Finasteride News and Research

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Finasteride is a synthetic antiandrogen which acts by inhibiting type II 5-alpha reductase, the enzyme that converts testosterone to dihydrotestosterone (DHT). It is used as a treatment in benign prostatic hyperplasia (BPH) in low doses, and prostate cancer in higher doses. Finasteride competitively binds to and inhibits steroid type II 5-alpha-reductase in the prostate gland, liver, and skin, thereby interfering with the enzymatic conversion of testosterone to 5-dihydrotestosterone (DHT) and reducing serum DHT levels. The reduction in serum DHT levels results in diminished stimulation of androgen receptors in the nuclei of prostate cells and, so, diminished prostate cell proliferation.
Study describing solid-state characterization of three forms of finasteride published

Study describing solid-state characterization of three forms of finasteride published

"Hotline" report on finasteride for prevention of prostate cancer

"Hotline" report on finasteride for prevention of prostate cancer

Tips for treating age-related dermatologic concerns

Tips for treating age-related dermatologic concerns

New tools needed to identify men and women at risk for the most aggressive cancers

New tools needed to identify men and women at risk for the most aggressive cancers

Symposium on genetics of psoriasis and psoriatic arthritis to be held

Symposium on genetics of psoriasis and psoriatic arthritis to be held

Prostate cancer: current evidence weighs against population screening

Prostate cancer: current evidence weighs against population screening

Selenium and vitamin E supplements do not prevent prostate cancer

Selenium and vitamin E supplements do not prevent prostate cancer

Vitamin E and selenium do not prevent prostate cancer

Vitamin E and selenium do not prevent prostate cancer

Finasteride for prostate cancer

Finasteride for prostate cancer

Five-alpha-reductase Inhibitors for prostate cancer prevention

Five-alpha-reductase Inhibitors for prostate cancer prevention

Heart-healthy diet may also be good for the prostate

Heart-healthy diet may also be good for the prostate

Pros, cons of finasteride to prevent prostate cancer should be considered

Pros, cons of finasteride to prevent prostate cancer should be considered

Coping with urinary incontinence

Coping with urinary incontinence

Prostate cancer prevention: past, present, and future

Prostate cancer prevention: past, present, and future

Diet and medications may assist prevention of prostate cancer

Diet and medications may assist prevention of prostate cancer

Shrinkage of prostate led to overestimation of cancer risk in finasteride trial

Shrinkage of prostate led to overestimation of cancer risk in finasteride trial

Generic prostate drug finasteride helps find high-risk cancers early

Generic prostate drug finasteride helps find high-risk cancers early

Finasteride unlikely to induce high grade prostate cancers

Finasteride unlikely to induce high grade prostate cancers

Finasteride will cause little or no sexual dysfunction for most men who decide to take it

Finasteride will cause little or no sexual dysfunction for most men who decide to take it

A review of PSA use in screening for prostate cancer

A review of PSA use in screening for prostate cancer