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$2M federal grant to double computing power at Southwest Foundation For Biomedical Research

The "computer ranch" at the Southwest Foundation for Biomedical Research (SFBR), one of the world's largest clusters of computers for human gene research, will more than double in size this summer, thanks to a $2 million federal grant that will speed the pace of discovery at the Foundation's AT&T Genomics Computing Center.

5 Jun 2010

Researchers one step closer to understand how activity outside of nucleus determines cell's behavior

With the rapid and continuous advances in biotechnology, scientists are better able to see inside the nucleus of a cell to unlock the secrets of its genetic material. However, what happens outside of the nucleus has, in many ways, remained a mystery. Now, researchers with the National Institutes of Health are closer to understanding how activity outside of the nucleus determines a cell's behavior.

5 Jun 2010

Roche's new dual-PCR target HIV-1 viral load test receives FDA approval

Roche Molecular Diagnostics announced today that the Food and Drug Administration (FDA) approved its new dual-PCR target HIV-1 viral load test to quantify the amount of virus in a patient's blood. The COBAS® AmpliPrep/COBAS® TaqMan® HIV-1 Test, v2.0 is the first quantitative viral load test to amplify and detect two separate regions of a target genome and offers a fully automated and reliable solution for physicians to make informed treatment decisions for HIV-1 patients undergoing antiretroviral therapy.

4 Jun 2010

Researchers develop biosensors to monitor concentration of c-di-GMP within single living bacteria cells

Some species of bacteria perform an amazing reproductive feat. When the single-celled organism splits in two, the daughter cell - the swarmer - inherits a propeller to swim freely. The mother cell builds a stalk to cling to surfaces.

4 Jun 2010

Life Technologies partners to create Genomic Cancer Care Alliance

Life Technologies Corporation today announced the creation of the Genomic Cancer Care Alliance to help people battling cancer gain access to treatment options found through analysis of their genomic information. Founding partners include Fox Chase Cancer Center, Scripps Genomic Medicine, and the Translational Genomics Research Institute (TGen). The announcement came during the Consumer Genetics Conference being held June 2-4 in Boston.

4 Jun 2010

Researchers generate the first comprehensive genetic parts list of mouse hypothalamus

A Johns Hopkins and Japanese research team has generated the first comprehensive genetic "parts" list of a mouse hypothalamus, an enigmatic region of the brain — roughly cherry-sized, in humans — that controls hunger, thirst, fatigue, body temperature, wake-sleep cycles and links the central nervous system to control of hormone levels.

4 Jun 2010

Researchers underscore role of jumping genes in maintaining genetic diversity

Using high-throughput sequencing to map the locations of a common type of jumping gene within a person's entire genome, researchers at the University of Pennsylvania School of Medicine found extensive variation in these locations among the individuals they studied, further underscoring the role of these errant genes in maintaining genetic diversity.

4 Jun 2010

Delicate balance of microbes in vagina can vary between healthy women: New study

The delicate balance of microbes in the vagina can vary greatly between healthy women, according to a new study led by the University of Maryland School of Medicine's Institute for Genome Sciences. Researchers hope further study will lead to personalized reproductive medicine for women, allowing doctors to tailor each woman's treatment and health maintenance strategies to her individual microbial make-up.

4 Jun 2010

Detailed analysis of epigenetics of Wilms tumor reveals similarities to stem cells

A detailed analysis of the epigenetics - factors controlling when and in what tissues genes are expressed - of Wilms tumor reveals striking similarities to stem cells normally found in fetal kidneys. These findings by Massachusetts General Hospital Cancer Center researchers have revealed new cellular pathways that are critical for Wilms tumor development and may also apply to other pediatric cancers.

4 Jun 2010

New pricing of $19,500 set for Illumina's individual genome sequencing service

Illumina, Inc. today announced a new price of $19,500 for its individual genome sequencing service. In addition, the company announced a price of $14,500 per genome for groups of five or more participants using the same physician. Individuals with serious medical conditions for whom whole-genome sequencing could provide potential direct clinical value will be eligible for special pricing of $9,500 per genome.

From Illumina, Inc. 4 Jun 2010

Life Technologies, DKFZ collaborate to create National High-Throughput Sequencing Center

Life Technologies Corporation and the German Cancer Research Center (Deutsches Krebsforschungszentrum or DKFZ) today announced their collaboration to create the National High-Throughput Sequencing Center. This exclusive partnership will create the largest sequencing facility in Germany and the first national sequencing center in Europe dedicated to systems biology.

3 Jun 2010

Researchers discover relationship between DNA methylation and positioning of nucleosomes

A previously unknown pattern in DNA methylation - an event that affects cell function by altering gene expression - has been uncovered for the first time by stem cell researchers at UCLA, a finding that could have implications in preventing some cancers and correcting defects in human stem cell lines.

3 Jun 2010

Life Technologies makes equity investment in SGI

Life Technologies Corporation, a provider of innovative life science solutions, announced today that it has made an equity investment in Synthetic Genomics, Inc., a privately held company founded to commercialize synthetic genomic advances. Terms of the investment were not disclosed.

3 Jun 2010

Constellation Pharmaceuticals raises $22 million in Series B financing round

Constellation Pharmaceuticals, Inc., the leading biopharmaceutical company focused on discovering and developing new drugs targeting epigenetic regulation of the human genome, today announced that it has raised $22 million in a Series B financing round.

2 Jun 2010

Illumina commences shipment of new HumanOmni2.5-Quad DNA Analysis BeadChip microarray

Illumina, Inc. today announced that it has begun shipping its new HumanOmni2.5-Quad DNA Analysis BeadChip (Omni2.5). This microarray contains millions of newly discovered genome-wide common and rare variants from the 1,000 Genomes Project (1kGP), selected to maximize its ability to detect new associations.

From Illumina, Inc. 2 Jun 2010

Ablexis to advance transgenic mouse platform for antibody discovery with $12M Series A financing

Ablexis, LLC, a biotechnology company dedicated to developing an innovative, next-generation platform for antibody drug discovery, announced today that it has completed a $12 million Series A financing. The round was led by Third Rock Ventures and included Pfizer Venture Investments. Proceeds from the financing will be used to continue advancing Ablexis' proprietary AlivaMab Mouse transgenic mouse platform for the discovery of human therapeutic antibodies.

2 Jun 2010

Roche, ATCC partner to research real-time endogenous GPCR function with xCELLigence System

G-coupled protein receptors (GPCRs), also known as 7-transmembrane proteins, constitute the single largest class of therapeutic targets for clinical and investigational drugs. There are ~800 predicted members of this class in the human genome, involved in diverse signaling pathways in a wide array of cells and tissue types. Modulation of GPCR function has proven to have therapeutic benefit in a wide variety of diseases in immunology, neurology, cardiology, and oncology.

2 Jun 2010

Texas A&M uses pGAP and IBM supercomputing technology to boost tuberculosis research

IBM today announced that Texas A&M University used IBM supercomputing technology to carry out potentially life-saving tuberculosis research at a rate more than four times faster than was previously possible.

2 Jun 2010

Alnylam, Mount Sinai scientists discover svRNAs that play a critical role in influenza A virus replication

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today the publication of new research findings in the journal Proceedings of the National Academy of Sciences (PNAS) by Alnylam scientists and collaborators from Mount Sinai School of Medicine. In the new study, Alnylam and Mount Sinai scientists discovered a novel class of virus-produced small non-coding RNAs, called small viral RNAs (svRNAs), which play a critical role in the replication of influenza A virus.

2 Jun 2010

MediSapiens completes $1M seed round investment for personalized cancer medicine software

MediSapiens, world's first software company for personalized cancer medicine in oncology clinics and drug development, completed $ 1 million (EUR 0.8 million) seed round investment from Veraventure, ETFIII advised by Eqvitec Partners, VTT Ventures and Lifeline Ventures.

1 Jun 2010

Genome News and Research

$2M federal grant to double computing power at Southwest Foundation For Biomedical Research

Researchers one step closer to understand how activity outside of nucleus determines cell's behavior

Roche's new dual-PCR target HIV-1 viral load test receives FDA approval

Researchers develop biosensors to monitor concentration of c-di-GMP within single living bacteria cells

Life Technologies partners to create Genomic Cancer Care Alliance

Researchers generate the first comprehensive genetic parts list of mouse hypothalamus

Researchers underscore role of jumping genes in maintaining genetic diversity

Delicate balance of microbes in vagina can vary between healthy women: New study

Detailed analysis of epigenetics of Wilms tumor reveals similarities to stem cells

New pricing of $19,500 set for Illumina's individual genome sequencing service

Life Technologies, DKFZ collaborate to create National High-Throughput Sequencing Center

Researchers discover relationship between DNA methylation and positioning of nucleosomes

Life Technologies makes equity investment in SGI

Constellation Pharmaceuticals raises $22 million in Series B financing round

Illumina commences shipment of new HumanOmni2.5-Quad DNA Analysis BeadChip microarray

Ablexis to advance transgenic mouse platform for antibody discovery with $12M Series A financing

Roche, ATCC partner to research real-time endogenous GPCR function with xCELLigence System

Texas A&M uses pGAP and IBM supercomputing technology to boost tuberculosis research

Alnylam, Mount Sinai scientists discover svRNAs that play a critical role in influenza A virus replication

MediSapiens completes $1M seed round investment for personalized cancer medicine software

Genetics & Genomics - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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