Genome News and Research

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New ‘5-D fingerprint’ technique could precisely measure properties of individual protein molecules

In research that could one day lead to advances against neurodegenerative diseases like Alzheimer's and Parkinson's, University of Michigan engineering researchers have demonstrated a technique for precisely measuring the properties of individual protein molecules floating in a liquid.

18 Jan 2017

Enzyme identified in baker's yeast can efficiently annihilate leukemia cells

An enzyme identified in Saccharomyces cerevisiae, commonly known as brewer's or baker's yeast, has passed in vitro trials, demonstrating its capacity to kill acute lymphoblastic leukemia (ALL) cells.

18 Jan 2017

Study finds link between obesity-related disease and epigenetic modifications

Obesity has been linked to "letter" changes at many different sites in the genome, yet these differences do not fully explain the variation in people's body mass index (BMI) or why some overweight people develop health complications while others don't.

18 Jan 2017

Metabolomics and NMR

Bruker has been involved in the Phenome Center network since its beginning. Several years ago, the whole visionary concept of a global phenome network was actually born with Professor Jeremy Nicholson and Bruker BioSpin has been part of it since the early stages.

From Bruker BioSpin - NMR, EPR and Imaging 17 Jan 2017

Epigenetic changes drive successful metastases of pancreatic cancer cells

A multicenter team of researchers reports that a full genomic analysis of tumor samples from a small number of people who died of pancreatic cancer suggests that chemical changes to DNA that do not affect the DNA sequence itself yet control how it operates confer survival advantages on subsets of pancreatic cancer cells.

17 Jan 2017

Researchers explore how metastatic pancreatic cancer gets ‘reprogrammed’ for optimal malignancy

Metastatic pancreatic cancer -- cancer that has spread from the pancreas to other tissues and is responsible for most patient deaths -- changes its metabolism and is "reprogrammed" for optimal malignancy, according to new findings reported Jan. 16 in Nature Genetics.

16 Jan 2017

Endogenous retroviruses may have played significant role in development of the brain

Over millions of years retroviruses have been incorporated into our human DNA, where they today make up almost 10 per cent of the total genome.

12 Jan 2017

Equipment for single-cell genomics launched by Illumina and Bio-Rad

Illumina, Inc. and Bio-Rad Laboratories, Inc. today announced the launch of the Illumina® Bio-Rad® Single-Cell Sequencing Solution at the J.P. Morgan Healthcare Conference. The comprehensive solution is the first next-generation sequencing (NGS) workflow for single-cell analysis, providing researchers the ability to investigate the coordinated contribution of individual cells in tissue function, disease progression, and therapeutic response.

From Illumina, Inc. 12 Jan 2017

NovaSeq, the new sequencer by Illumina, said to transform the field of genomics

Illumina, Inc., the global leader in next-generation sequencing technology, today introduced the NovaSeqTM Series, a new and scalable sequencing architecture expected one day to enable a $100 genome. Unveiled at the J.P. Morgan Healthcare Conference, this platform redefines high throughput sequencing with unrivaled throughput, ease of use, low per sample costs, and unmatched flexibility.

From Illumina, Inc. 12 Jan 2017

Epigenetic modification may be cause of adult throat cancers linked to alcohol, tobacco use

A team of researchers at the Research Institute of the McGill University Health Centre has found an epigenetic modification that might be the cause of 15% of adult cancers of the throat linked to alcohol and tobacco use.

12 Jan 2017

Genes implicated in rare pediatric epilepsy contribute to common forms of disorder, study finds

An international study led by Columbia University Medical Center and NewYork-Presbyterian researchers has found that several genes previously implicated only in rare, severe forms of pediatric epilepsy also contribute to common forms of the disorder.

12 Jan 2017

UCM scientists design biosensor capable of detecting cancer autoantibodies at early stages

Before a malignant tumor is developed, the immune system tries to fight against proteins that are altered during their formation, producing certain cancer antibodies.

11 Jan 2017

Illumina and IBM join forces to grow accessibility to genome data interpretation

IBM Watson Health and Illumina, Inc. today announced a groundbreaking partnership to expand access to genome data interpretation by integrating Watson for Genomics into Illumina’s BaseSpace Sequence Hub and tumor sequencing process. The collaboration is designed to help standardize and simplify genomic data interpretation.

From Illumina, Inc. 11 Jan 2017

Roswell Park study provides new insights into gene mutations that can lead to cancer

Predisposition to cancer and cancer progression can result from gene mutations that cause elevated rates of genetic damage.

11 Jan 2017

Researchers identify new subgroup of cervical cancers with different genetic features

A team of University of South Carolina scientists led by Carolyn Banister and Phillip Buckhaults has identified a new subtype of cervical cancer that, like most cervical cancers, is triggered by human papillomavirus (HPV) but whose growth is not directed by the virus, suggesting that therapy targeting these tumors' distinct genomic pathways may improve patient outcomes over standard treatment.

11 Jan 2017

MGH researchers identify gene mutations linked to rare congenital condition involving lack of nose

Researchers from Massachusetts General Hospital led a large, international research team that has identified gene mutations associated with a rare congenital condition involving the absence of a nose and often accompanied by defects involving the eye and reproductive systems.

11 Jan 2017

Genome News and Research

New ‘5-D fingerprint’ technique could precisely measure properties of individual protein molecules

Enzyme identified in baker's yeast can efficiently annihilate leukemia cells

Study finds link between obesity-related disease and epigenetic modifications

Metabolomics and NMR

Epigenetic changes drive successful metastases of pancreatic cancer cells

Researchers explore how metastatic pancreatic cancer gets ‘reprogrammed’ for optimal malignancy

Endogenous retroviruses may have played significant role in development of the brain

Equipment for single-cell genomics launched by Illumina and Bio-Rad

NovaSeq, the new sequencer by Illumina, said to transform the field of genomics

Epigenetic modification may be cause of adult throat cancers linked to alcohol, tobacco use

Genes implicated in rare pediatric epilepsy contribute to common forms of disorder, study finds

UCM scientists design biosensor capable of detecting cancer autoantibodies at early stages

Illumina and IBM join forces to grow accessibility to genome data interpretation

Roswell Park study provides new insights into gene mutations that can lead to cancer

Researchers identify new subgroup of cervical cancers with different genetic features

MGH researchers identify gene mutations linked to rare congenital condition involving lack of nose

Retroviruses almost several hundred million years older than previously thought

Researchers find high-resolution structure of immature Zika virus

Scientists crack genetic code to identify men at risk for prostate cancer that spreads after treatment

Orphan Disease Center establishes new initiative that focuses on ALS

Genetics & Genomics - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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