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New test rapidly determines neutralizing antibodies against Sars-Cov-2

To determine immunity to Sars-Cov-2 and the effectiveness of potential vaccines, the amount of neutralizing antibodies in the blood of recovered or vaccinated individuals must be determined.

30 Jul 2020

Scientists develop human lung organoids to study SARS-CoV-2 infection

Now, a new study published on the preprint server bioRxiv in July 2020 reports the development of a human distal lung culture system that can be functionally tested. This will help not only to understand how this infection produces disease but also to test the proliferative capacity of the stem cells in this part of the body.

30 Jul 2020

Study offers fundamental insights about sensory thalamic subnetworks

The thalamus is a "Grand Central Station" for sensory information coming to our brains. Almost every sight, sound, taste and touch we perceive travels to our brain's cortex via the thalamus.

23 Jul 2020

Pioneering method reveals the dynamics of HIV Gag lattice structure

Viruses are scary. They invade our cells like invisible armies, and each type brings its own strategy of attack. While viruses devastate communities of humans and animals, scientists scramble to fight back.

16 Jul 2020

Study reveals a new way to determine the age of insulin-storage parcels

A study in the Journal of Biological Chemistry describes a new way to determine the age of insulin-storage parcels, known as granules, and sheds light on how their age affects their release into the bloodstream.

7 Jul 2020

Clemson researcher receives DOD grant to explore cellular underpinnings of developmental disorder

College of Science associate professor and researcher David Feliciano has received a $667,000 grant from the Department of Defense to explore the cellular underpinnings of Tuberous Sclerosis Complex (TSC), a developmental disorder characterized by the growth of benign tumors throughout the body, most notably in the brain.

6 Jul 2020

Remodeling may make neurons more prone to Alzheimer's disease

Neurons that regularly remodel are more prone to Alzheimer's disease and die when that remodeling goes awry, a new study suggests. The work is the first to track the progression of Alzheimer's at the genetic and molecular levels within neurons vulnerable to the disease.

29 Jun 2020

MIT engineers create a focused approach to imaging neural activity

When neurons fire an electrical impulse, they also experience a surge of calcium ions. By measuring those surges, researchers can indirectly monitor neuron activity, helping them to study the role of individual neurons in many different brain functions.

26 Jun 2020

Unique antiviral action of cholesterol 25-hydroxylase against SARS-CoV-2

A new study by U.S. and Chinese researchers, currently available on the bioRxiv* preprint server, demonstrates how cholesterol 25-hydroxylase and its enzymatic product 25-hydroxycholesterol can inhibit membrane fus

10 Jun 2020

Researchers grow lung organoids from stem cells for Sars-Cov-2 research

A Bochum-based team intends to use organoids from stem cells to study the progression of Sars-CoV-2 infection and to identify antiviral substances.

28 May 2020

Harmful effects of BPA can be reversed by administering coenzyme Q10

Exposure to bisphenol A (BPA), an industrial chemical used to make certain plastics and resins, inner coatings for food cans and bottle tops, thermal paper used in store receipts, dental sealants and so on, is a concern because of possible adverse health effects, including a reduction in fertility.

7 May 2020

New technique for imaging proteins in 3D

A team of scientists including researchers at the National Synchrotron Light Source II (NSLS-II)--a U.S. Department of Energy Office of Science User Facility at DOE's Brookhaven National Laboratory--have demonstrated a new technique for imaging proteins in 3-D with nanoscale resolution.

13 Apr 2020

Tracking tau protein yields insight into possible treatments for neurodegenerative diseases

In the fight against neurodegenerative diseases such as frontotemporal dementia, Alzheimer's and Chronic Traumatic Encephalopathy, the tau protein is a major culprit.

1 Apr 2020

A genetic toolkit to produce multifunctional magnetic nanoparticles

Magnetic bacteria might soon be used for the production of novel biomaterials. A team of microbiologists at the University of Bayreuth led by Prof. Dr. Dirk Schüler developed a modular system for the genetic reprogramming of bacteria, thereby turning the organisms into cell factories for multifunctional magnetic nanoparticles that combine various useful functions and properties.

25 Mar 2020

New insights may guide design of light-sensitive proteins with desired properties

A team of scientists from the Department of Energy's SLAC National Accelerator Laboratory and Stanford University has gained insight into how electric fields affect the way energy from light drives molecular motion and transformation in a protein commonly used in biological imaging.

13 Feb 2020

Macrophages migrate from the blood to attack brain tissue shortly after stroke

Macrophages are part of the innate immune system and essential for brain development and function. Using a novel method, scientists from Jena University Hospital, the University of Bonn and the Memorial Sloan Kettering Cancer Center in New York (USA) succeeded in visualizing macrophages that were formed in the bone marrow.

11 Feb 2020