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Gene therapy effectively stabilizes progression of cerebral adrenoleukodystrophy, trial reveals

In a recent clinical trial, a gene therapy to treat cerebral adrenoleukodystrophy (CALD) -- a neurodegenerative disease that typically claims young boys' lives within 10 years of diagnosis -- effectively stabilized the disease's progression in 88 percent of patients, researchers from the Dana-Farber/Boston Children's Cancer and Blood Disorders Center and Massachusetts General Hospital report today.

4 Oct 2017

Fructose plays more damaging role than glucose in fatty liver disease, mice study shows

If you're one of the two billion people in the world who are over-weight or obese, or the one billion people with fatty liver disease, your doctor's first advice is to cut calories-;and especially to cut down on concentrated sugars such as high-fructose corn syrup, a sugar found in sweetened beverages and many other processed foods.

4 Oct 2017

Highly elastic surgical glue quickly seals wounds without need for staples or sutures

A highly elastic and adhesive surgical glue that quickly seals wounds without the need for common staples or sutures could transform how surgeries are performed.

4 Oct 2017

Tulane researchers explore Shox2 protein’s potential link to epilepsy, autism and schizophrenia

Tulane University's Laura Schrader, a cell and molecular biology professor and Brain Institute member, received a two-year grant from the National Institute of Health to study the role of a Shox2, a protein in the brain important for development and function of the thalamus.

4 Oct 2017

UAlberta researchers create new imaging agents to keep track of tumor growth

UAlberta researchers have created two new imaging agents that could help physicians visualize the formation of tumor-associated blood vessels, keep track of tumor growth and possibly generate new therapies.

4 Oct 2017

Inexpensive soy filters could lead to better air purification

Air pollution is a major public health issue worldwide. Filters can help improve the quality of the air we breathe, but they also contribute to landfill when they are finished with and thrown away, as they are often made of plastic.

4 Oct 2017

Lower meat consumption during pregnancy increases risk of substance misuse by offspring

Lower meat consumption by women during pregnancy was linked with an increased risk of substance misuse by their children during adolescence. The findings come from a study published in Alcoholism: Clinical and Experimental Research.

4 Oct 2017

Scientists manipulate living cells to produce fluorinated bioplastics

Natural organic compounds that contain fluorine are rare because living organisms—with a few exceptions—do not produce them.

4 Oct 2017

CRISPR-Gold corrects gene mutations in mice with Duchenne muscular dystrophy

Scientists at the University of California, Berkeley, have engineered a new way to deliver CRISPR-Cas9 gene-editing technology inside cells and have demonstrated in mice that the technology can repair the mutation that causes Duchenne muscular dystrophy, a severe muscle-wasting disease.

4 Oct 2017

Novel agents appear to halt growth and progression of Ewing sarcoma

When combined with an already FDA-approved chemotherapy, a novel agent developed by researchers at Georgetown Lombardi Comprehensive Cancer Center, appears to halt the ability of Ewing sarcoma to grow and progress.

4 Oct 2017

Researchers provide new insights into how calcium signals trigger wound healing

In a sharp and pointy world, wound healing is a critical and marvelous process. Despite a tremendous amount of scientific study, many outstanding mysteries still surround the way in which cells in living tissue respond to and repair physical damage.

3 Oct 2017

Scientists unravel mechanism that links gut bacteria to hypertension

One in three American adults suffers from high blood pressure, or hypertension. The disease can be passed down in families, and certain lifestyle factors such as smoking, high-sodium diets, and stress can increase the risk.

3 Oct 2017

Researchers develop novel blood analyzer to improve anemia detection

About one quarter of the world's population suffers from anemia, a disease caused by a concentration deficiency of hemoglobin in red blood cells. To reduce the burden of anemia, health officials need a better picture of the disease's global impact, an understanding made viable by a portable and affordable way to analyze blood.

3 Oct 2017

Researchers identify new cancer-causing pathway behind most aggressive type of leukemia

A team led by Massachusetts General Hospital (MGH) investigators has identified a new cancer-causing pathway behind most cases of an aggressive type of leukemia, findings that could lead to new targeted treatment approaches.

3 Oct 2017

Studies shed new light on leading cause of birth defects and miscarriage

Two recent Northwestern University studies shed new light on the mystery of the leading cause of birth defects and miscarriage, laying the foundation for further research in an understudied but crucially important field of genetic study.

3 Oct 2017

New video shows benefits of VIAFLO 96/384 microplate pipettes

INTEGRA continues to place itself at the forefront of pipetting technology, developing and perfecting its VIAFLO 96/384 range of microplate pipettes for a variety of applications, including ELISA, PCR, and nucleic acid and protein extraction.

From INTEGRA Biosciences 3 Oct 2017

Estrogen acts as upstream regulator for energy metabolism and muscle cell viability, study finds

According to a research conducted at the University of Jyväskylä, estrogen acts as a regulator of muscle energy metabolism and muscle cell viability. Menopause leads to the cessation of ovarian estrogen production concurrent to the deterioration of muscle function.

3 Oct 2017

“Chemical surgery” on embryos to free them of a gene causing thalassemia

A team of Chinese researchers have for the first time “mended” defective embryos using chemical surgery to free them of a faulty gene that leads to beta thalassemia. Until now this defect was found to be incorrigible caused due to a single misspelling in the DNA code. Beta thalassemia is a dreaded blood disorder wherein the child is unable to make healthy blood needing blood transfusions on a regular basis. The study was published this week in the journal Protein and Cell.

2 Oct 2017

NsXeR protein: A new optogenetic tool to control muscle and neuronal cells

Scientists have examined a protein that will find application in optogenetics and could be used to control muscle and neuronal cells. The paper on the light-sensitive NsXeR protein of the xenorhodopsin class was published in Science Advances by the international team of researchers from MIPT, Research center Jülich, and Institut de Biologie Structurale.

30 Sep 2017

Researchers produce fluorinated molecules in living cells

Natural organic compounds that contain fluorine are rare because living organisms—with a few exceptions—do not produce them. American scientists have now genetically engineered a microbial host for organofluorine metabolism, allowing it to produce a fluoridated intermediate known as a diketide.

30 Sep 2017