Exosomes News and Research

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Detection of mouth, throat cancer through saliva testing could become reality

Cancer of the throat and mouth (oropharyngeal cancers, OPC) are common, and are increasing in incidence especially among younger people. However, these are difficult to diagnose as they are not seen either by the patient or during routine medical examinations.

15 Dec 2019

New technique may lead to earlier and easier detection of mouth and throat cancer

Unfortunately, cancers that occur in the back of the mouth and upper throat are often not diagnosed until they become advanced, partly because their location makes them difficult to see during routine clinical exams.

13 Dec 2019

Research could pave way for regenerative TBI-IV therapy

A team of researchers from the University of Georgia's Regenerative Bioscience Center has found that neural exosomes- "cargo" molecules within the nervous system that carry messages to the brain- can minimize or even avert progression of traumatic brain injury when used as part of a new cell-to-cell messaging technology.

12 Dec 2019

Research shows how cilia and exocyst contribute to extracellular vesicle production

Although the cilium has been known to scientists for more than 100 years, it is only recently that it has been acknowledged to play important roles in physiology.

25 Nov 2019

Using 'Trojan horses' to kill tumor cells from within

Using "Trojan horses" to combat cancer from within the tumor cells themselves without damaging healthy tissues is the aim of this new tool created by researchers from the University of Granada, the Institute of Nanoscience of Aragon, the University of Zaragoza, and the Cancer Research UK Edinburgh Centre at the University of Edinburgh.

19 Nov 2019

Scientists find driver for more deadly prostate cancer

A transcription factor that aids neuron function also appears to enable a cell conversion in the prostate gland that can make an already recurrent cancer even more deadly, scientists say.

13 Nov 2019

Study: Spherical exosomes could help in treating acute kidney injury

Like a swarm of construction workers in the aftermath of a destructive storm, cargo-filled, nanometer-sized spheres arrive on the scene following an acute kidney injury.

5 Nov 2019

Protein may help predict, prevent and treat brain metastases

A protein that breast, lung and other cancers use to promote their spread--or metastasis--to the brain, has been identified by a team led by Weill Cornell Medicine and New York-Presbyterian investigators. The protein, CEMIP, will now be a focus of efforts to predict, prevent and treat brain metastases, which are a frequent cause of cancer deaths.

4 Nov 2019

Serum flotillin level can serve as blood marker for early diagnosis of Alzheimer's disease

Currently, best-characterized indicators for Alzheimer's disease diagnosis are the decreased levels of amyloid β-protein 42 and increased levels of phosphorylated tau in cerebrospinal fluid.

4 Nov 2019

BIA Separations launches CORNERSTONE Exosome Process Development Solution

BIA Separations, a leading bio-chromatography development and manufacturing company, today announced the introduction of its CORNERSTONE Exosome Process Development Solution, designed to help drug-developers overcome critical development bottlenecks in the preparation of exosomes for clinical use.

10 Oct 2019

New needle-free 'exosome' treatment to reduce wrinkles in UV-exposed mice

In the quest for a more youthful appearance, many people slather ointments on their skin or undergo injections of dermal fillers. But topical treatments often aren't very effective because they don't penetrate deep within the skin, whereas the results from injections typically last for only a few months and can be painful.

25 Sep 2019

Researchers develop new anti-cancer nanomedicine for targeted chemotherapy

Researchers at the University of Helsinki in collaboration with researchers from Åbo Akademi University, Finland and Huazhong University of Science and Technology, China have developed a new anti-cancer nanomedicine for targeted cancer chemotherapy.

17 Sep 2019

Study reveals how breast cancer uses exosomes to metastasize to the brain

Metastasizing breast cancers typically seek out the bones, lung, and brain. Brain metastases are especially dangerous; many women survive for less than a year after diagnosis. How is the cancer able to get past the blood brain barrier? And can it be blocked?

13 Sep 2019

BIA Separations launches Cornerstone AAV Process Development Service to improve gene therapy production

BIA Separations, a leading bio-chromatography development and manufacturing company, today announced the introduction of CORNERSTONE AAV Process Development Service, a program of integrated process development services and novel technology designed to improve the robustness and yield of AAV-based gene therapy production, while improving the safety of therapeutic products.

12 Sep 2019

New method maps surface protein complements on large numbers of individual exosomes

There is a growing demand for diagnostic markers for early disease detection and prognosis. Exosomes are potential biomarkers for cancer progression and neurodegenerative disease but it can be difficult to identify what tissue a specific exosome comes from.

27 Aug 2019