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New breakthroughs in AS genome-wide association study

Work done in part by researchers at The University of Texas Health Science Center at Houston has led to the discovery of two new genes that are implicated in ankylosing spondylitis (AS), an inflammatory and potentially disabling disease. In addition, the international research team pinpointed two areas along stretches of DNA that play an important role in regulating gene activity associated with the arthritic condition.

10 Jan 2010

Selection of therapeutic workshops to be presented at the Twelfth Annual BIO CEO & Investor Conference

“This year’s BIO CEO & Investor Conference will provide a unique forum to showcase therapeutic areas with key catalysts – from new and dynamic therapies to cutting edge investment opportunities,” said Alan Eisenberg, executive vice president of Emerging Companies & Business Development at BIO.

9 Jan 2010

SIRIUS XM Radio to broadcast medical breakthroughs and milestones of the last ten years

SIRIUS XM Radio today announced that it will broadcast The Dean's List: A Decade in Medicine, an in-depth special exploring the medical breakthroughs and milestones of the last ten years hosted by Dr. Andrew Brotman, Vice Dean for Clinical Affairs, NYU Langone Medical Center, on Doctor Radio, SIRIUS XM's 24/7 health and medical channel.

9 Jan 2010

Gene therapy may help correct molecular flaws that cause brain disease

Neuroscientists have forged an unlikely molecular union as part of their fight against diseases of the brain and nervous system.

9 Jan 2010

Impulse Accelerated Technologies' FPGA compiler used to deploy DNA biotechnology genome search algorithm

Impulse Accelerated Technologies today announced that its CoDeveloper C-to-FPGA compiler has been used to develop and deploy a DNA biotechnology genome search algorithm on a new, modular FPGA acceleration platform created by Pico Computing, of Seattle, Washington. The Xilinx FPGA-accelerated bioinformatics algorithm, written in C, performs sequence analysis and pair-match scoring of DNA runs with lengths of 25 base pairs.

9 Jan 2010

Cancer Research UK scientists named on New Year's Honours list

Several of Cancer Research UK's scientists have been named on this year's New Year's Honours list, as has the government's National Cancer Director and a long-term supporter of the charity.

9 Jan 2010

ESF-UB Conference to concentrate on potentially clinically relevant polymorphisms

Pharmacogenetics started in the fifties with the discovery of primaquine-related haemolysis among glucose-6-phosphate deshydrogenase deficient patients. At the end of the century, it progressively evolved into Pharmacogenomics, investigating simultaneously multiple gene targets till covering the whole genome in relation with altered drug response.

8 Jan 2010

CSHL scientists explain how initiation of DNA replication is coordinated and controlled by kinase proteins

Scientists at Cold Spring Harbor Laboratory (CSHL) have discovered how a protein long known to be an essential activator of DNA replication actually triggers this process in cells.

8 Jan 2010

Researchers devise method to pinpoint key genetic variations under positive natural selection that may impact human health

Fossils may provide tantalizing clues to human history but they also lack some vital information, such as revealing which pieces of human DNA have been favored by evolution because they confer beneficial traits - resistance to infection or the ability to digest milk, for example. These signs can only be revealed through genetic studies of modern humans and other related species, though the task has proven difficult.

8 Jan 2010

New genetic findings may lead to better interventional therapies for obsessive compulsive disorders

A collaboration between the University of Massachusetts Medical School, the Cummings School of Veterinary Medicine at Tufts University and the Broad Institute at the Massachusetts Institute of Technology has identified a genetic locus on canine chromosome 7 which coincides with an increased risk of obsessive compulsive disorder (OCD) susceptibility.

7 Jan 2010

Mutations in genome regulation machinery identified in clear cell renal cell carcinoma

In a new study, scientists have searched for mutations in the gene regions of more than 100 kidney cancer samples, the largest number of samples from a single tumour type to be sequenced to date.

7 Jan 2010

Protein complex proves valuable for changing cell fate

The DNA contained within each of our cells is exactly the same, yet different types of cells - skin cells, heart cells, brain cells - perform very different functions. The ultimate fate of these cells is encoded not just in the DNA, but in a specific pattern of chemical modifications that overlay the DNA structure.

7 Jan 2010

CSHL scientist discovers how bookmarking protein triggers leukemia

Each cell inherits genes from its parent as well as epigenetic information - what amounts to an instruction manual that specifies which genes should be activated or "expressed," when and to what level.

6 Jan 2010

Agilent Technologies, Covaris sign co-marketing agreement to streamline next-generation sequencing experiments

Agilent Technologies, Inc. (NYSE:A) and Covaris Inc. today announced a co-marketing agreement in which Covaris S2 DNA shearing technology will be marketed with the Agilent SureSelect Target Enrichment System to streamline next-generation sequencing experiments.

6 Jan 2010

Genetic rogue elements could help diagnose breast and bowel cancer

Scientists at The University of Nottingham have found that a group of genetic rogue elements, produced by DNA sequences commonly known as 'junk DNA', could help diagnose breast and bowel cancer.

5 Jan 2010

Carbon nanotube: A viable alternative for rapid DNA sequencing

Faster sequencing of DNA holds enormous potential for biology and medicine, particularly for personalized diagnosis and customized treatment based on each individual's genomic makeup.

4 Jan 2010

Research may point to more effective therapeutic targets for prion diseases

Scientists from The Scripps Research Institute have determined for the first time that prions, bits of infectious protein devoid of DNA or RNA that can cause fatal neurodegenerative disease, are capable of Darwinian evolution.

4 Jan 2010

US-German team studies genome mutations

"While the long term effects of genome mutations are quite well understood, we did not know how often new mutations arise in the first place," said Detlef Weigel, director at the Max Planck Institute in Germany. It is routine today to compare the genomes of related animal or plant species.

3 Jan 2010

Scientists discover a new family of giant virus

After Mimivirus, Mamavirus and the virophage, the group of giant viruses now has a new member called Marseillevirus. Discovered in an amoeba by the team led by Didier Raoult at the Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes research group (CNRS/Université Aix-Marseille 2), a description of this new virus was published this week on the website of the Proceedings of the National Academy of Sciences (PNAS).

31 Dec 2009

Presence of Streptococcus pneumoniae could predict risk of severe disease in H1N1 pandemic influenza

The presence of the Streptococcus pneumoniae in samples that can be easily obtained in clinics and emergency rooms may predict risk of severe disease in H1N1 pandemic influenza.

31 Dec 2009

Genome News and Research

New breakthroughs in AS genome-wide association study

Selection of therapeutic workshops to be presented at the Twelfth Annual BIO CEO & Investor Conference

SIRIUS XM Radio to broadcast medical breakthroughs and milestones of the last ten years

Gene therapy may help correct molecular flaws that cause brain disease

Impulse Accelerated Technologies' FPGA compiler used to deploy DNA biotechnology genome search algorithm

Cancer Research UK scientists named on New Year's Honours list

ESF-UB Conference to concentrate on potentially clinically relevant polymorphisms

CSHL scientists explain how initiation of DNA replication is coordinated and controlled by kinase proteins

Researchers devise method to pinpoint key genetic variations under positive natural selection that may impact human health

New genetic findings may lead to better interventional therapies for obsessive compulsive disorders

Mutations in genome regulation machinery identified in clear cell renal cell carcinoma

Protein complex proves valuable for changing cell fate

CSHL scientist discovers how bookmarking protein triggers leukemia

Agilent Technologies, Covaris sign co-marketing agreement to streamline next-generation sequencing experiments

Genetic rogue elements could help diagnose breast and bowel cancer

Carbon nanotube: A viable alternative for rapid DNA sequencing

Research may point to more effective therapeutic targets for prion diseases

US-German team studies genome mutations

Scientists discover a new family of giant virus

Presence of Streptococcus pneumoniae could predict risk of severe disease in H1N1 pandemic influenza

Genetics & Genomics - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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