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New screening strategy identifies novel inhibitors that may help develop cure for Parkinson's

Parkinson's disease is the most common movement disorder in the world. PD patients suffer from shaking, rigidity, slowness of movement and have difficulties walking.

10 Sep 2018

Dr Maddy Parsons receives Royal Microscopical Society Life Science Medal

Dr Maddy Parsons, a Group Leader in the Randall Division of Cell & Molecular Biophysics, has been awarded the Royal Microscopical Society Life Science Medal for her outstanding scientific contribution to applying microscopy in the field of cell biology.

20 Jul 2018

Resolving Interfacial Protein Dynamics by STReM

STReM stands for Super Time-Resolved Microscopy, and as STORM, PALM, and other methods are designed to improve spatial resolution of optical microscopy, we desire to improve the time resolution. STReM makes use of point spread function engineering to encode fast events into each camera frame.

From Pittcon 16 Feb 2018

Economical Fluorescence Adapter for Stereo Microscopes

An interview with Charles Mazel, President of NIGHTSEA, conducted by Barbara Foster, The Microscopy & Imaging Place, Inc.

From NIGHTSEA 25 Jan 2018

RAS dimers essential for causing cancer, study shows

Mutated RAS genes are some of the most common genetic drivers of cancer, especially in aggressive cancers like pancreatic and lung cancer, but no medicines that target RAS are available despite decades of effort.

12 Jan 2018

In era of increased competition, hospitals fret over ratings

For two years, Saint Anthony Hospital here has celebrated its top-rated "A" grade from the national Leapfrog Group that evaluates hospital safety records. But this fall, when executives opened a preview of their score, they got an unwelcome surprise: a "C."

11 Dec 2017

Scientists one step closer to unraveling mystery of how intrinsically disordered proteins work

Determining how proteins function on a molecular level is crucial to understanding the underlying basis for disease. Now scientists at the University of Notre Dame are one step closer to unraveling the mystery of how intrinsically disordered proteins work, according to new research published in Science

13 Oct 2017

New technique quickly, economically monitors multiple molecular interactions in living tissues

A new approach to optical imaging makes it possible to quickly and economically monitor multiple molecular interactions in a large area of living tissue -- such as an organ or a small animal; technology that could have applications in medical diagnosis, guided surgery, or pre-clinical drug testing.

18 Aug 2017

Study: People with financial literacy less likely to fret about life in old age

People who possess a greater understanding of finance are less likely to fret about life in their twilight years.

17 Apr 2017

AXT introduces super-resolution fluorescence microscope capable of single molecule imaging in Australia and NZ

AXT are proud to announce that they have recently been appointed the exclusive Australian and New Zealand distributor for Oxford Nanoimaging (ONI). ONI is a UK-based company that has commercialised the “Nanoimager” a revolutionary super-resolution fluorescence microscope capable of single molecule imaging.

From AXT Pty Ltd 21 Mar 2017

Scientists map vast spider web of cancer proteins to reveal new drug targets

Scientists at Winship Cancer Institute of Emory University have mapped a vast spider web of interactions between proteins in lung cancer cells, as part of an effort to reach what was considered "undruggable."

17 Feb 2017

Naptime could have beneficial effect on language learning in preschool-age children

Research has shown that naps play an important role in sustaining new learning in infants. A new study from the University of Arizona suggests naptime could have a similar effect on language learning in preschool-age children.

8 Feb 2017

IBS scientists develop Nano MRI Lamp for smarter diagnosis of diseases

A research team led by CHEON Jinwoo at the Center for Nanomedicine, within the Institute for Basic Science, developed the Nano MRI Lamp: A new technology platform that tunes the magnetic resonance imaging signals "ON" only in the presence of the targeted disease.

6 Feb 2017

Elucidating IDP behaviour on crowded membranes

IDPs are proteins that contain stretches of amino-acid sequence that are flexible and do not comprise stable structure in isolation. This is in contrast with a more traditional view of proteins as largely occupying a stable native structure that correlates with functions such as enzyme activity or binding.

10 Nov 2016

FRET-FLIM imaging techniques help researchers to study activity of proteins in dendritic spines

An ongoing challenge for scientists working to understand the brain is being able to see all its parts. Researchers have spent centuries developing better imaging techniques to see beyond the abilities of our naked eyes.

2 Nov 2016

LJI researchers reveal unanticipated way by which neutrophils defend against invading pathogens

As an arm of the innate immune system, white blood cells called neutrophils form the first line of defense against invading pathogens.

31 Aug 2016

Researchers use FRET to make activation of AMPA receptors optically visible

Our brain is a high-performance computer. One of the key players in this complex system is the AMPA-type glutamate receptor. It ensures that neurotransmission proceeds at a breakneck pace from cell to cell.

6 Jul 2016

Scientists visualize apoptosis in live zebrafish using FLIM OPT method

A promising approach for watching cell signaling processes in their physiological context: Scientists visualize apoptosis in live zebrafish using fluorescence lifetime imaging with optical projection tomography to map FRET biosensor activity in space and time.

11 May 2016

Researchers use BMG LABTECH's microplate readers to measure binding events in kinetic over minutes

Single reading events of a signaling molecule at a given time should no longer be considered as the only insightful indicator to predict the usefulness of a new drug candidate.

From BMG LABTECH GmbH 19 Apr 2016

Versatile Automated Microplate Sample Screening Applications

In this interview, News Medical speaks Tobias Pusterla, Ph.D from BMG Labtech about versatile automated microplate sample screening applications.

From BMG LABTECH GmbH 30 Mar 2016