External beam radiotherapy otherwise known as teletherapy, is the most frequently used form of radiotherapy. The patient sits or lies on a couch and an external source of radiation is pointed at a particular part of the body. Kilovoltage (also known as, superficial) x-rays are used for treating skin cancer and superficial structures. Megavoltage (or deep) X-rays are used to treat deep-seated tumours (eg bladder, bowel, prostate, lung, brain).
Researchers involved in the phase II NRG Oncology RTOG 0526 trial studying low dose rate (LDR) prostate brachytherapy (BT) following local recurrence (LR) after external beam radiotherapy (EBRT) for patients with low-to-intermediate risk prostate cancer reported late Grade 3 gastrointestinal and genitourinary adverse events (AEs) occurring in 14% of trial participants.
Newly diagnosed prostate cancer patients have multiple standard-of-care treatment options available, but many are not fully informed of their choices.
A Phase III, NRG Oncology clinical trial that compared radiosurgery or stereotactic body radiotherapy to the conventional radiotherapy for patients with spinal metastases indicated that there was no statistically significant difference between the treatments for pain response, adverse events, FACT-G, BPI, and EQ-5D scores.
A new way of concentrating radiotherapy dose in tumours, while minimising damage to healthy cells, has been proposed in research led by scientists at the University of Strathclyde.
UK doctors and surgeons have formulated what is probably the world's first clinical guidance on anal sex before, during, and after diagnosis and treatment for prostate cancer.
Women with early, low risk, hormone-driven breast cancer are less likely to have a recurrence of their disease if they have radiotherapy after surgery, as well as anti-hormone treatment, according to results from a trial that has followed 869 women for ten years.
Interstitial brachytherapy uses slightly radioactive particles implanted into the prostate to deliver radiation directly to the tumour (low-dose-rate, LDR).
A subset of patients with low-risk breast cancer is highly unlikely to see cancer return following breast conservation surgery but can lower that risk even further with radiation therapy, finds a new long-term clinical trial report.
A coveted British Medical Journal award was recently bestowed on the Papillon Contact X-ray Brachytherapy team at the Clatterbridge Cancer Centre. The Cancer Care Team of the year category was won by the entry—Papillon for Rectal Cancer.
NICE (National Institute for Health and Care Excellence) has announced a new Medtech Innovation Briefing (MIB) stating that NHS doctors and commissioners may consider Single Dose Intraoperative Radiotherapy (SD-IORT) using the Xoft Axxent electronic brachytherapy system with ORL managed service as a treatment option for early stage breast cancer patients.
The American Society for Radiation Oncology recently issued a new clinical practice statement, "Appropriate Customization of Radiation Therapy for Stage II and III Rectal Cancer: An ASTRO Clinical Practice Statement Using the RAND/UCLA Appropriateness Method."
In the South East of England, a patient experience study of 18 early stage breast cancer patients who opted for single dose intraoperative radiotherapy, found positive patient reported outcomes for this alternative to standard daily external beam radiotherapy.
Hitachi, Ltd. has announced it has received FDA 510(k) clearance for commercial supply of the new PROBEAT-V system, which it designed and developed for Mayo Clinic in Rochester, MN. Treatments began in late June and the first patient treatment was completed in August 2015.
The University of the West of England (UWE Bristol) is the first Higher Education Institution (HEI) in the UK to sign up for the very latest version of a powerful simulated Radiotherapy Treatment Planning System (RTPS), which has been futureproofed.
Results from a randomised controlled trial to compare the use of permanent radioactive implants (brachytherapy) with dose-escalated external beam radiotherapy in patients with prostate cancer show that the men who received brachytherapy were twice as likely to be cancer-free five years later.
Agenus Inc., announced final results from a single-arm, multi-institutional, open-label, Phase 2 study showing that patients with newly diagnosed glioblastoma multiforme (GBM) who received Agenus' Prophage autologous cancer vaccine added to the standard of care treatment, lived nearly twice as long as expected.
Agenus Inc., a biotechnology company developing novel immune system activating treatments for cancers and infectious diseases, announced that Phase 2 results of Prophage G-200 vaccine in recurrent patients with glioblastoma multiforme were hailed as 'exciting' and a 'very promising therapy' in an editorial published in Neuro-Oncology, the leading journal of the Society of Neuro-Oncology.
Agenus Inc., a biotechnology company developing novel immune system activating treatments for cancers and infectious diseases, today announced results published from a Phase 2 study demonstrated that more than 90% of the patients treated with Prophage Series G-200 were alive at six months after surgery and 30% were alive at twelve months.
Two new studies, published in The Lancet and The Lancet Oncology, show that targeted radiotherapy delivered during surgery could offer a viable alternative to current procedures – which require women to attend daily radiotherapy sessions for weeks after surgery – for some women undergoing surgery for early breast cancer.
Proton therapy, an external beam radiotherapy in which protons deliver precise radiation doses to a tumor and spare healthy organs and tissues, is cost-effective in treating medulloblastomas, fast-growing brain tumors that mainly affect children, when compared to standard photon radiation therapy, according to research presented today at the American Society for Radiation Oncology's (ASTRO's) 55th Annual Meeting.