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Researchers present novel gene-editing technique to prevent retinal angiogenesis

A research team from the Schepens Eye Research Institute of Massachusetts Eye and Ear has successfully prevented mice from developing angiogenesis of the retina--the sensory tissue at the back of the eye--using gene-editing techniques with CRISPR-Cas9.

25 Jul 2017

NETRF announces new research grants to advance treatments for neuroendocrine tumors

The Neuroendocrine Tumor Research Foundation has announced a new round of scientific and clinical research grants, aimed at advancing the treatment of and the search for cures to neuroendocrine tumors.

21 Jul 2017

Genetic variation linked to greater tuberculosis susceptibility

Researchers have shown that a single nucleotide change in a gene that affects production of hepcidin--a peptide involved in inflammation, immunity, and control of iron levels--is associated with greater susceptibility to extrapulmonary tuberculosis.

21 Jul 2017

New genomic research partnership promises to redefine and transform cancer treatment

Personalized cancer therapies are on the horizon thanks to a new genomic cancer research partnership between the Gene Editing Institute of Christiana Care Health System's Helen F. Graham Cancer Center & Research Institute and the biotechnology company NovellusDx.

21 Jul 2017

Epigenetic dysregulation with age in normal breast tissue may contribute to cancer risk

Several known factors are associated with a higher risk of breast cancer including increasing age, being overweight after menopause, alcohol intake, and family history.

20 Jul 2017

Genetic basis behind friendliness of dogs and humans uncovered in a new study

In a new study published in the journal Science Advances a connection was found between friendliness of dogs and a particular genetic makeup. Dogs differ from their closest cousins – wolves, in their friendliness towards humans and the gene that makes this possible has now been uncovered. This gene that allows for the hypersocial behaviour in dogs is also common in humans the study finds.

19 Jul 2017

New study shows how social interaction impacts treatment response in cancer patients

How well cancer patients fared after chemotherapy was affected by their social interaction with other patients during treatment, according to a new study by researchers at the National Human Genome Research Institute, part of the National Institutes of Health, and the University of Oxford in the United Kingdom.

19 Jul 2017

New antibiotic-releasing polymer may simplify treatment of prosthetic joint infection

A team of Massachusetts General Hospital investigators has developed an antibiotic-releasing polymer that may greatly simplify the treatment of prosthetic joint infection.

18 Jul 2017

Scientists reveal key role of TLK2 gene in placenta development, embryo viability in mice

The placenta, a transient organ that links the developing embryo to its mother, is responsible for nutrient, waste and gas exchange between the fetus and the mother.

17 Jul 2017

MGH researchers identify novel mechanism behind resistance to angiogenesis inhibitors

A Massachusetts General Hospital research team has identified a novel mechanism behind resistance to angiogenesis inhibitors - drugs that fight cancer by suppressing the formation of new blood vessels.

14 Jul 2017

Mayo Clinic and nference launch startup to develop drugs for rare diseases

Today, Mayo Clinic and nference launch a startup company for drug development that will be powered by clinical expertise and artificial intelligence (AI).

14 Jul 2017

Targeting immune cells could lead to new treatments for pulmonary fibrosis

Northwestern Medicine scientists have demonstrated that a unique population of immune cells plays a key role in the development of pulmonary fibrosis, and showed that targeting such cells could lead to new treatments for the disease.

13 Jul 2017

Computational analysis of open-access data points to new ways of using drugs

A research team led by scientists at UC San Francisco has developed a computational method to systematically probe massive amounts of open-access data to discover new ways to use drugs, including some that have already been approved for other uses.

12 Jul 2017

Study shows potential of whole genome sequencing and AI to help clinicians scale precision oncology

In a study published today in the July 11, 2017 issue of Neurology Genetics, an official journal of the American Academy of Neurology, researchers at the New York Genome Center, The Rockefeller University and other NYGC member institutions, and IBM have illustrated the potential of IBM Watson for Genomics to analyze complex genomic data from state-of-the-art DNA sequencing of whole genomes.

11 Jul 2017

JAX researchers explore how dendritic cells promote adaptive immunity to virus

A research team led by Jackson Laboratory Professor Karolina Palucka, M.D., Ph.D., in collaboration with a research team at Institut Curie in France led by Dr. Nicolas Manel, have addressed a long-standing puzzle of immunology: How do dendritic cells (DCs) do their job of promoting adaptive immunity to a virus while avoiding getting infected themselves?

7 Jul 2017

Novel technique analyzes sperm morphology and motility in embryo formation process

The research, presented at the European Society of Human Reproduction and Embryology annual conference, which ends today in Geneva, Switzerland, describes for the first time the use of an experimental technique that has made it possible to analyze the functioning of human sperm in contact with the cytoplasmic content of the eggs in vitro.

7 Jul 2017

Large NIH grant awarded to Dartmouth researchers for cooperative lung cancer project

Significant research funding in the form of a five-year, $12.1 million U19 Grant from the National Institutes of Health has been awarded to a collaboration of research teams co-led by Dartmouth's Christopher Amos, PhD, to study and improve precision of lung cancer risk and screening.

7 Jul 2017

CHOP researchers pinpoint WDR26 haploinsufficiency as cause for rare genetic syndrome

Researchers have identified a rare genetic syndrome characterized by intellectual disability, seizures, an abnormal gait and distinctive facial features.

6 Jul 2017

Study reveals link between higher BMI and increased risk of cardiometabolic diseases

Results of a new study add to the evidence of an association between higher body mass index (BMI) and increased risk of cardiometabolic diseases such as hypertension, coronary heart disease, type 2 diabetes, according to a study published by JAMA Cardiology.

5 Jul 2017

First systematic genomic analysis of patients with T-ALL may aid development of new therapies

A consortium including St. Jude Children's Research Hospital and the Children's Oncology Group has performed an unprecedented genomic sequencing analysis of hundreds of patients with T-lineage acute lymphoblastic leukemia (T-ALL).

4 Jul 2017

Genomic News and Research

Researchers present novel gene-editing technique to prevent retinal angiogenesis

NETRF announces new research grants to advance treatments for neuroendocrine tumors

Genetic variation linked to greater tuberculosis susceptibility

New genomic research partnership promises to redefine and transform cancer treatment

Epigenetic dysregulation with age in normal breast tissue may contribute to cancer risk

Genetic basis behind friendliness of dogs and humans uncovered in a new study

New study shows how social interaction impacts treatment response in cancer patients

New antibiotic-releasing polymer may simplify treatment of prosthetic joint infection

Scientists reveal key role of TLK2 gene in placenta development, embryo viability in mice

MGH researchers identify novel mechanism behind resistance to angiogenesis inhibitors

Mayo Clinic and nference launch startup to develop drugs for rare diseases

Targeting immune cells could lead to new treatments for pulmonary fibrosis

Computational analysis of open-access data points to new ways of using drugs

Study shows potential of whole genome sequencing and AI to help clinicians scale precision oncology

JAX researchers explore how dendritic cells promote adaptive immunity to virus

Novel technique analyzes sperm morphology and motility in embryo formation process

Large NIH grant awarded to Dartmouth researchers for cooperative lung cancer project

CHOP researchers pinpoint WDR26 haploinsufficiency as cause for rare genetic syndrome

Study reveals link between higher BMI and increased risk of cardiometabolic diseases

First systematic genomic analysis of patients with T-ALL may aid development of new therapies

Genetics & Genomics - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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