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TSRI study shows hollowed-out version of CPMV could be effective in human therapies

Viruses aren't always bad. In fact, scientists can harness the capabilities of some viruses for good—modifying the viruses to carry drug molecules, for example.

29 Mar 2016

Researchers use novel technology to sequence Y chromosome in malaria spreading mosquitoes

A team of researchers with the Fralin Life Science Institute at Virginia Tech, working with a large international consortium, has sequenced the Y chromosome--the genetic driver of sex-determination and male fertility-- in a family of malaria spreading mosquitoes.

29 Mar 2016

Promising UCLA discovery could lead to new method for improving cancer treatments

A promising new discovery by UCLA scientists could lead to a new method of identifying cancer patients that express high levels of an enzyme and are more likely to respond to cancer treatments.

29 Mar 2016

UT Southwestern scientists discover mutation that causes X-linked reticulate pigmentary disorder

UT Southwestern Medical Center researchers have discovered a mutation that causes a rare systemic disorder known as X-linked reticulate pigmentary disorder (XLPDR) and, significantly, the unexpected cellular mechanism by which the mutation causes the disease.

29 Mar 2016

SLU scientist describes several tactics that can help cells overcome lesions

In a recent review paper published in Nature Structural & Molecular Biology, SLU scientist Alessandro Vindigni, Ph.D., describes the strategies cells use when their DNA faces replication stress, challenges that may derail a cell's ability to reproduce.

29 Mar 2016

Study identifies genetic differences in kidney tumors of African-Americans

A University of North Carolina Lineberger Comprehensive Cancer Center-led study has identified genetic differences in tumors of African-Americans with the most common type of kidney cancer compared with whites.

26 Mar 2016

Inactivation of protein-coding gene promotes liver tissue regeneration in mammals

Scientists at the Children's Medical Center Research Institute at UT Southwestern (CRI) report that inactivating a certain protein-coding gene promotes liver tissue regeneration in mammals.

26 Mar 2016

Neuroscientists decipher new pathway in stem cell differentiation

How do neurons become neurons? They all begin as stem cells, undifferentiated and with the potential to become any cell in the body.Until now, however, exactly how that happens has been somewhat of a scientific mystery. New research conducted by UC Santa Barbara neuroscientists has deciphered some of the earliest changes that occur before stems cells transform into neurons and other cell types.

25 Mar 2016

DNA sequence features predict genome-wide binding pattern of key protein involved in brain disorders

Researchers from the University of Illinois at Urbana-Champaign and the University of California-Davis are combining in vivo experimentation with computation for highly accurate prediction of the genome-wide binding pattern of a key protein involved in brain disorders.

25 Mar 2016

Scientists unravel genetic basis of autism spectrum disorder

The types of gene mutations that contribute to autism are more diverse than previously thought, report researchers at University of California, San Diego School of Medicine in the March 24 online issue of The American Journal of Human Genetics. The findings, they say, represent a significant advance in efforts to unravel the genetic basis of autism spectrum disorder (ASD).

25 Mar 2016

Study uncovers role of small RNAs in fine-tuning egg development

All multicellular organisms that reproduce sexually rely on eggs to support early life. Researchers at University of California, San Diego School of Medicine and Ludwig Cancer Research used the tiny roundworm C. elegans as a model to better understand how eggs enable embryonic development, using only the materials already present in them.

25 Mar 2016

Researchers discover human equivalent DAMP protein in plants

A protein that signals tissue damage to the human immune system has a counterpart that plays a similar role in plants, report researchers at the Boyce Thompson Institute.

25 Mar 2016

Virus-generated DNA lurking between human genes, show research

Think your DNA is all human? Think again. And a new discovery suggests it's even less human than scientists previously thought.

24 Mar 2016

Researchers elucidate how cells are blind to chromosome cohesion defects

Research led by Raquel Oliveira, group leader at Instituto Gulbenkian de Ciência, has elucidated how cells are almost blind to chromosome cohesion defects.

24 Mar 2016

New worldwide collaboration aims to speed up effective diagnosis of TB

As World TB day (24 March) marks global efforts to eliminate tuberculosis as a public health problem by 2035, Oxford University researchers, in partnership with Public Health England (PHE), will lead a new worldwide collaboration called CRyPTIC to speed up diagnosis of the disease.

23 Mar 2016

Addition of just two DNA bases to LdAQP1 gene helps Black Fever parasite to overcome antimonial drugs

Wellcome Trust Sanger Institute scientists show how the parasite responsible for the neglected tropical disease Black Fever (visceral leishmaniasis) can become resistant to drug treatment. Studying the whole genomes of more than 200 samples of Leishmania donovani revealed that the addition of just two bases of DNA to a gene known as LdAQP1 stops the parasite from absorbing antimonial drugs.

23 Mar 2016

Pediatric researchers find gene variants that can strongly increase bone strength in girls

Pediatric researchers have found that rare genetic changes strongly increase the likelihood that a child will have higher bone density, but only in girls.

23 Mar 2016

Whole genome sequencing of chimpanzee parasite reveals clues about human malaria

Understanding the origins of emerging diseases - as well as more established disease agents -- is critical to gauge future human infection risks and find new treatment and prevention approaches. This holds true for malaria, which kills more than 500,000 people a year. Symptoms, including severe anemia, pregnancy-associated malaria, and cerebral malaria, have been linked to the parasite's ability to cause infected red blood cells to bind to the inner lining of blood vessels.

22 Mar 2016

Shigella dysenteriae pathogen probably originated in Europe, genetic study reveals

The largest genetic study on the bacterium responsible for epidemic dysentery has revealed that the Shigella dysenteriae pathogen, which remains a real scourge in Africa and Asia, probably originated in Europe.

22 Mar 2016

TGen scientists highlight advantages of using RNA-sequencing in precision medicine

Uncovering the genetic makeup of patients using DNA sequencing has in recent years provided physicians and their patients with a greater understanding of how best to diagnose and treat the diseases that plague humanity. This is the essence of precision medicine.

22 Mar 2016

Genome News and Research

TSRI study shows hollowed-out version of CPMV could be effective in human therapies

Researchers use novel technology to sequence Y chromosome in malaria spreading mosquitoes

Promising UCLA discovery could lead to new method for improving cancer treatments

UT Southwestern scientists discover mutation that causes X-linked reticulate pigmentary disorder

SLU scientist describes several tactics that can help cells overcome lesions

Study identifies genetic differences in kidney tumors of African-Americans

Inactivation of protein-coding gene promotes liver tissue regeneration in mammals

Neuroscientists decipher new pathway in stem cell differentiation

DNA sequence features predict genome-wide binding pattern of key protein involved in brain disorders

Scientists unravel genetic basis of autism spectrum disorder

Study uncovers role of small RNAs in fine-tuning egg development

Researchers discover human equivalent DAMP protein in plants

Virus-generated DNA lurking between human genes, show research

Researchers elucidate how cells are blind to chromosome cohesion defects

New worldwide collaboration aims to speed up effective diagnosis of TB

Addition of just two DNA bases to LdAQP1 gene helps Black Fever parasite to overcome antimonial drugs

Pediatric researchers find gene variants that can strongly increase bone strength in girls

Whole genome sequencing of chimpanzee parasite reveals clues about human malaria

Shigella dysenteriae pathogen probably originated in Europe, genetic study reveals

TGen scientists highlight advantages of using RNA-sequencing in precision medicine

Genetics & Genomics - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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