Genome News and Research

RSS

Researchers design online database to help researchers identify cancer gene mutations

Many clinical trials use genome sequencing to learn which gene mutations are present in a patient's tumor cells. The question is important because targeting the right mutations with the right drugs can stop cancer in its tracks. But it can be difficult to determine whether there is evidence in the medical literature that particular mutations might drive cancer growth and could be targeted by therapy, and which mutations are of no consequence.

27 Aug 2015

Scientists reveal how a common gene mutation in ALS and FTD disrupts normal cell function

Researchers have determined how the most common gene mutation in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) disrupts normal cell function, providing insight likely to advance efforts to develop targeted therapies for these brain diseases.

27 Aug 2015

GOSH to improve rare disease diagnosis with adoption of Congenica’s Sapientia technology

Ian was ‘a clumsy child’. He kept bumping into objects and couldn’t see well in the dark. He endured 15 years of tests and misdiagnoses during a lengthy, and sometimes traumatic, diagnostic odyssey.

26 Aug 2015

Study of genetic risk factors of IBD in African-Americans published in Gastroenterology journal

Researchers at the Johns Hopkins University School of Medicine, along with colleagues at Emory University and Cedars-Sinai, have published in the journal Gastroenterology the first major, in-depth analysis of genetic risk factors of inflammatory bowel disease in African-Americans.

26 Aug 2015

Persistent leukemia-associated genetic mutations linked to increased risk of relapse, reduced overall survival

In preliminary research, the detection of persistent leukemia-associated genetic mutations in at least 5 percent of bone marrow cells in day 30 remission samples among adult patients with acute myeloid leukemia was associated with an increased risk of relapse and reduced overall survival, according to a study in the August 25 issue of JAMA.

26 Aug 2015

Lingering cancer-related mutations linked to increased risk of relapse, poor survival in leukemia patients

For patients with an often-deadly form of leukemia, new research suggests that lingering cancer-related mutations - detected after initial treatment with chemotherapy - are associated with an increased risk of relapse and poor survival.

26 Aug 2015

BD Life Sciences completes acquisition of Cellular Research

BD Life Sciences, a segment of leading global medical technology company BD (Becton, Dickinson and Company), today announced it has completed the acquisition of Cellular Research, Inc.

From BD (Becton, Dickinson and Company) 26 Aug 2015

Researchers find that humans carry more antibiotic-resistant staphylococci than farm animals

Antibiotic-resistant bacteria are a concern for the health and well-being of both humans and farm animals. One of the most common and costly diseases faced by the dairy industry is bovine mastitis, a potentially fatal bacterial inflammation of the mammary gland (IMI). Widespread use of antibiotics to treat the disease is often blamed for generating antibiotic-resistant bacteria.

25 Aug 2015

Veritas Genetics obtains CE mark approval for myBRCA genetic screening test

Boston-based Veritas Genetics, a pioneer in accessible genetic screening for disease prevention and early detection, received its first European CE mark approval for the company's hereditary breast and ovarian cancer genetic screening test, myBRCA. Veritas introduced myBRCA, which sequences BRCA1 and BRCA2 genes using proprietary gene-targeting technology and Next Generation Sequencing, in North America in May 2015.

25 Aug 2015

Understanding the causes of sudden death in epilepsy: an interview with Professor Sanjay Sisodiya

SUDEP is the sudden unexpected witnessed or unwitnessed, non-traumatic and non-drowning death in people with epilepsy, with or without evidence of a seizure. It doesn’t necessarily have to be in the known context of a seizure, excluding documented status epilepticus, where people have seizure after seizure.

24 Aug 2015

Variation in genetic mechanism increases fat storage and drives obesity

A specific gene region has long been suspected of contributing to obesity in humans but the precise mechanisms behind this were previously unclear. Now, researchers at the Technical University of Munich (TUM), Massachusetts Institute of Technology (MIT), Harvard Medical School and other partners have been able to show that a single genetic alteration in this region reduces thermogenesis (fat burning), instead increasing lipid storage.

24 Aug 2015

Johns Hopkins study advances scientific understanding of how DNA segments move among bacteria

Scientists at Johns Hopkins report they have deciphered the structure and unusual shape of a bacterial protein that prepares segments of DNA for the insertion of so-called jumping genes.

21 Aug 2015

Analysis of toilet waste from international aircraft may lead to global surveillance of infectious diseases

Current international disease surveillance systems are mainly based on reports made by doctors after treatment of infected patients. As a consequence, disease-causing microorganisms and resistance bacteria have time to spread and make large population groups sick before they are detected.

20 Aug 2015

New genome-wide association study sheds light on the underlying biology of polycystic ovary syndrome

Polycystic ovary syndrome (PCOS) has been passed down in many families for generations -- causing reproductive and metabolic health problems for millions of women around the world. Yet, its cause remains unknown despite more than 80 years of research since the disorder was first described in 1935.

20 Aug 2015

Blavatnik Biomedical Accelerator funds advanced biomedical research projects

A few years ago, Andrew Myers' laboratory discovered a new way to synthesize an important class of antibiotics that could one day tackle the toughest, most resistant infections.

20 Aug 2015

Researchers uncover genetic circuit involved in obesity

Like many other conditions, obesity is caused by an interplay between genetic and environmental factors. While efforts to combat the obesity epidemic will need to include changes in diet and exercise, insights into the genes involved may also help with prevention and treatment.

20 Aug 2015

New initiative aims to collect samples from schizophrenia patients across the globe

Institute for Molecular Medicine Finland (FIMM) at the University of Helsinki and The Stanley Center for Psychiatric Research at Broad Institute, together with its international partners, are initiating major new sample collections in several regions and countries.

19 Aug 2015

Further understanding of genetic influence in ALS to be explored in new partnership

Biogen, the ALS Association and Columbia University Medical Center (CUMC) today announced a new collaboration to better understand the differences and commonalities in the ALS disease process and how genes influence the clinical features of the disease.

19 Aug 2015

LINE-1 jumping gene unusually active in gastrointestinal cancer

Results of a trio of studies done on human cancer tissue biopsies have added to growing evidence that a so-called jumping gene called LINE-1 is active during the development of many gastrointestinal cancers.

19 Aug 2015

IDT webinar explores effective RNAi and antisense oligo methods

Integrated DNA Technologies (IDT) will host an informative webinar, entitled ‘Knockdown of lncRNAs: exploring RNAi and antisense oligo methods’, on Tuesday, August 25, 2015. Kim Lennox, a research scientist at IDT and expert in the suppression of gene expression, will present the webinar at 9 am and 1 pm Central Standard Time.

From Integrated DNA Technologies 19 Aug 2015

Genome News and Research

Researchers design online database to help researchers identify cancer gene mutations

Scientists reveal how a common gene mutation in ALS and FTD disrupts normal cell function

GOSH to improve rare disease diagnosis with adoption of Congenica’s Sapientia technology

Study of genetic risk factors of IBD in African-Americans published in Gastroenterology journal

Persistent leukemia-associated genetic mutations linked to increased risk of relapse, reduced overall survival

Lingering cancer-related mutations linked to increased risk of relapse, poor survival in leukemia patients

BD Life Sciences completes acquisition of Cellular Research

Researchers find that humans carry more antibiotic-resistant staphylococci than farm animals

Veritas Genetics obtains CE mark approval for myBRCA genetic screening test

Understanding the causes of sudden death in epilepsy: an interview with Professor Sanjay Sisodiya

Variation in genetic mechanism increases fat storage and drives obesity

Johns Hopkins study advances scientific understanding of how DNA segments move among bacteria

Analysis of toilet waste from international aircraft may lead to global surveillance of infectious diseases

New genome-wide association study sheds light on the underlying biology of polycystic ovary syndrome

Blavatnik Biomedical Accelerator funds advanced biomedical research projects

Researchers uncover genetic circuit involved in obesity

New initiative aims to collect samples from schizophrenia patients across the globe

Further understanding of genetic influence in ALS to be explored in new partnership

LINE-1 jumping gene unusually active in gastrointestinal cancer

IDT webinar explores effective RNAi and antisense oligo methods

Genetics & Genomics - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest News