Exhaustion News and Research

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Study shows role of exhausted regulatory T cells in allergic reactions

Researchers have evidence that the specialized T cells responsible for maintaining a balanced immune response are vulnerable to exhaustion that disrupts normal functioning and may even contribute to allergic reactions.

23 Aug 2017

Smoking increases risk of developing frailty in older adults

A recent paper published in Age & Ageing, the scientific journal of the British Geriatrics Society, finds that current smoking in older people increases the risk of developing frailty, though former smokers did not appear to be at higher risk.

17 Aug 2017

Drowning can occur even while on dry land

Drowning is one of the biggest problems in the United States, and considering the number of people who will head to bodies of water to cool off this summer, we are entering the riskiest months.

21 Jul 2017

Depression causes alterations in the brain's structure, study finds

Changes in the brain's structure that could be the result of depression have been identified in a major scanning study.

21 Jul 2017

Lunatic fringe gene plays role in regulating fate of neural stem cells

The discovery that the brain can generate new cells - about 700 new neurons each day - has triggered investigations to uncover how this process is regulated.

19 Jul 2017

EPO blood doping has little effect on amateur cyclists’ road race performance

According to a new study published in The Lancet Haematology, recombinant human erythropoietin (rHuEPO), a performance augmenting drug has little effects on high-intensity laboratory cycling test among well-trained amateur cyclists; yet in the laboratory time trial test and endurance road-race up Mont Ventoux (France), the augmenting effects were typically undetectable.

30 Jun 2017

Discovery of T cell exhaustion offers new pathway to more powerful immunotherapies

St. Jude Children's Research Hospital immunologists have discovered how immune cells called T cells become "exhausted" -- unable to do their jobs of attacking invaders such as cancer cells or viruses.

28 Jun 2017

Researchers discover same kind of T-cell exhaustion in IBS-D patients

Australian researchers have for the first time discovered that a specific type of irritable bowel syndrome is associated with exhaustion of the immune system in patients.

21 Jun 2017

Researchers explore link between psychological symptoms and length of sick leave

The duration of a person's unfitness for work is determined by more than his/her primary diagnosis. Patients often report psychological problems and a feeling of being burnt out.

30 May 2017

Summer perils and ways to avoid, treat them

Summer can bite. It can burn or itch. It can make you extremely sick…or worse.

27 May 2017

Fennel effective in management of postmenopause symptoms, study shows

Fennel, an anise-flavored herb used for cooking, has long been known for its health benefits for a variety of issues, including digestion and premenstrual symptoms.

17 May 2017

New drug mimics health effects of exercise, say researchers

Scientists have managed to mimic the health effects of exercise in mice, simply by using a pill, according to a study published in Cell Metabolism. The drug activated a genetic pathway that is triggered by running, which led mice to burn off more fat and increase their stamina levels, despite them being sedentary.

4 May 2017

People with burnout symptoms react faster to negative sounds of voice, study reveals

Approximately every fourth working aged Finn experiences symptoms of burnout that include exhaustion, cynicism and reduced professional efficacy and often also difficulties in concentration and memory.

10 Apr 2017

Men with high levels of anabolic hormones less likely to develop worsening frailty, study suggests

A new study suggests that middle-age and elderly men are less likely to develop worsening frailty if they have high levels of certain anabolic hormones, which are muscle- and bone-building hormones.

3 Apr 2017

City of Hope researchers to highlight basic cancer research and population studies at AACR meeting

City of Hope, a world-renowned independent research and cancer and diabetes treatment center, will highlight a variety of basic research and population studies at the annual meeting of the American Association for Cancer Research at the Walter E. Washington Convention Center in Washington, D.C., April 1 to 5.

28 Mar 2017

Early treatment with stem cells can safely help recovery in stroke patients, study shows

A multicenter trial looking at whether a single dose of millions of adult, bone-marrow-derived stem cells can aid stroke recovery indicates it's safe and well-tolerated by patients but may not significantly improve their recovery within the first three months, researchers report.

20 Mar 2017

LJI researchers unravel molecular underpinnings of exhausted T cells

One reason we survive into adulthood is that cell-killing T cells usually recognize and eliminate cancerous or pathogen-infected cells.

15 Mar 2017

Exercise helps gastrointestinal cancer patients cope better with side effects of chemotherapy

Walking or jogging helps patients with advanced gastrointestinal cancer to cope better with the side effects of chemotherapy.

10 Mar 2017

Researchers reveal how overloading of protein transport mechanisms triggers cellular defects

Researchers at Okayama University report in Scientific Reports how the overloading of protein transport mechanisms affects cell functioning. Over-expression of different types of target proteins leads to cellular growth defects, and the mechanism for transporting proteins out of a cell nucleus has the lowest over-expression tolerance.

7 Mar 2017

Parental Box aims to save families with children from exhaustion

Parental Box, a semifinalist team in the Helsinki Challenge science-based competition, wants to save families with children from exhaustion and help parents keep the spark alive with its "mental maternity box".

22 Feb 2017