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UVA, Johns Hopkins receive NIH grant to develop methods against glioblastoma

The most common primary brain cancer is glioblastoma, a highly aggressive and deadly form of tumor that kills about 95 percent of its victims within five years of diagnosis. Like other brain cancers, it is extremely difficult to treat because glioblastomas are usually deeply embedded within healthy brain tissue and therefore nearly impossible to safely access. Chemotherapy drugs cannot reach these tumors because a membrane between the bloodstream and brain tissue, called the blood-brain barrier, blocks them.

29 Feb 2012

Baxter commences CD34+ stem cell phase III trial in CMI

Baxter International Inc. announced today that it has initiated a phase III pivotal clinical trial to evaluate the efficacy and safety of adult autologous (an individual's own) CD34+ stem cells to increase exercise capacity in patients with chronic myocardial ischemia (CMI).

From Baxter International Inc. 28 Feb 2012

FDA issues complete response letter for Watson's progesterone vaginal gel 8% NDA

Watson Pharmaceuticals, Inc. and Columbia Laboratories, Inc. today confirmed that, as expected, Watson has received a complete response letter from the U.S. Food and Drug Administration (FDA) for its New Drug Application (NDA 22-139) for progesterone vaginal gel 8% for use in the reduction of risk of preterm birth in women with a singleton gestation and a short uterine cervical length in the mid-trimester of pregnancy.

27 Feb 2012

ATI commences European trial of neurostimulation system for migraine

Autonomic Technologies, Inc. (ATI), the developer of a novel miniaturized implantable stimulator for severe headaches, today announced initiation of a study in Europe to evaluate the safety and efficacy of the company's investigational neurostimulation system for the treatment of high frequency, high disability migraine.

27 Feb 2012

Kidney failure patients may benefit from frequent and longer dialysis treatments

Frequent and longer dialysis treatments may provide more benefits for patients than conventional dialysis treatments, according to several studies appearing in upcoming issues of the Journal of the American Society Nephrology.

24 Feb 2012

Older physicians have higher frequency of litigation

A Canadian study published in the March issue of Anesthesiology found that there was a higher frequency of litigation and a greater severity of patient injury associated with those litigations when the anesthesiologist was 65 years of age or older.

23 Feb 2012

Self-propelled devices through the bloodstream a reality

Someday, your doctor may turn to you and say, "Take two surgeons and call me in the morning." If that day arrives, you may just have Ada Poon to thank.

23 Feb 2012

Key regulator of lens development also controls mechanosensory neuron development

A gene known to control lens development in mice and humans is also crucial for the development of neurons responsible for mechanosensory function, as neurobiologists of the Max Delbr-ck Center for Molecular Medicine (MDC) Berlin-Buch have now discovered.

22 Feb 2012

DPN similar in prediabetic patients and healthy people

In a reversal of two decades of medical reports, a Mayo Clinic study finds the frequency of nerve damage called diabetic polyneuropathy is similar in prediabetic patients and healthy people. Physicians should seek explanations other than prediabetes for patients who have painful small fiber polyneuropathy, the researchers say.

21 Feb 2012

Work place carcinogens responsible for 5,000 cases of cancer annually

According to researchers carcinogens in the workplace are causing about 5,000 cancers each year and medical experts say not enough is being done to reduce the risks.

21 Feb 2012

Researchers track structural changes during formation of new memories

New connections between brain cells emerge in clusters in the brain as animals learn to perform a new task, according to a study published in Nature on February 19 (advance online publication). Led by researchers at the University of California, Santa Cruz, the study reveals details of how brain circuits are rewired during the formation of new motor memories.

20 Feb 2012

Smoke forecasting tools can help protect individuals and public health professionals

Satellite images, air quality measurements and smoke forecasting models are useful tools to help individuals and public health professionals prepare for smoke episodes in areas at risk from forest fire smoke, according to University of British Columbia researcher Michael Brauer.

20 Feb 2012

Increased bacterial loads in potable water may have significant health effects on indigenous people

Indigenous people around the world are among the most vulnerable to climate change and are increasingly susceptible to the pathogen loads found in potable water after heavy rainfall or rapid snow melt.

18 Feb 2012

ACAAI allergists available to discuss risks associated with asthma

The tragic death of journalist Anthony Shadid due to asthma and allergies underscores the realities of these serious diseases. Allergists Stanley Fineman, MD, president of the American College of Allergy, Asthma and Immunology, (ACAAI), and James Sublett, MD, chair of the ACAAI Environment Committee are available to discuss the risks associated with asthma.

18 Feb 2012

Study examines mercury exposure in pregnant women

A new study published by researchers at SUNY Downstate Medical Center's School of Public Health assesses mercury levels in pregnant women and examines dietary and environmental sources of exposure to mercury. The research, which focuses on an urban immigrant community, examined risk factors that may be associated with elevated mercury levels, measured through urine and cord blood samples.

18 Feb 2012

Study reveals new guiding principles for cancer genomics

That our chromosomes can break and reshuffle pieces of themselves is nothing new; scientists have recognized this for decades, especially in cancer cells. The rules for where chromosomes are likely to break and how the broken pieces come together are only just now starting to come into view.

17 Feb 2012

Study: 3D organization of chromosomes plays a role in cancer genomics

It is well understood that chromosomal translocation - a process whereby pieces of two chromosomes break off and exchange places - is a hallmark of many cancers including leukemia, thyroid cancer and lymphoma and play an important part in how healthy cells become cancerous. The role spatial proximity plays in why certain chromosomal translocations happen repeatedly, however, has been a long-standing area of debate among scientists.

17 Feb 2012

Augmented toys may help children with autism

Making play sets more interactive and giving children with autism greater opportunities to control and add content of their own to the game could improve cooperative play with other children as well as giving them greater confidence in understanding how objects interact.

17 Feb 2012

UC San Diego offers catheter ablation for patients with atrial fibrillation

UC San Diego Sulpizio Cardiovascular Center is now offering patients with atrial fibrillation the breakthrough benefits of heat energy, or radio frequency waves, to irreversibly alter heart tissue that triggers an abnormal heart rhythm or arrhythmia.

17 Feb 2012

Mediterranean diet could prevent brain damage in the long term: Study

A new study suggests that people who follow a Mediterranean-style diet have less small blood vessel damage in the brain. The study appeared in the February issue of the Archives of Neurology.

15 Feb 2012