Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

Potential new treatments for polycystic kidney disease

A family of small molecules called CFTR inhibitors show promising effects in slowing the progression of polycystic kidney disease (PKD), the most common genetic disease of the kidneys, according to preliminary research reported in the July 2008 issue of the Journal of the American Society Nephrology.

3 Apr 2008

Lung transplants not dangerous for children with cystic fibrosis, after all

Responding to a study published in the New England Journal of Medicine, which concluded that lung transplants were harmful for children with cystic fibrosis, articles published in the latest issue of Pediatric Transplantation refute the conclusions and argue that the highly influential research was severely flawed.

1 Apr 2008

Research leads to innovative therapies against cystic fibrosis

New U of T research holds promise for developing innovative therapies against cystic fibrosis and may also serve as a model for future therapies against the HIV virus.

19 Mar 2008

SnowWorld, an interactive, virtual-reality video game helps burn patients with pain relief

To a patient recovering from severe burns, no place would be more soothing than a polar landscape of gently falling snowflakes, snowmen, penguins, igloos and icy rivers.

19 Mar 2008

Long-term muscle improvements shown in gene therapy study in mice

Injecting a gene responsible for making a specific protein into a mouse that's used as a model for muscular dystrophy can lead to long-term improvements in the animal's muscle size and strength, a new study shows.

14 Mar 2008

Potential new gene therapy strategy for muscle-wasting diseases

Investigators in The Research Institute at Nationwide Children's Hospital have identified the role of a protein that could potentially lead to new clinical treatments to combat musculoskeletal diseases, including Duchenne muscular dystrophy (DMD).

11 Mar 2008

Long-term muscle improvements shown in gene therapy study in mice

11 Mar 2008

Improved method for genetically manipulating human embryonic stem cells

UC Irvine researchers have discovered a dramatically improved method for genetically manipulating human embryonic stem cells, making it easier for scientists to study and potentially treat thousands of disorders ranging from Huntington's disease to muscular dystrophy and diabetes.

10 Mar 2008

Serum fibrosis markers correlate with liver fibrosis stage in patients with advanced chronic hep C

A prospective study of patients with advanced chronic hepatitis C (CHC) revealed that a 3-variable model of serum fibrosis markers, including serum HA, TIMP-1 and platelet count, could identify cirrhosis with better accuracy than other published models.

4 Mar 2008

Discovery of key molecular mechanism associated with cystic fibrosis

Researchers from the University of North Carolina at Chapel Hill have identified a key molecular mechanism that may account for the development of cystic fibrosis.

4 Mar 2008

FzioMed's Oxiplex gel for spine surgery approved in Canada

FzioMed, Inc. (www.fziomed.com) has announced that Health Canada has approved the company's Oxiplex gel for use in lumbar spine surgery.

1 Mar 2008

Discovery of key molecular mechanism that may account for the development of cystic fibrosis

Researchers from the University of North Carolina at Chapel Hill have identified a key molecular mechanism that may account for the development of cystic fibrosis, which about 1 in 3000 children are born with in the US every year.

1 Mar 2008

Decline in cystic fibrosis since introduction of prenatal carrier screening

A brief report in the February 28, 2008, New England Journal of Medicine, led by researchers at the New England Newborn Screening Program (NENSP) of the University of Massachusetts Medical School (UMMS), indicates a declining incidence of a genetic disease, providing what may be the first demonstration of a link between two independent population-based screening programs.

28 Feb 2008

Technology to defeat bacterial infections shows positive results

The use of natural controls against serious bacterial infection and superbugs is being led by a UK company. Scientists at Biocontrol Ltd have presented at the Bacteriophage 2008 meeting in Hertfordshire a first look at the results of their initial Phase II clinical trial.

25 Feb 2008