Ex Vivo News and Research

RSS

Marijuana and e-cigarettes both increase risks of cardiac arrhythmias

In a recent study published in the Heart Rhythm journal, researchers at the University of California, San Francisco, assessed the relationship between different types of inhaled marijuana or tobacco product usage with ventricular and atrial arrhythmias.

17 Nov 2022

Mechanically active adhesive prevents and supports the recovery from muscle atrophy

Muscles waste as a result of not being exercised enough, as happens quickly with a broken limb that has been immobilized in a cast, and more slowly in people reaching an advanced age.

14 Nov 2022

First preclinical model to study the pathobiology of appendiceal cancer

Appendiceal cancer (malignancies of the appendix, a small tissue pouch that is part of the gastrointestinal tract) is very rare, occurring in perhaps one or two people per 1 million per year.

1 Nov 2022

Overview of the roles of neutrophils in systemic autoimmune and autoinflammatory diseases

Researchers assess the role of neutrophil extracellular traps (NETs) in systemic autoimmune and autoinflammatory disorders.

23 Oct 2022

Study determines how fibroblasts play a role in tumor's ability to generate anti-HER2 therapy resistance

A study led by researchers at the Hospital del Mar Medical Research Institute (IMIM-Hospital del Mar) has determined the role that fibroblasts, the cells that contribute to tissue formation, play in a tumor's ability to generate resistance to the most common biological treatment for HER2.

14 Oct 2022

Study using human and animal-derived cell lines suggests human origin of SARS-CoV-2 Omicron variant

Researchers examined the replicative capacity of seven SARS-CoV-2 isolates in 17 cell lines to understand their phenotypic variations and host range.

7 Oct 2022

How COVID-19 affects the female reproductive system

A new review in the Biology of Reproduction journal analyzed the relationship between the immune system and the female reproductive system while focusing on the effects of COVID-19-associated immune responses on the reproductive system. The study searched PubMed to identify peer-reviewed literature in English up to May 2022 and finally included 83 studies.

3 Oct 2022

Mount Sinai study suggests significant role of reactive oxygen species in maintaining healthy intestines

Mount Sinai researchers have published one of the first studies to demonstrate the importance of reactive oxygen species in maintaining stem cell function and preventing inflammation during wound repair, which could provide greater insights into the prevention and treatment of inflammatory bowel diseases (IBD), according to findings published in the journal Gut on October 3.

3 Oct 2022

Can the gut be an alternative route for SARS-CoV-2 entry?

Researchers reviewed the gut pathophysiology of SARS-CoV-2 infection.

28 Sep 2022

SARS-CoV-2 generates amyloid in cerebral spinal fluid

In a recent study posted to the bioRxiv* preprint server, an international team of researchers demonstrated amyloid aggregation due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in human cerebrospinal fluid (CSF).

20 Sep 2022

Research reveals the role of microglia-neuron connections during brain development

The Laboratory of Neuroimmunology of the Institute of Experimental Medicine, Budapest, Hungary, led by Ádám Dénes, describes the presence of a direct interaction site between microglial cells and the cell body of developing neurons, and reveals its role during brain development.

20 Sep 2022

New mechanistic insights on the origin of SARS-CoV-2-induced neurological disorders

Researchers explored the effect of SARS-CoV-2 exposure on the brain.

20 Sep 2022

Parenteral-prime mucosal boost an effective strategy to protect against SARS-CoV-2

In a recent study published in the journal eBioMedicine, researchers in Denmark and Sweden administered a cationic liposome-adjuvanted severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein subunit vaccine as a subcutaneous (s.c.) prime-intranasal (i.n.) boost strategy to elicit mucosal immune responses among SARS-CoV-2-infected Syrian hamsters.

14 Sep 2022

Mucosal vaccination triggers superior T cell response against SARS-CoV-2 variants

In a recent study posted to the bioRxiv* server, researchers in Singapore and the United States demonstrated that intranasal (I.N.) delivery of a mucosal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination triggered a superior T cell response compared to an equivalent dose of antigen delivered by the subcutaneous (S.C.) route.

12 Sep 2022

Tumor-infiltrating lymphocytes therapy treats cancers at a large scale

A novel treatment strategy with personalized cell therapy significantly improves progression-free survival compared to standard immunotherapy in patients with advanced melanoma, according to ground-breaking results reported at the ESMO Congress 2022 from the phase 3 M14TIL trial.

12 Sep 2022

Ex Vivo News and Research

Marijuana and e-cigarettes both increase risks of cardiac arrhythmias

Mechanically active adhesive prevents and supports the recovery from muscle atrophy

First preclinical model to study the pathobiology of appendiceal cancer

Overview of the roles of neutrophils in systemic autoimmune and autoinflammatory diseases

Study determines how fibroblasts play a role in tumor's ability to generate anti-HER2 therapy resistance

Study using human and animal-derived cell lines suggests human origin of SARS-CoV-2 Omicron variant

How COVID-19 affects the female reproductive system

Mount Sinai study suggests significant role of reactive oxygen species in maintaining healthy intestines

Can the gut be an alternative route for SARS-CoV-2 entry?

SARS-CoV-2 generates amyloid in cerebral spinal fluid

Research reveals the role of microglia-neuron connections during brain development

New mechanistic insights on the origin of SARS-CoV-2-induced neurological disorders

Parenteral-prime mucosal boost an effective strategy to protect against SARS-CoV-2

Mucosal vaccination triggers superior T cell response against SARS-CoV-2 variants

Tumor-infiltrating lymphocytes therapy treats cancers at a large scale

Ultrasound color Doppler twinkling may aid the detection of breast biopsy markers

The role of some important antioxidants in major clinical outcomes of subjects with COVID-19

A rapid and efficient method of identifying neutralizing nanobodies directed against SARS-CoV-2

CD98 identified as a key mediator of pro-fibrotic and acute inflammatory responses in the lung

Study contributes to better understanding of the changes in kinase activity in renal cell carcinoma

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

Latest News