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Impaired DNA replication may lead to trans-generational inheritance of epigenetic changes

Scientists reveal that a fault in the process that copies DNA during cell division can cause epigenetic changes that may be inherited for up-to five generations.

17 Aug 2017

Research shows how glutamine plays role in regulating cellular differentiation programs

The 200 different types of cells in the body all start with the same DNA genome. To differentiate into families of bone cells, muscle cells, blood cells, neurons and the rest, differing gene programs have to be turned on or off.

17 Aug 2017

Liquid biopsies show potential use for cancer screening

A new study has shown the potential of analyzing cell-free DNA (cfDNA) present in patients’ blood for cancer markers in early cancer detection. This technique was used in some instances for patients who already were diagnosed with a cancer as reported by some studies.

16 Aug 2017

Study offers novel insights into how genetic variants play key role in human immune system

It is widely recognized that people respond differently to infections. This can partially be explained by genetics, shows a new study published today in Nature Communications by an international collaboration of researchers from Germany and the United States.

16 Aug 2017

Lab-grown miniature blood vessels mimic rare Hutchinson-Gilford Progeria Syndrome

Biomedical engineers have grown miniature human blood vessels that exhibit many of the symptoms and drug reactions associated with Hutchinson-Gilford Progeria Syndrome -- an extremely rare genetic disease that causes symptoms resembling accelerated aging in children.

16 Aug 2017

Researchers develop and validate new assay that detects gene fusions in solid tumors

An assay that identifies a peculiar but important abnormality in cancer cells has been developed and validated by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

14 Aug 2017

Study shows how breast cancer cells spread late in disease development

Breast cancer cells that spread to other parts of the body break off and leave the primary tumor at late stages of disease development, scientists from the Wellcome Trust Sanger Institute and their collaborators have found.

14 Aug 2017

Study provides promising framework to anticipate drug resistance in cancer

Being able to predict the resistance or sensitivity of a tumor cell to a drug is a key success-factor of cancer precision therapy.

14 Aug 2017

Researchers create anti-cancer drugs that can effectively kill 58 types of tumors

Boise State University researchers have created anti-cancer drugs that are effective at killing 58 of the 60 types of tumors found in the National Cancer Institutes NCI-60 panel of cancer cells, which affect nine organ systems in the human body.

14 Aug 2017

Counteracting premature aging

Aging is the continuing process of such stress exposures, and with advancing age (normal aging), we must carry lots of senescent cells within our bodies. Senescent cells also often provide some ‘bad influences’ to surrounding healthy cells; such as chronic inflammation and tumorigenesis

14 Aug 2017

Highly sensitive blood test holds potential for quickly tracking cancer growth and spread

Stanford University scientists have described a new type of test that can detect genetic mutations in minute amounts of DNA released from cancer cells into the blood.

14 Aug 2017

Goldfish survive lack of oxygen for months by converting their carbs to alcohol

A new study has shown that goldfish and similar crucian carps can live up to five months in icy lakes with extremely low or no oxygen. Evolution of the fish has enabled them to develop a set of enzymes that can help the fish convert their carbohydrates into alcohol.

13 Aug 2017

Newly discovered immunodeficiency can make people seriously ill from chickenpox virus

A mutation in one of the sensors that the immune system uses to detect viruses can, in rare cases, turn infections with the chickenpox virus into a life-threatening matter.

11 Aug 2017

Duke researchers map evolution of sex chromosomes in fungus linked to human disease

Biologically speaking, nearly every species on Earth has two opposite sexes, male and female. But with some fungi and other microbes, sex can be a lot more complicated.

11 Aug 2017

Better analysis of kidney tumor samples

Every year, just over 1000 people are diagnosed with kidney cancer in Sweden. The three most common variants are clear cell, papillary and chromophobe renal cancer.

11 Aug 2017

Experts highlight need to respect women's autonomy in prenatal testing

Noninvasive fetal genetic sequencing done early in pregnancy is poised to become a routine part of prenatal care.

11 Aug 2017

Feinstein researcher awarded NIH grant to better understand genetic causes of Alzheimer's disease

Feinstein Institute for Medical Research Assistant Professor Yun Freudenberg-Hua, MD, has been awarded a five-year, $600,000 grant from the National Institutes of Health's National Institute on Aging to identify genetic risk factors for Alzheimer's disease.

11 Aug 2017

Researchers develop new technique to locate pathogenic mutations in dark, non-coding genome

When doctors can't find a diagnosis for patient's disease, they turn to genetic detectives. Equipped with genomic sequencing technologies available for less than 10 years, these sleuths now routinely search through a patient's DNA looking for mutations responsible for mysterious diseases.

11 Aug 2017

Study shows that gene outside the brain controls ability to rebound from sleep deprivation

UCLA scientists report the first evidence that a gene outside the brain controls the ability to rebound from sleep deprivation -- a surprising discovery that could eventually lead to greatly improved treatments for insomnia and other sleep disorders that do not involve getting a drug into the brain.

11 Aug 2017

New version of gene editing technique corrects molecular mistakes in RNA-based diseases

Until recently, the CRISPR-Cas9 gene editing technique could only be used to manipulate DNA. In a 2016 study, University of California San Diego School of Medicine researchers repurposed the technique to track RNA in live cells in a method called RNA-targeting Cas9 (RCas9).

11 Aug 2017

Genome News and Research

Impaired DNA replication may lead to trans-generational inheritance of epigenetic changes

Research shows how glutamine plays role in regulating cellular differentiation programs

Liquid biopsies show potential use for cancer screening

Study offers novel insights into how genetic variants play key role in human immune system

Lab-grown miniature blood vessels mimic rare Hutchinson-Gilford Progeria Syndrome

Researchers develop and validate new assay that detects gene fusions in solid tumors

Study shows how breast cancer cells spread late in disease development

Study provides promising framework to anticipate drug resistance in cancer

Researchers create anti-cancer drugs that can effectively kill 58 types of tumors

Counteracting premature aging

Highly sensitive blood test holds potential for quickly tracking cancer growth and spread

Goldfish survive lack of oxygen for months by converting their carbs to alcohol

Newly discovered immunodeficiency can make people seriously ill from chickenpox virus

Duke researchers map evolution of sex chromosomes in fungus linked to human disease

Better analysis of kidney tumor samples

Experts highlight need to respect women's autonomy in prenatal testing

Feinstein researcher awarded NIH grant to better understand genetic causes of Alzheimer's disease

Researchers develop new technique to locate pathogenic mutations in dark, non-coding genome

Study shows that gene outside the brain controls ability to rebound from sleep deprivation

New version of gene editing technique corrects molecular mistakes in RNA-based diseases

Genetics & Genomics - Second Edition eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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