Genomic News and Research

RSS

Researchers identify new neuroprotective factor that holds potential to help people with glaucoma

A research team led by scientists at the Krembil Research Institute in Toronto has identified a new neuroprotective factor that has the potential to help people suffering from the common blinding disease glaucoma.

7 Nov 2017

Pioneering research to grow mini bowel cancer tumor models in the lab

Charity Cancer Research UK has awarded the University of Birmingham £1.5 million to fund a five-year research program aimed at finding new treatments for bowel cancer.

6 Nov 2017

Gut bacteria can influence how cancer responds to immunotherapy

Bacteria that live in the human digestive tract can influence how cancer responds to immunotherapy, opening a new avenue for research to improve treatment, a team led by researchers at The University of Texas MD Anderson Cancer Center reports in the journal Science.

2 Nov 2017

Study solves critical piece of deafness puzzle by identifying long non-coding RNAs

A new Tel Aviv University study solves a critical piece of the puzzle of human deafness by identifying the first group of long non-coding RNAs (lncRNAs) in the auditory system.

2 Nov 2017

University of Birmingham researchers receive £1.5 million to find new treatments for bowel cancer

Charity Cancer Research UK has awarded the University of Birmingham £1.5 million to fund a five-year research program aimed at finding new treatments for bowel cancer.

2 Nov 2017

Discovery of genetic markers could guide individualized treatments for advanced prostate cancer

Researchers at Mayo Clinic Center for Individualized Medicine have uncovered genetic clues to why tumors resist a specific therapy used for treating advanced prostate cancer.

2 Nov 2017

Researchers compile biggest recorded collection of families with epilepsy

Researchers from Swansea University Medical School have joined up with five other centers from around the world to compile the biggest recorded collection of families with forms of epilepsy where genetics may play a part in the recurring feature of the condition.

2 Nov 2017

Researchers show how changes along lining of mammary ducts can lead to breast cancer

Breast cancer researchers have mapped early genetic alterations in normal-looking cells at various distances from primary tumors to show how changes along the lining of mammary ducts can lead to disease.

1 Nov 2017

PARP inhibitors may have efficacy in selected TNBC patients outside of germline BRCA mutation

The investigational PARP inhibitor talazoparib caused regression of patient-derived xenografts (PDXs) of triple-negative breast cancers (TNBC) that had BRCA mutations and also those that did not have BRCA mutations but had other alterations in DNA damage-repair pathways.

1 Nov 2017

Non-invasive diagnostic tool developed for early detection of ovarian cancer

Investigators from Brigham and Women's Hospital and Dana-Farber Cancer Institute are leveraging the power of artificial intelligence to develop a new technique to detect ovarian cancer early and accurately.

31 Oct 2017

Our chromosomes also wrinkle with age, research shows

Grey hair, wisdom, and wrinkles on our skin mark us as we age, but it's the more subtle changes beneath the surface that make us old. Now, researchers have discovered that our chromosomes also wrinkle with age, changing how our immune system renews itself.

31 Oct 2017

Sanford Health to evaluate effectiveness of non-opioid medications

Sanford Health is one of three sites in the U.S. to launch a study to determine if non-opioid medications are as effective in managing pain after carpal-tunnel surgery.

30 Oct 2017

Genome-wide molecular tests can guide treatment in recurrent glioblastoma, study shows

Several patients with recurring glioblastoma, a deadly brain cancer, survived for more than a year in a clinical trial believed to be the first to use comprehensive DNA and RNA sequencing of a patient's tumor to inform treatment for these patients in real-time.

27 Oct 2017

‘Precision Medicine’ may not always be so precise when applied to diverse populations, study says

Precision Medicine in oncology, where genetic testing is used to determine the best drugs to treat cancer patients, is not always so precise when applied to some of the world's more diverse populations, according to a study led by the Translational Genomics Research Institute, an affiliate of City of Hope, and the Keck School of Medicine of the University of Southern California.

27 Oct 2017

Dream Team plans to stop pancreatic cancer before symptoms occur

Deeply entrenched and mature by the time it's found, pancreatic cancer is one of the hardest to defeat. A Dream Team assembled by Stand Up to Cancer and led by an investigator at The University of Texas MD Anderson Cancer Center will test new ways to find the disease in its emerging, more vulnerable phase in people who are at high risk for developing it.

26 Oct 2017

Research advance may lead to preservation of hearing in people with Usher syndrome type III

A research advance co-led by Case Western Reserve University School of Medicine's Kumar Alagramam, PhD, may stop the progression of hearing loss and lead to significant preservation of hearing in people with Usher syndrome type III, a form of hereditary hearing loss linked to defects in the sensory "hair" cells in the inner ear. USH3 is caused by a mutation in the clarin-1 gene.

26 Oct 2017

New enzyme may one day enable genome surgery that erases harmful mutations

DNA editing just got a sharp, new pencil. Researchers have built an enzyme that can perform a previously impossible DNA swap, directly changing the DNA base pair from an A•T to a G•C.

26 Oct 2017

Direct application of immune cells accelerates healing of acute, chronic wounds in mice

A Massachusetts General Hospital research team has found a surprising potential solution to a persistent clinical problem - the healing of chronic wounds. In their report published in Wound Repair and Regeneration, the investigators from the MGH Vaccine and Immunotherapy Center describe how application of mature B lymphocytes - the immune cells best known for producing antibodies - greatly accelerated the healing of acute and chronic wounds in both diabetic and nondiabetic mice.

25 Oct 2017

Scientists develop unique CRISPR-based method for more precise, systematic gene tagging

The genome editing tool known as CRISPR/Cas9 has opened many doors for biomedical research by allowing scientists to precisely edit DNA sequences and alter function. The technology offers hope for correcting genetic defects and preventing disease.

24 Oct 2017

New genetic variants contribute to the risk of breast cancer in women, study reveals

A new study reveals seventy-two novel genetic variants that are responsible for breast cancer risk. Published in the journals Nature and Nature Genetics, of these 72 variants, 65 are common variants that predispose patients to breast cancer and a further seven variants predispose particularly to estrogen -receptor negative breast cancer - the subcategory of cases that do not respond to hormonal treatments.

24 Oct 2017

Genomic News and Research

Researchers identify new neuroprotective factor that holds potential to help people with glaucoma

Pioneering research to grow mini bowel cancer tumor models in the lab

Gut bacteria can influence how cancer responds to immunotherapy

Study solves critical piece of deafness puzzle by identifying long non-coding RNAs

University of Birmingham researchers receive £1.5 million to find new treatments for bowel cancer

Discovery of genetic markers could guide individualized treatments for advanced prostate cancer

Researchers compile biggest recorded collection of families with epilepsy

Researchers show how changes along lining of mammary ducts can lead to breast cancer

PARP inhibitors may have efficacy in selected TNBC patients outside of germline BRCA mutation

Non-invasive diagnostic tool developed for early detection of ovarian cancer

Our chromosomes also wrinkle with age, research shows

Sanford Health to evaluate effectiveness of non-opioid medications

Genome-wide molecular tests can guide treatment in recurrent glioblastoma, study shows

‘Precision Medicine’ may not always be so precise when applied to diverse populations, study says

Dream Team plans to stop pancreatic cancer before symptoms occur

Research advance may lead to preservation of hearing in people with Usher syndrome type III

New enzyme may one day enable genome surgery that erases harmful mutations

Direct application of immune cells accelerates healing of acute, chronic wounds in mice

Scientists develop unique CRISPR-based method for more precise, systematic gene tagging

New genetic variants contribute to the risk of breast cancer in women, study reveals

Genetics & Genomics - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest News