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Genetic data from an island population proves to be a useful tool in understanding disease

With fewer than 4,000 residents, the genetically isolated Micronesian island of Kosrae, in the West Pacific, provides an ideal population in which to research heritability of disease.

20 Apr 2006

Hap1 protein could lead to future drug targets for eating disorders

Researchers have discovered how the protein Hap1, which is abundant in the brain's hypothalamus, serves as the link between circulating insulin in the blood and the neural circuitry that controls feeding behavior in mice.

16 Apr 2006

Excessive adiposity, calorie restriction, and aging

Can eating a low-calorie yet nutritionally balanced diet extend human life? Preliminary research suggests it might, so researchers at Washington University School of Medicine in St. Louis are launching a long-term study to find out.

16 Apr 2006

Eat less, live longer!

According to researchers reducing calories may very well mean you have a longer life.

5 Apr 2006

Laughter is the best medicine

There's no doubt that laughter feels good, but is there real neurophysiology behind it and what can you do about it?

3 Apr 2006

Bariatric surgery may reduce risk of heart disease

"We believed the surgical patients would have a modest reduced risk, but instead we discovered there are significant and long-lasting heart benefits for this group," Dr. Batsis says.

21 Mar 2006

Diabetics shown to have increased heart muscle mass

Diabetes strongly increases the risk of heart failure in all ethnic groups, but early effects of diabetes on the heart may differ depending on whether the subjects are white, African-American, Hispanic or Chinese.

9 Mar 2006

Validation of cardiovascular risk scores in a liver transplant population

Two methods of assessing a patient's risk of cardiovascular events - SCORE and PROCAM - proved more valuable for liver transplant recipients than an alternative method, according to a new study.

7 Mar 2006

Amputation among patients with diabetes mellitus - increased risk of neuropathy and diabetic ulcers in taller patients

Patients with diabetes mellitus are at risk of leg ulcers. These eventually become infected, respond poorly to treatment and often require amputation of the foot or part of the leg.

7 Feb 2006

Diet rich in whole-grain foods may lower heart disease risk in elderly people

With the recent revision of the Food Guide Pyramid, the Dietary Guidelines for Americans have for the first time provided the public with a quantitative recommendation for whole-grain intake.

7 Feb 2006

Mechanism of torpor - hibernation-like state

If doctors could put people in hibernation and pull them out at will, scientists think they could minimize damage from strokes, help recipients' bodies accept transplanted organs, perhaps even enable astronauts to travel in suspended animation until reaching distant destinations.

7 Feb 2006

$More fractures, less bone density in premenopausal women with diabetes$

More fractures, less bone density in premenopausal women with diabetes

Premenopausal women who have type 1 diabetes should strongly consider preventive screening for osteoporosis, the researchers of a new study on bone density conclude in the February issue of Diabetes Care.

27 Jan 2006

Molecular disruption of hypothalamic nutrient sensing induces obesity

In their latest finding on the brain's role in controlling appetite and weight, researchers at the Albert Einstein College of Medicine have shown that reducing levels of fatty acids in the hypothalamus causes rats to overeat and become obese. Their results suggest that restoring fatty-acid levels in the brain may be a promising way to treat obesity.

16 Jan 2006

Gulf War Syndrome more prevalent in first Persian Gulf War veterans

Comparing veterans deployed in the first Persian Gulf War and veterans deployed elsewhere at the same time has revealed veterans who served in the Persian Gulf have nearly twice the prevalence of chronic multi-symptom illness (CMI), a cluster of symptoms similar to a set of conditions often called Gulf War Syndrome.

5 Jan 2006

Elevated homocysteine levels may be a biomarker for increased risk of AMD

People who have elevated homocysteine in their blood, an amino acid that is a known biomarker for cardiovascular disease, may also be at an increased risk of developing age-related macular degeneration (AMD), according to a study in the January issue of the American Journal of Ophthalmology.

5 Jan 2006