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Decoding the genetic links between diabetes, hyperlipidemia, and IBD

Announcing a new publication for Acta Materia Medica journal. Previous epidemiologic studies have shown a close association between type 1 diabetes mellitus (T1DM), hyperlipidemia, and inflammatory bowel disease (IBD), but the causal relationship has not been established.

23 Feb 2024

Study uncovers a biological role of transmembrane protein TMEM208

A recent study conducted in the lab of Dr. Hugo J. Bellen, distinguished service professor at Baylor College of Medicine and principal investigator at the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, has discovered a biological role of a specific transmembrane protein called TMEM208.

23 Feb 2024

Key link discovered between spread of antibiotic resistance genes and drug resistance evolution

Biomedical engineers at Duke University have uncovered a key link between the spread of antibiotic resistance genes and the evolution of resistance to new drugs in certain pathogens.

23 Feb 2024

Persistent COVID-19 could drive virus evolution, new study suggests

Study reveals the prevalence of persistent SARS-CoV-2 infection in the UK, showing its potential role in viral evolution and the emergence of new variants, with implications for long-COVID and public health strategies.

22 Feb 2024

Green tea does not lower the risk of lung cancer

Whether green tea consumption was associated with a lower risk of lung cancer.

22 Feb 2024

Largest genetic study on circulating retinol reveals new insights into its impact on health

Study presents the largest genome-wide association analysis on circulating retinol, identifying genes beyond the primary transport system that influence retinol levels and its broad impacts on health, including potential protective roles against schizophrenia and effects on various clinical phenotypes.

21 Feb 2024

Novel genetic locations associated with primary open-angle glaucoma identified

An international genetic study using multiancestry biobanks has identified novel genetic locations associated with primary open-angle glaucoma (POAG), the most common type of glaucoma and the leading cause of irreversible blindness globally.

20 Feb 2024

Breakthrough gene therapy method utilizes bird retrotransposon for safe gene insertion

The recent approval of a CRISPR-Cas9 therapy for sickle cell disease demonstrates that gene editing tools can do a superb job knocking out genes to cure hereditary disease.

20 Feb 2024

NIH-funded research enhances genetic testing for health equity

To prevent an emerging genomic technology from contributing to health disparities, a scientific team funded by the National Institutes of Health has devised new ways to improve a genetic testing method called a polygenic risk score.

20 Feb 2024

Novel genetic associations with anxiety unveiled in comprehensive study of over 1.2 million people

The genetic basis of anxiety disorders, identify genetic loci, and calculate polygenic risk scores for anxiety.

20 Feb 2024

Selection, optimization, and validation of genetic tests for 10 common diseases

By analyzing millions of small genetic differences across a person's genome, researchers can calculate a polygenic risk score to estimate someone's lifetime odds of developing a certain disease.

19 Feb 2024

Mapping the genomic landscape of Type 2 diabetes

In the largest genome-wide association study to date on Type 2 diabetes, a team of international researchers, co-led by a University of Massachusetts Amherst genetic epidemiologist, has located 1,289 genetic markers associated with Type 2 diabetes (145 of which are newly identified) and generated risk scores for diabetes complications.

19 Feb 2024

Study suggests high levels of vitamin B3 breakdown products are linked to higher risk of mortality, heart attacks, and stroke

Researchers utilized an untargeted metabolomics technique to look for new compounds and pathways that may contribute to residual cardiovascular disease risk.

19 Feb 2024

Husker research duo selected as Phase 1 winners in the NIH's Targeted Genome Editor Delivery Challenge

A Husker research duo was named a first-round winner in a National Institutes of Health competition aimed at generating solutions for delivering genome-editing technology to the cells of people with rare and common diseases.

19 Feb 2024

Identification of genetic determinants of micronucleus formation

The genetic determinants of micronuclei formation (MN).

19 Feb 2024

Research demonstrates a bat species' resistance to cancer, pinpoints key genes

A study reveals Myotis pilosus bats exhibit exceptional cancer resistance through gene downregulation, offering insights into natural anticancer mechanisms.

18 Feb 2024

Exome sequencing unravels complex genetic diagnoses in growth disorders

In an article published in the Journal of Pediatrics, researchers based in Brazil describe the case of a nine-year-old boy admitted to hospital with multiple symptoms and overlapping conditions that made diagnosis difficult, such as short stature, thin tooth enamel (dental enamel hypoplasia), moderate mental deficiency, speech delay, asthma, mildly altered blood sugar, and a history of recurring infections in infancy.

16 Feb 2024

Study uncovers key genes and cell types that may affect pathogenesis of primary open-angle glaucoma

Although primary open-angle glaucoma (POAG) is the leading cause of blindness in people over the age of 55, there remains no cure for the disease and its biological mechanisms are not well understood.

16 Feb 2024

Transforming Cancer Care: Aventa Genomics and the Future of Genomic Testing

In this interview, Chris Roberts of Aventa Genomics highlights the groundbreaking Aventa FusionPlus test, detailing its superior ability to detect gene fusions in cancer diagnostics and its pivotal role in advancing personalized oncology treatments.

From Aventa Genomics 16 Feb 2024

New DNA recombination toolbox surpasses CRISPR for genome engineering

Belgian researchers from VIB-KU Leuven Center for Microbiology and VIB-UGent Center for Plant Systems Biology have developed a new toolbox of 16 different short DNA sequences that allow triggering controlled and specific recombination events in any genome.

16 Feb 2024