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Scientists discover network for molecular communication in human embryonic stem cells

Scientists at A*STAR's Genome Institute of Singapore (GIS) and the Max Planck Institute for Molecular Genetics (MPIMG) in Berlin (Germany) have discovered a molecular network in human embryonic stem cells (hESCs) that integrates cell communication signals to keep the cell in its stem cell state.

3 Jul 2013

Genetic variations can identify women who are likely to benefit from breast cancer prevention drug

Scientists found genetic variations that could be used to identify women who are most likely to benefit from a certain type of breast cancer prevention drug—and who should avoid it.

3 Jul 2013

UH and Case Western Reserve University to develop diagnostic tests to determine HIV drug resistance

Case Western Reserve University has signed an exclusive worldwide licensing agreement granting University Hospitals Case Medical Center rights to a series of diagnostic tests to determine drug resistance and co-receptor tropism in human immunodeficiency virus.

2 Jul 2013

Study offers new insights into how genome gets regulated by signalling molecules within human cells

There's not much difference between what makes a man and what makes his beer - at least at the molecular level - according to a new study led by Professor John Schwabe at the University of Leicester.

2 Jul 2013

UCSF researchers find that vitamin C may help stem cells, in vitro fertilization

Vitamin C affects whether genes are switched on or off inside mouse stem cells, and may thereby play a previously unknown and fundamental role in helping to guide normal development in mice, humans and other animals, a scientific team led by UC San Francisco researchers has discovered.

2 Jul 2013

Study reveals strain of V. cholerae in Haiti cholera outbreak originated from single source

The strain of cholera that has sickened thousands in Haiti came from a single source and was not repeatedly introduced to the island over the past three years as some have thought, according to a new study published in mBio-, the online open-access journal of the American Society for Microbiology.

2 Jul 2013

RORA: A novel candidate gene for autism regulates large number of other genes

A new study by Valerie Hu, Ph.D., professor of biochemistry and molecular medicine at the George Washington University (GW) School of Medicine and Health Sciences (SMHS), reports that RORA, a novel candidate gene for autism discovered by her group in a 2010 study, regulates a large number of other genes associated with autism.

2 Jul 2013

Case Comprehensive Cancer Center secures "outstanding" rating from NCI

The Case Comprehensive Cancer Center (CCCC) again demonstrated the compelling power of partnership in securing an overall rating of "outstanding" and a five-year renewal of its grant from the National Cancer Institute (NCI).

28 Jun 2013

Researchers receive NIH grant to study 3-D structure of Plasmodium's genome during parasite's erythrocytic cycle

Malaria is one of the most important infectious diseases in the developing world, with the absence of a vaccine and the development of parasite resistance to commonly used antimalarial drugs complicating efforts to fight the deadly disease.

28 Jun 2013

Stanford researchers take new step in deciphering of histone code

A chemical code scrawled on histones - the protein husks that coat DNA in every animal or plant cell - determines which genes in that cell are turned on and which are turned off.

28 Jun 2013

UNIGE researchers identify genomic variations associated with trisomy 21

Down syndrome, more commonly known as "trisomy 21" is very often accompanied by pathologies found in the general population: Alzheimer's disease, leukemia, or cardiac deficiency.

28 Jun 2013

Scientists compare DNA sequences, genes of domestic and wild tomatoes

You say tomato, I say comparative transcriptomics. Researchers in the U.S., Europe and Japan have produced the first comparison of both the DNA sequences and which genes are active, or being transcribed, between the domestic tomato and its wild cousins.

27 Jun 2013

Second Edition of Human Evolutionary Genetics now available

Garland Science is proud to announce the publication of the long-awaited Second Edition of Human Evolutionary Genetics by Jobling, Hollux, Hurles, Kivisild, and Tyler-Smith.

27 Jun 2013

Planktonic bacteria streamline their genetic makeup to become lean, mean survival machines

Planktonic bacteria inhabiting the world's oceans have streamlined their genetic makeup to become lean, mean survival machines, according to new research by an international team of researchers, including microbiologists at the University of British Columbia.

25 Jun 2013

HHS inspector general details prescription-writing abuses

The new report finds that health providers such as massage therapists, chiropractors and athletic trainers often wrote prescriptions -- and Medicare paid for them.

25 Jun 2013

Investigators uncover connection between tumor metabolic process and progression of kidney cancer

Investigators in The Cancer Genome Atlas (TCGA) Research Network have uncovered a connection between how tumor cells use energy from metabolic processes and the aggressiveness of the most common form of kidney cancer, clear cell renal cell carcinoma (ccRCC).

24 Jun 2013

Researchers identify biological roots of migraine from large-scale genome study

In the largest study of migraines, researchers have found 5 genetic regions that for the first time have been linked to the onset of migraine. This study opens new doors to understanding the cause and biological triggers that underlie migraine attacks.

24 Jun 2013

Bacterial DNA more likely to integrate in the genome of tumors than in normal healthy cells

Bacterial DNA may integrate into the human genome more readily in tumors than in normal human tissue, according to a new study from the University of Maryland School of Medicine's Institute for Genome Sciences. Researchers analyzed genomic sequencing data available from the Human Genome Project, the 1,000 Genomes Project and The Cancer Genome Atlas (TCGA). They considered the phenomenon of lateral gene transfer (LGT), the transmission of genetic material between organisms in the absence of sex.

21 Jun 2013

MPIIB researchers show that Chlamydia infections can cause mutations in host DNA

Chlamydia trachomatis is a human pathogen that is the leading cause of bacterial sexually transmitted disease worldwide with more than 90 million new cases of genital infections occurring each year. About 70 percent of women infected with Chlamydia remain asymptomatic and these bacteria can establish chronic infections for months, or even years. Even when it causes no symptoms, Chlamydia can damage a woman's reproductive organs. In addition, standard antibacterial drugs are proving increasingly ineffective in complete eradication, as Chlamydia goes in to persistent mode, leading to asymptomatic chronic infection.

21 Jun 2013

Scientists use stem-cell technology to create research cell line from PDAC patient

Pancreatic cancer carries a dismal prognosis. According to the National Cancer Institute, the overall five-year relative survival for 2003-2009 was 6 percent.

21 Jun 2013

Genome News and Research

Scientists discover network for molecular communication in human embryonic stem cells

Genetic variations can identify women who are likely to benefit from breast cancer prevention drug

UH and Case Western Reserve University to develop diagnostic tests to determine HIV drug resistance

Study offers new insights into how genome gets regulated by signalling molecules within human cells

UCSF researchers find that vitamin C may help stem cells, in vitro fertilization

Study reveals strain of V. cholerae in Haiti cholera outbreak originated from single source

RORA: A novel candidate gene for autism regulates large number of other genes

Case Comprehensive Cancer Center secures "outstanding" rating from NCI

Researchers receive NIH grant to study 3-D structure of Plasmodium's genome during parasite's erythrocytic cycle

Stanford researchers take new step in deciphering of histone code

UNIGE researchers identify genomic variations associated with trisomy 21

Scientists compare DNA sequences, genes of domestic and wild tomatoes

Second Edition of Human Evolutionary Genetics now available

Planktonic bacteria streamline their genetic makeup to become lean, mean survival machines

HHS inspector general details prescription-writing abuses

Investigators uncover connection between tumor metabolic process and progression of kidney cancer

Researchers identify biological roots of migraine from large-scale genome study

Bacterial DNA more likely to integrate in the genome of tumors than in normal healthy cells

MPIIB researchers show that Chlamydia infections can cause mutations in host DNA

Scientists use stem-cell technology to create research cell line from PDAC patient

Genetics & Genomics - Second Edition eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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