Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

Study shows how antibiotic gentamicin affects cystic fibrosis patients with a stop mutation

Genetics tests could help provide cystic fibrosis (CF) patients with targeted treatment in future, pilot study authors suggest.

30 Mar 2007

Molecular mechanism involved in development of schizophrenia

In studying the postmortem brain tissue of adults who had been diagnosed with schizophrenia, the researchers found that levels of certain gene-regulating molecules called microRNAs were lower among schizophrenia patients than in persons who were free of psychiatric illness.

30 Mar 2007

Trojan horse approach designed to defeats drug-resistant bacteria

A new antimicrobial approach can kill bacteria in laboratory experiments and eliminate life-threatening infections in mice by interfering with a key bacterial nutrient, according to research led by a University of Washington scientist.

19 Mar 2007

Newborns with respiratory distress should be evaluated for primary ciliary dyskinesia

Reviewing published reports, Ferkol and Margaret Leigh, M.D., professor of pediatrics at the University of North Carolina at Chapel Hill (UNC), found that neonatal respiratory distress was a common clinical symptom of PCD, a chronic airway disease that affects about 1 in 15,000 children.

20 Feb 2007

Mechanism driving iron overload in thalassemia identified

Led by researchers at Weill Cornell Medical College in New York City, an international group of scientists has pinpointed a specific genetic relationship as the cause of dangerous iron overload in persons with a form of the inherited blood disease, beta-thalassemia.

14 Feb 2007

New diagnostic technology for routine prenatal genetic testing

Research studies demonstrating the viability of an approach to routinely detect the presence of fetal DNA in a mother's blood to accurately diagnose or rule out genetic defects -- as early as the first trimester -- was presented today at the 27th Annual Meeting of the Society for Maternal-Fetal Medicine being held in San Francisco.

11 Feb 2007

Antipodean Pharma commences phase 2 trial in hepatitis C

Antipodean Pharmaceuticals has announced it has initiated a Phase 2 clinical trial of its lead compound MitoQ (mitoquinone) to investigate the drug's efficacy to reduce liver damage in patients with raised liver enzymes associated with the Hepatitis C virus (HCV).

5 Feb 2007

Garlic offers hope in cystic fibrosis infection

Garlic has been hailed a wonder drug for centuries and has been used to prevent gangrene, treat high blood pressure, ward off common colds and is even believed by some to have cancer-fighting properties.

31 Jan 2007

Link between MRI contrast agent and nephrogenic systemic fibrosis

New research has shown a possible association between a popular magnetic resonance imaging (MRI) contrast agent and the incidence of a rare disease called nephrogenic systemic fibrosis (NSF) in patients with kidney disease, according to an editorial appearing in the March issue of Radiology.

28 Jan 2007

Lung neutrophils produce histamine in significant quantities

In a surprise finding, scientists have discovered that histamine, the inflammatory compound released during allergic reactions that causes runny nose, watery eyes, and wheezing, can be produced in large amounts in the lung by neutrophils, the white blood cells that are the major component of pus.

14 Jan 2007

Elasticity imaging could alleviate need for biopsies

A noninvasive technique to visualize soft tissue stiffness allows radiologists to accurately distinguish benign from malignant breast lesions.

2 Dec 2006

Liver damage can be reversed

Saint Louis University Liver Center scientists are presenting research today on a more effective way to treat hepatitis C patients who have been unresponsive to current drug therapies.

30 Oct 2006

Expert says flu vaccination programs a pointless waste of money

According to a vaccine expert the millions spent on flu vaccination programs each year are a waste of time and money.

30 Oct 2006

WHO unveils new strategy to fight some of the most neglected tropical diseases

The World Health Organization (WHO) and a group of more than 25 partner organizations unveiled a new strategy to fight some of the most neglected tropical diseases that destroy the lives and health of poor people.

26 Oct 2006

New compounds could make drug-resistant bacteria harmless

Just as the medical world has become concerned over the apparent resistance of some bugs to antibiotics, scientists have made significant progress towards the development of a new generation of antibiotics.

12 Sep 2006

Colchicine delays development of hepatocellular carcinoma in patients with hepatitis virus-related liver cirrhosis

Colchicine, an anti-inflammatory drug most often used to treat gout, prevented liver cancer in patients with hepatitis virus-related end-stage liver disease, according to a new study.

11 Sep 2006

UIC receives $20 million NCI grant to research blood disorders

A $19.6 million National Cancer Institute grant has been awarded to the University of Illinois at Chicago College of Medicine to advance basic and clinical research for incurable blood disorders.

6 Sep 2006

Immunotherapy for heart failure

World Congress of Cardiology Report - Heart failure (HF) is a complex, progressive clinical syndrome that can result from any structural or functional cardiac disorder, such as coronary artery disease or hypertension (high blood pressure), which impairs the ability of the heart to function properly as a pump.

5 Sep 2006

Prenatal diagnostic tests have low risk of miscarriage

Pregnant women who seek prenatal diagnostic testing to identify genetic or chromosomal abnormalities have a lower risk of miscarriage than previously believed, according to a UCSF study.

31 Aug 2006