaborators belonging to a large European collaborative consortium under the VEO (Versatile Emerging infectious disease Observatory) project.

25 Jan 2024

Unlocking how animals control gut bacteria could aid human health

Thousands of types of bacteria live in the human gut. They help digest the food we eat and absorb nutrients, but these bacteria don't just do this to be kind to humans, there is a benefit for them too.

24 Jan 2024

Study provides valuable insights into the evolutionary dynamics of hepatitis E virus

A combination therapy with multiple drugs is more effective than just one active compound. To begin with, at least.

23 Jan 2024

Unraveling the logic of genes with Boolean network models

Over the last 20 years, researchers in biology and medicine have created Boolean network models to simulate complex systems and find solutions, including new treatments for colorectal cancer.

23 Jan 2024

Study highlights the complex genetic landscape that drives modern tardigrade ecology

Tardigrades may be nature's ultimate survivors. While these tiny, nearly translucent animals are easily overlooked, they represent a diverse group that has successfully colonized freshwater, marine, and terrestrial environments on every continent, including Antarctica.

22 Jan 2024

Biodesign needs open-ended systems for future innovation

Scientists working on biological design should focus on the idiosyncrasies of biological systems over optimization, according to new research.

19 Jan 2024

Study shows Omicron variants evade immune system like predecessors, suggesting key evolutionary trait in SARS-CoV-2

Researchers compared SARS-CoV-2 Omicron variant of concern replication in human cell lines and primary airway cultures and measured host responses to infection.

19 Jan 2024

Global mortality trends reveal convergence clubs and diverging patterns

Study analyzes global mortality trends from 1990 to 2030, identifying five convergence clubs of countries with similar mortality characteristics, revealing patterns of convergence and divergence in mortality and longevity.

18 Jan 2024

Statistical innovation sheds light on global progress in living longer

When it comes to trends in mortality over the last thirty years, countries around the world can be grouped into five clusters, roughly representing the five continents, according to a new study published January 17, 2024, in the open-access journal PLOS ONE by David Atance of Universidad de Alcalá, Spain, and colleagues.

17 Jan 2024

Researchers uncover the role of inherited genetic variants in rare type of blood cancer

Large-scale genetic analysis has helped researchers uncover the interplay between cancer-driving genetic mutations and inherited genetic variants in a rare type of blood cancer.

17 Jan 2024

New Omicron variants relearn immunity dodging tricks

Recent SARS-CoV-2 variants such as BA.4 and BA.5 developed abilities missing from the first Omicron variants that allowed them to overcome humans' innate immunity, according to research from UCL.

16 Jan 2024

Study finds that HIV populations in people with higher viral loads also have higher rates of viral recombination

Researchers investigated whether denser intrahost HIV populations had a higher incidence of coinfection and recombination.

15 Jan 2024

Ancient genomes reveal origins of multiple sclerosis risk in Europe

Researchers investigated the variables contributing to geographical heterogeneity in multiple sclerosis prevalence and the impact of genetic and environmental factors on the disease's development.

15 Jan 2024

Ancient DNA traces multiple sclerosis origins to 5,000-year-old migrations

Researchers create the world's largest ancient human gene bank, linking genes to multiple sclerosis risk and tracing its origins to migrations 5,000 years ago.

13 Jan 2024

Ancient DNA reveals first prehistoric cases of Turner and Jacob's syndromes

Ancient DNA reveals first prehistoric cases of Turner and Jacob's syndromes, with new technique enhancing chromosome analysis

13 Jan 2024

Planning prompts show promise in improving prescribing safety

Physicians who are notified that a patient has died of a drug overdose are more judicious in issuing controlled substances if the notification includes a plan for what to do during subsequent patient visits, according to a study published today in Nature Communications.

13 Jan 2024

Study explains why "being in love" makes us tunnel visioned

Love is blind, the saying goes, and thanks to a world-first Australian study, we are now a step closer to understanding why.

13 Jan 2024

Evolution News and Research

Prime editing takes gene therapy to the next level

Study offers insights into who's at risk for long COVID among immunocompromised patients

Ancient Brazilian genomes may hold the secrets of treponemal evolutionary history

Study links European West Nile outbreaks to agriculture, urbanization, and bird migration

Unlocking how animals control gut bacteria could aid human health

Study provides valuable insights into the evolutionary dynamics of hepatitis E virus

Unraveling the logic of genes with Boolean network models

Study highlights the complex genetic landscape that drives modern tardigrade ecology

Biodesign needs open-ended systems for future innovation

Study shows Omicron variants evade immune system like predecessors, suggesting key evolutionary trait in SARS-CoV-2

Global mortality trends reveal convergence clubs and diverging patterns

Statistical innovation sheds light on global progress in living longer

Researchers uncover the role of inherited genetic variants in rare type of blood cancer

New Omicron variants relearn immunity dodging tricks

Study finds that HIV populations in people with higher viral loads also have higher rates of viral recombination

Ancient genomes reveal origins of multiple sclerosis risk in Europe

Ancient DNA traces multiple sclerosis origins to 5,000-year-old migrations

Ancient DNA reveals first prehistoric cases of Turner and Jacob's syndromes

Planning prompts show promise in improving prescribing safety

Study explains why "being in love" makes us tunnel visioned

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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