Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

Exposure to secondhand smoke linked to worsening of lung function in cystic fibrosis sufferers

Exposure to secondhand smoke is associated with adverse effects on lung function among persons with cystic fibrosis, with this effect being worse for persons with certain gene variations, according to a study in the January 30 issue of JAMA.

31 Jan 2008

Lungs' mast cells could provide new treatment target for asthma, other respiratory disease

An enzyme released by mast cells in the lungs appears to play a key role in the tightening of airways that is a hallmark of asthma pointing to a potential new target for treatment against the illness.

30 Jan 2008

New target found for asthma

An enzyme released by mast cells in the lungs appears to play a key role in the tightening of airways that is a hallmark of asthma -- pointing to a potential new target for treatment against the illness.

29 Jan 2008

Adult stem cell application effective in treatment of peripheric vascular disease

Multipotent adult progenitor stem cells extracted from bone marrow, and known as MAPCs, have proved to be effective in the regeneration of blood vessel tissue and also in muscle tissue when treating peripheric vascular disease.

25 Jan 2008

Myostatin inhibitors may make injuries more likely

Block the action of a protein that normally regulates muscle mass, and watch your muscles grow.

23 Jan 2008

Debate over safety of gene therapy trials focuses on issue of informed consent

Can a patient who agrees to participate in a safety study of a gene therapy protocol give truly informed consent and understand the risks involved when the consent forms are highly technical and the physician or institution seeking their consent has a stake in the study and its outcome?

23 Jan 2008

New research finds way for wounds to heal without scars

The researchers from Bristol University believe their discovery has major implications not just for wound victims, but also for people who suffer organ tissue damage through illness or abdominal surgery.

22 Jan 2008

Minute genetic differences have major consequences

A study led by McGill University researchers has demonstrated that small differences between individuals at the DNA level can lead to dramatic differences in the way genes produce proteins.

21 Jan 2008

Case researcher in RNA biology makes waves by challenging current thinking

In the January 18th issue of Molecular Cell, Case Western Reserve University School of Medicine researcher Kristian E. Baker, Ph.D. challenges molecular biology's established body of evidence and widely-accepted model for nonsense-mediated messenger ribonucleic acid (mRNA) decay.

21 Jan 2008

Rare lung disease cells indicate higher death risk

Large numbers of certain cells in the lungs of patients diagnosed with idiopathic pulmonary fibrosis may increase their chance of death, University of Cincinnati (UC) researchers have discovered.

17 Jan 2008

Extra-hepatic manifestation of hepatitis C virus infection

In 1994, the team of Tchernev and Petrova from Alexandrovska Hospital in Sofia examined a female patient with liver cirrhosis caused by chronic Hepatitis C virus (HCV).

17 Jan 2008

Smoking belies milder disease but worse prognosis for idiopathic pulmonary fibrosis patients

Smokers and ex-smokers with idiopathic pulmonary fibrosis (IPF), an untreatable progressive lung disease that usually leads to death within a few years of diagnosis, have a worse prognosis than non-smokers, according to research from London.

16 Jan 2008

Fish oil supplements may help some cardiac patients while harming others

Fish oil supplements may help some cardiac patients while harming others, suggests a new review of evidence compiled by St. Michael's Hospital and University of Toronto researchers.

15 Jan 2008

A look at China's most innovative health biotechnology companies

Government funds innovation but venture capital needed; Wary investors 'need to be shown the exits'; Returning 'sea turtles' bring expertise, international credibility

8 Jan 2008

MRI techniques evolving towards better assessment of liver fibrosis

MRI imagery is emerging as a non-invasive way to determine the existence and extent of hepatic fibrosis.

3 Jan 2008

Highlights of pulmonary and critical care symposium

New perspectives on lung cancer screening, complications of sleep apnea, cystic fibrosis, and other key topics in pulmonary and critical care medicine are presented in the special January issue of The American Journal of Medical Sciences, published by the Southern Society for Clinical Investigation and Lippincott Williams & Wilkins, a part of Wolters Kluwer Health, provider of leading healthcare content, context and consulting.

3 Jan 2008

Allergic reactions to gadolinium-containing contrast injections - study

Allergic-like reactions to gadolinium-containing contrast injections in adults and pediatric patients (those younger than 19 years of age) are rare, according to a recent study conducted by researchers at the University of Michigan Health Systems in Ann Arbor.

2 Jan 2008

Optimal therapy for U.S. hepatitis C patients

As reported recently in the journal Hepatology, WIN-R, a multicenter study of over 5,000 patients with hepatitis C virus (HCV) showed treatment with weight-based REBETOL ribavirin, USP) (RBV) in combination with pegylated interferon (PEG-IFN) alfa-2b achieved significantly higher rates of sustained virologic response (SVR) and lower relapse rates compared to combination therapy using a flat dose of RBV 800 mg/day. Superior response was found particularly in patients with the most difficult-to-treat form of the disease, genotype 1 HCV. Efficacy was consistent across all weight groups.

28 Dec 2007