Exhaustion News and Research

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Women and minorities bear the brunt of medical misdiagnosis

Charity Watkins sensed something was deeply wrong when she experienced exhaustion after her daughter was born.

18 Jan 2024

Are vacation days taken and working while on vacation associated with physician burnout?

Associations between the vacation days taken by physicians per year.

17 Jan 2024

Study links early screen time to atypical sensory processing in toddlers

Babies and toddlers exposed to television or video viewing may be more likely to exhibit atypical sensory behaviors, such as being disengaged and disinterested in activities, seeking more intense stimulation in an environment, or being overwhelmed by sensations like loud sounds or bright lights, according to data from researchers at Drexel's College of Medicine published today in the journal JAMA Pediatrics.

9 Jan 2024

California is poised to protect workers from extreme heat — indoors

The stifling heat inside some warehouses where workers might spend 10-hour days isn't just a summer problem. In Southern California, it can feel like summer all year.

3 Jan 2024

Transcendental Meditation significantly reduces PTSD, anxiety, and burnout in nurses during COVID-19

Frontline nurses who learned the Transcendental Meditation technique during the COVID-19 pandemic showed rapid and significant improvements in flourishing, PTSD, anxiety, and burnout over 3 months compared to controls, according to a study published today in the Journal of Nursing Administration.

11 Dec 2023

Phase I clinical trial of new CAR T cell therapy AT101 shows promising early responses

Early results from a Phase I clinical trial of AT101, a new CAR T cell therapy that uses a distinct binding mechanism to target CD19, show a 100 percent complete response (CR) rate at the higher dose levels studied in the trial, according to researchers from the University of Pennsylvania Perelman School of Medicine and Penn Medicine's Abramson Cancer Center.

11 Dec 2023

Exercise may become part of standard treatment for metastatic breast cancer, study suggests

Among patients with metastatic breast cancer, those who took part in a nine-month structured exercise program reported less fatigue and an improved quality of life compared to those who did not undergo the exercise program, according to results from the PREFERABLE-EFFECT trial presented at the San Antonio Breast Cancer Symposium, held December 5-9, 2023.

7 Dec 2023

Study reveals underestimated heat risks in climate change, highlighting challenges for aging population

Study in 'Nature Communications' presents a new model integrating physiological factors to more accurately predict human survivability and livability under heat stress due to climate change.

30 Nov 2023

Study finds diet-derived trans-vaccenic acid boosts anti-tumor immunity

Dietary components that impact anti-tumor immunity.

28 Nov 2023

Scientists uncover key to enhancing cancer-killing T cells

T cells are the key immune system component involved in killing cancer. Tumors produce signals that turn off these T cells, partially by forcing them to progressively differentiate (mature) into a hypofunctional state known as exhaustion.

21 Nov 2023

New lipidic peptide IK14004 shows promise in treating cancer and reducing autoimmune complications

A lipidic peptide, named IK14004.

15 Nov 2023

New approach to CAR T cell therapy may extend treatment effectiveness

CAR T cell therapy, a powerful type of immunotherapy, has begun to revolutionize cancer treatment. Pioneered at Memorial Sloan Kettering Cancer Center (MSK), the therapy involves engineering a patient's T cells so they recognize and attack cancer cells.

14 Nov 2023

Overcoming T-cell exhaustion: A new hope for CAR-T cell therapy

CAR-T cell therapy is a last hope for many patients with blood, bone marrow or lymph gland cancer when other treatments such as chemotherapy are unsuccessful.

6 Nov 2023

Decoding long COVID, pathophysiology, epidemiology, diagnosis, and management

Comprehensive review unravels the complexities of long COVID, spanning pathophysiology to management strategies, and underscores the need for targeted therapies and early diagnosis.

5 Nov 2023

Influence of employment during COVID-19 on cognitive and motor functions among elders

The effects of employment on geriatric health during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak.

1 Nov 2023

Using synthetic biology to develop smarter cell therapies for cancer patients

We are embarking on an unprecedented era of therapeutic development enabled by live cell engineering.

31 Oct 2023

Stroke experts map out path for better patient outcomes

Scientists from The Florey are among the world's leading stroke experts who have mapped out how researchers and clinicians can improve outcomes for people who have survived a stroke.

12 Oct 2023

What is the burnout rate among US physicians over the past 5 years?

Physician burnout is a major issue affecting the quality and availability of healthcare in the US. The rising rate of this problem spurred a recent study aimed at identifying its roots.

6 Oct 2023

Unlocking the future of cancer care: Overcoming challenges in personalized neoantigen vaccine development

Challenges associated with the development and design of neoantigen cancer vaccines.

5 Oct 2023

Could a Poria cocos extract be the key to conquering insomnia?

The study reveals that Poria cocos extract significantly improves sleep quality in insomniacs, increasing total sleep time and enhancing REM sleep duration. While promising, further investigations are needed to validate these findings and explore the effects of other active compounds within P. cocos.

3 Oct 2023