Fibrosis News and Research

RSS

Fibrosis is the growth of fibrous tissue.

Scientists discover new properties of imidazolium salts

Scientists at Singapore's Institute of Bioengineering and Nanotechnology (IBN) have uncovered new properties of imidazolium salts (IMSs), which suggest that they could play a vital role in disease prevention and treatment.

1 Dec 2008

Bariatric surgery may resolve liver disease

Obesity is a growing epidemic in the U.S. with a significant increase in prevalence from 15 percent to 32.9 percent from 1980 to 2004. Nonalcoholic fatty liver disease (NAFLD) is an emerging problem related to the obesity epidemic, becoming one of the most common causes of liver disease in the nation.

1 Dec 2008

Anadys Pharmaceuticals receives fast track for ANA598 treatment of chronic hepatitis C virus

Anadys Pharmaceuticals, Inc. has announced that the U.S. Food and Drug Administration (FDA) has granted fast track designation to ANA598 for the treatment of chronic hepatitis C virus (HCV) infection. ANA598 is Anadys' investigational hepatitis C non-nucleoside polymerase inhibitor.

1 Dec 2008

Noninvasive test for urine protein detects kidney dysfunction in transplant patients

A noninvasive test that analyzes proteins in the urine can correctly identify patients whose transplanted kidneys are failing, according to a study appearing in the February 2009 issue of the Journal of the American Society Nephrology (JASN).

26 Nov 2008

Nplate receives positive opinion for marketing authorisation in Europe

Amgen has announced that the European Committee for Medicinal Products for Human Use (CHMP) has issued a positive opinion recommending marketing authorisation for Nplate (romiplostim) in the European Union (EU).

21 Nov 2008

FDA approves GSK's Promacta (Eltrombopag)

GlaxoSmithKline has announced that the United States Food and Drug Administration (FDA) granted accelerated approval for PROMACTA (eltrombopag) for the treatment of thrombocytopenia in patients with chronic immune (idiopathic) thrombocytopenic purpura (ITP) who have had an insufficient response to corticosteroids, immunoglobulins or splenectomy.

20 Nov 2008

Altus Pharmaceuticals reaffirms plan to submit NDA for Trizytek

Altus Pharmaceuticals Inc. announced today that it is reaffirming its plan to submit a new drug application (NDA) for Trizytek TM (liprotamase) in the first-half of 2009.

18 Nov 2008

Researchers describe how cells recycle protein waste

Garbage collectors are important for removing trash; without them waste accumulates and can quickly become a health hazard.

11 Nov 2008

Acologix demonstrates improved bone architecture in rat model of chronic kidney disease

Acologix, Inc. will present data indicating that its therapeutic product candidate AC-200 improved bone architecture in a rat model of chronic kidney disease.

8 Nov 2008

Australian-led global initiative to improve diagnosis of genetic disorders

An Australian-led global initiative to improve the diagnosis of genetic disorders and reduce errors in the reporting of genetic variations has been published today in the prestigious scientific journal Science.

7 Nov 2008

Healing process found to backfire in idiopathic pulmonary fibrosis patients

A mechanism in the body which typically helps a person heal from an injury, may actually be causing patients with idiopathic pulmonary fibrosis (IPF) to get worse, researchers at the National Institute of Environmental Health Sciences (NIEHS), a part of the National Institutes of Health (NIH), and their collaborators have found.

27 Oct 2008

Universal test for genetic diseases in unborn children in the pipeline

A team of British scientists have developed a ground-breaking new test to screen for genetic diseases in unborn children.

27 Oct 2008

Simple gene-based blood test, quicker, more accurate evaluation for cystic fibrosis

Researchers at National Jewish Health have identified a simple gene-based blood test that more accurately and quickly measures cystic fibrosis patients' response to therapy than current tests.

26 Oct 2008

Resveratrol shows promise for treating human alcoholic fatty liver disease

The accumulation of fat in the liver as a result of chronic alcohol consumption could be prevented by consuming resveratrol, according to a new study with mice. The research found that resveratrol reduced the amount of fat produced in the liver of mice fed alcohol and, at the same time, increased the rate at which fat within the liver is broken down.

14 Oct 2008

Kamada reports positive data with inhaled Alpha-1 Antitrypsin in cystic fibrosis

Kamada has announced today positive data from its Phase II study evaluating inhaled Alpha-1 Antitrypsin (AAT) delivered via an Investigational eFlow Nebulizer System (PARI Pharma GmbH), in the treatment of cystic fibrosis. The results demonstrate the product has an excellent safety profile and shows promising signs of efficacy, as indicated by a reduction in lung inflammation.

12 Oct 2008

Children with cystic fibrosis not well covered by guidelines for vitamin D needs

Existing recommendations for treating vitamin D deficiency in children with cystic fibrosis (CF) are too low to cover the serious need, leaving most at high risk for bone loss and rickets, according to researchers at Johns Hopkins Children's Center.

12 Oct 2008

New pig model of cystic fibrosis provides better understanding of human disease

For the first time, researchers have developed a genetically altered animal model for cystic fibrosis (CF) that closely matches the characteristics of the disease in humans. By studying the complex and multi-organ disease process in the pig model, researchers can now better understand how the complications of CF develop, an advancement that may lead to new avenues for research in prevention and treatment.

25 Sep 2008

Some cases of breast cancer overtreated

According to a new study standard radiation therapy for some breast cancer patients may not be medically required and may, therefore, be causing unnecessary serious side effects.

24 Sep 2008

Protein opens hope of treatment for cystic fibrosis patients

Scientists have finally identified a direct role for the missing protein that leaves cystic fibrosis patients open to attack from lung-damaging bacteria, the main reason most of them die before their 35th birthday, scientists heard today (Thursday 11 September 2008) at the Society for General Microbiology's Autumn meeting being held this week at Trinity College, Dublin.

10 Sep 2008