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Study: Cellular housekeeping can help mammals live longer and healthier

Building on two decades of research, investigators at UT Southwestern have determined that "cellular housekeeping" can extend the lifespan and healthspan of mammals.

31 May 2018

Researchers trigger natural defense mechanism to alleviate intestinal inflammation

Treating inflammatory diseases of the bowel is extremely challenging: Genes, gut microbes and disrupted immune function all contribute.

31 May 2018

Study provides guidance to determine the right treatment for Red Diaper Syndrome

A case study and subsequent literature review has concluded that absent signs of clinical infection, breastfeeding should continue normally when mother and baby are diagnosed with Red Diaper Syndrome caused by Serratia marcescens, an opportunistic bacteria.

30 May 2018

CDC interventions targeting gestational diabetes may help mitigate risks for mother and baby

Diabetes in pregnant women can have serious health consequences for both mother and baby, and the U.S. Centers for Disease Control and Prevention has identified four target areas in which increased surveillance, screening, and preventive care can improve maternal and infant health.

29 May 2018

Bioethicist: 'Right to Try Act' will not benefit terminally-ill patients

Gregory Pence, Ph.D., professor and Chair of Philosophy, teaches bioethics at the University of Alabama at Birmingham.

26 May 2018

Scientists create small, self-contained spaces inside mammalian cells

How to install new capabilities in cells without interfering with their metabolic processes? A team from the Technical University of Munich and the Helmholtz Zentrum München have altered mammalian cells in such a way that they formed artificial compartments in which sequestered reactions could take place, allowing the detection of cells deep in the tissue and also their manipulation with magnetic fields.

23 May 2018

Small part of cellular protein that helps form long-term memories also drives neurodegeneration

Scientists have just discovered that a small region of a cellular protein that helps long-term memories form also drives the neurodegeneration seen in Amyotrophic Lateral Sclerosis (ALS). This small part of the Ataxin-2 protein thus works for good and for bad.

23 May 2018

Proteins moderating nicotine dependence may help fat cells burn energy

The same proteins that moderate nicotine dependence in the brain may be involved in regulating metabolism by acting directly on certain types of fat cells, new research from the University of Michigan Life Sciences Institute shows.

22 May 2018

Neurological protein found to protect against inflammatory diseases

Researchers have identified a protein involved in the activation of macrophages that protects against inflammatory disorders such as sepsis and inflammatory bowel disease.

21 May 2018

Scientists discover how unusually long strands of RNA help colon cancer cells avoid death

Researchers from Case Western Reserve University School of Medicine have discovered how unusually long strands of RNA help colon cancer cells avoid death, allowing unregulated growth.

17 May 2018

New study could have important implications for cellular aging

Researchers have found a way to stimulate autophagy, a process used by cells to convert misfolded proteins and redundant organelles into components that the cell can re-use.

16 May 2018

Researchers demonstrate new strategy for stimulating autophagy

Brown University researchers studying the biology of aging have demonstrated a new strategy for stimulating autophagy, the process by which cells rebuild themselves by recycling their own worn-out parts.

16 May 2018

Researchers to explore how to prevent stress-related chronic pain conditions

More than 50 million people in the United States suffer from pain in the absence of injury. This includes patients with migraines, fibromyalgia, irritable bowel syndrome and many other disorders.

15 May 2018

Study uncovers promising new line of attack against aggressive prostate cancer

UC San Francisco researchers have discovered a promising new line of attack against lethal, treatment-resistant prostate cancer. Analysis of hundreds of human prostate tumors revealed that the most aggressive cancers depend on a built-in cellular stress response to put a brake on their own hot-wired physiology.

14 May 2018

Heart failure severity could vary based on the body's nitric oxide levels

The most common heart medications may get an assist from nitric oxide circulating in the body, according to a new study out of Case Western Reserve University School of Medicine.

14 May 2018

Researchers urge re-examination of colonial models in regulation of traditional medicine practitioners

Two commentaries in JACM, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers that is dedicated to examining paradigm, practice, and policy advancing integrative health, raise questions about whether the value to health care of traditional, complementary, and integrative practices and practitioners is unfairly de-valued by the dominant biomedical model.

14 May 2018

New case study shows CAR T therapy as viable option for AML patients

Chimeric Antigen Receptor T-cell therapy, also known as CAR T therapy, was named the biggest research breakthrough of 2017 by the American Society of Clinical Oncology. The personal gene therapy utilizes a patient's own immune cells to fight cancer.

9 May 2018

Johns Hopkins researchers identify protein clumps in diseased hearts

Similar to how protein clumps build up in the brain in people with some neurodegenerative diseases such as Alzheimer's and Parkinson's diseases, protein clumps appear to accumulate in the diseased hearts of mice and people with heart failure, according to a team led by Johns Hopkins University researchers.

9 May 2018

Experts discuss how medicinal cannabis can impact opioid crisis

A multidisciplinary panel of experts discussed how medicinal cannabis can impact the opioid crisis, though clinical research to quantify this is difficult given strict federal laws

9 May 2018

New tool to track interactions among brain cells in action

It's a neuroscientist's dream: being able to track the millions of interactions among brain cells in animals that move about freely, behaving as they would under natural circumstances. New technology developed at The Rockefeller University represents a big step toward realizing that goal.

7 May 2018