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ERK and JNK enzymes may offer solutions for treating endometrial, colon cancers

In the quest to solve cancer's mysteries, they come in handy when describing tongue-twisting processes and pathways that somehow allow tumors to form and thrive. Two examples are ERK (extracellular-signal-related kinase) and JNK (c-June N-Terminal Kinase), enzymes that may offer unexpected solutions for treating some endometrial and colon cancers.

3 Oct 2014

Researchers identify biomarker that can predict GS7 prostate cancer patients

Researchers at The University of Texas MD Anderson Cancer Center have identified a biomarker living next door to the KLK3 gene that can predict which GS7 prostate cancer patients will have a more aggressive form of cancer.

3 Oct 2014

Genetic susceptibility to psychosocial stress can increase risk of cardiovascular disease

A new genetic finding from Duke Medicine suggests that some people who are prone to hostility, anxiety and depression might also be hard-wired to gain weight when exposed to chronic stress, leading to diabetes and heart disease.

1 Oct 2014

Salk researchers receive BRAIN Initiative funding

Joseph Ecker, a Salk professor and Howard Hughes Medical Institute investigator, and Margarita Behrens, Salk staff scientist, have been named recipients in the 2014 round of grants from the National Institutes of Health (NIH) through the BRAIN (Brain Research through Advancing Innovative Neurotechnologies) Initiative for leading-edge work in neuroscience.

1 Oct 2014

Three institutions collaborate to study genetics of bipolar disorder, schizophrenia

Researchers at the University of Michigan School of Public Health and Medical School and collaborators at two other institutions will undertake the largest whole genome sequencing study funded to date, as they seek to better understand bipolar disorder and schizophrenia.

30 Sep 2014

New approach to solve global challenges in food security, emerging diseases and biodiversity loss

Solving global challenges in food security, emerging diseases and biodiversity loss requires evolutionary thinking, argues a new study published online in Science Express that was co-authored by Bruce Tabashnik of the University of Arizona College of Agriculture and Life Sciences.

30 Sep 2014

Researchers create new Cas9 animal model for in vivo genome editing experiments

Researchers from the Broad Institute and Massachusetts Institute of Technology have created a new mouse model to simplify application of the CRISPR-Cas9 system for in vivo genome editing experiments.

29 Sep 2014

BRD4 protein appears to play key role in keeping stem cells in immature "pluripotent" state

A protein implicated in several cancers appears to play a pivotal role in keeping stem cells in an immature "pluripotent" state, according to a new study by NYU Langone Medical Center scientists.

26 Sep 2014

Researchers awarded $16 million NIMH grant to create genetic resource for psychiatric disorders

A multi-institutional team of researchers studying schizophrenia and bipolar disorder has been awarded a $16 million grant from the National Institute of Mental Health to create the most extensive genetic resource to date for these two devastating psychiatric disorders, using data assembled by the University of Southern California.

26 Sep 2014

NIH awards grants to 11 research groups to establish AMP RA/Lupus Network

The National Institutes of Health has awarded grants to 11 research groups across the United States to establish the Accelerating Medicines Partnership in Rheumatoid Arthritis and Lupus (AMP RA/Lupus) Network.

25 Sep 2014

Axio Research announces launch of Statistical Genetics and Genomics services

Axio Research announced today the launch of Statistical Genetics and Genomics services in response to the biopharmaceutical industry's need for advanced statistical support in the analysis and interpretation of complex genomic data for drug discovery and development, drug repositioning, and companion diagnostics development.

24 Sep 2014

Researchers explore gene expression in normal vestibular nerves, vestibular schwannomas

Researchers from the University of Toronto, directed by Drs. Gelareh Zadeh and Boris Krischek, investigated gene expression in normal vestibular nerves and vestibular schwannomas (VSs).

24 Sep 2014

UC Riverside collaborating on NSF-funded project to study ancient lineages of fungi

The University of California, Riverside is one of 11 collaborating institutions that have been funded a total of $2.5 million by the National Science Foundation for a project focused on studying zygomycetes - ancient lineages of fungi that include plant symbionts, animal and human pathogens and decomposers of a wide variety of organic compounds.

24 Sep 2014

DNA sequencing may lead to greater care for patients with ventilator-associated pneumonia

A patient survives life-threatening trauma, is intubated in the intensive care unit (ICU) to support his or her affected vital functions, starts to recover, and then develops pneumonia.

23 Sep 2014

New approach to diagnose tuberculosis

Researchers working in the UK and The Gambia, have developed a new approach to the diagnosis of tuberculosis (TB) that relies on direct sequencing of DNA extracted from sputum (a technique called metagenomics) to detect and characterize the bacteria that cause TB without the need for time-consuming culture of bacteria in the laboratory.

23 Sep 2014

Absence of thyroid hormone during development can cause congenital deafness

Fatigue, weight gain, chills, hair loss, anxiety, excessive perspiration - these symptoms are a few of the signs that the thyroid gland, which regulates the body's heart rate and plays a crucial role in its metabolism, has gone haywire.

23 Sep 2014

MIT engineers find new strategy to combat superbugs

In recent years, new strains of bacteria have emerged that resist even the most powerful antibiotics. Each year, these superbugs, including drug-resistant forms of tuberculosis and staphylococcus, infect more than 2 million people nationwide, and kill at least 23,000. Despite the urgent need for new treatments, scientists have discovered very few new classes of antibiotics in the past decade.

22 Sep 2014

Sequencing the Asian liver fluke genome: an interview with Dr Neil Young

Opisthorchis viverrini is a parasitic flatworm (or liver fluke) endemic throughout Thailand, the Lao People’s Democratic Republic, Vietnam and Cambodia. Humans are infected with this parasite when they eat a fluke encysted in inadequately cooked/preserved freshwater fish.

21 Sep 2014

Longer telomeres increase melanoma risk

A leading Dartmouth researcher, working with The Melanoma Genetics Consortium, GenoMEL, an international research consortium, co-authored a paper published today in the Journal of the National Cancer Institute that proves longer telomeres increase the risk of melanoma.

21 Sep 2014

Studies explore role of STXBP5 gene in development of cardiovascular disease

Two independent groups of researchers led by Sidney (Wally) Whiteheart, PhD, of the University of Kentucky, and Charles Lowenstein, MD, of the University of Rochester, have published important studies exploring the role that a gene called STXBP5 plays in the development of cardiovascular disease.

18 Sep 2014

Genome News and Research

ERK and JNK enzymes may offer solutions for treating endometrial, colon cancers

Researchers identify biomarker that can predict GS7 prostate cancer patients

Genetic susceptibility to psychosocial stress can increase risk of cardiovascular disease

Salk researchers receive BRAIN Initiative funding

Three institutions collaborate to study genetics of bipolar disorder, schizophrenia

New approach to solve global challenges in food security, emerging diseases and biodiversity loss

Researchers create new Cas9 animal model for in vivo genome editing experiments

BRD4 protein appears to play key role in keeping stem cells in immature "pluripotent" state

Researchers awarded $16 million NIMH grant to create genetic resource for psychiatric disorders

NIH awards grants to 11 research groups to establish AMP RA/Lupus Network

Axio Research announces launch of Statistical Genetics and Genomics services

Researchers explore gene expression in normal vestibular nerves, vestibular schwannomas

UC Riverside collaborating on NSF-funded project to study ancient lineages of fungi

DNA sequencing may lead to greater care for patients with ventilator-associated pneumonia

New approach to diagnose tuberculosis

Absence of thyroid hormone during development can cause congenital deafness

MIT engineers find new strategy to combat superbugs

Sequencing the Asian liver fluke genome: an interview with Dr Neil Young

Longer telomeres increase melanoma risk

Studies explore role of STXBP5 gene in development of cardiovascular disease

Genetics & Genomics - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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