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SETD8 enzyme protects against cellular senescence, research reveals

An enzyme that blocks cellular senescence and its mechanisms has been discovered by a research team from Kumamoto University, Japan. They found that a reduction of the enzyme SETD8, which regulates cell proliferation and gene function, results in the promotion of cell aging features.

8 Mar 2017

Researchers identify key mutation that promotes melanoma growth by suppressing immune response

University of California, Irvine researchers have identified a specific mutation that allows melanoma tumor cells to remain undetected by the immune system.

7 Mar 2017

Research findings could guide development of potent combination therapies for leukemia

New findings from Rockefeller University researchers could guide the development of potent combination therapies that deliver more effective and durable treatment of leukemia.

7 Mar 2017

New technology provides extracorporeal support and enables recovery of damaged donor lungs

A multidisciplinary team led by Gordana Vunjak-Novakovic, Mikati Foundation Professor of Biomedical Engineering and Medical Sciences at Columbia Engineering, and Matt Bacchetta, associate professor of surgery at Columbia University Medical Center and NewYork-Presbyterian has--for the first time--maintained a fully functional lung outside the body for several days.

6 Mar 2017

Researchers identify 90 genes in fat that could play key roles in cardiometabolic diseases

A sweeping international effort is connecting the dots between genes in our fat cells and our risk for obesity and cardiometabolic diseases such as heart disease and type 2 diabetes.

6 Mar 2017

New software tool enables quick, easy deletion of DNA in living cells

Until recently, genomics was a "read-only" science, but scientists have developed a tool for quick and easy deletion of DNA in living cells.

3 Mar 2017

BUSM researchers participate in five-year program to develop biomarkers for small vessel disease

To better predict, study and diagnose small vessel disease in the brain and its role in vascular contributions to cognitive impairment and dementia (VCID), Boston University School of Medicine has been selected to participate in MarkVCID, a consortium designed to accelerate the development of new and existing biomarkers for small vessel VCID.

2 Mar 2017

Scientists discover how genetic mutation disarms tumor-suppressing BRCA1 proteins in breast cancer

Of the more than 3 million people with breast cancer in the United Stated, about 10 percent carry an inherited mutation in their BRCA1 gene. In health, the gene is responsible for suppressing tumors. In disease, the gene goes terribly awry.

28 Feb 2017

Scientists gain new insight into early brain pathology of schizophrenia using adult skin cells

The skin cells of four adults with schizophrenia have provided an unprecedented "window" into how the disease began while they were still in the womb, according to a recent paper in Schizophrenia Research.

27 Feb 2017

Microplate specifically for seed genomics designed by Porvair Sciences

Porvair Sciences launched their new Seed Genomics microplate at the recent Plant & Animal Genomics 2017 conference in San Diego (USA) and received an enthusiastic response from the assembled scientists.

From Porvair Sciences Limited 27 Feb 2017

Researchers identify genomic biomarker in nasal passage that can accurately detect lung cancer

A new nasal test may allow patients suspected of having lung cancer to undergo a simple swab of their nose to determine if they have the disease.

27 Feb 2017

Researchers identify genetic variants that may contribute to schizophrenia

New research has identified sections of DNA associated with altered regulation of gene expression underlying schizophrenia.

27 Feb 2017

Scientists unravel mechanism of rare, early phenomenon that can affect human development

The genetic material of an organism encodes the instructions that guide its development. These codes are not written in stone; they can change or mutate any time during the life of the organism.

24 Feb 2017

MGH researchers discover regulators of gene expression programs in medulloblastoma

Massachusetts General Hospital researchers have identified a mechanism that controls the expression of genes regulating the growth of the most aggressive form of medulloblastoma, the most common pediatric brain tumor. In their report published online in Cancer Discovery, the team also identifies potential targets for future treatments.

24 Feb 2017

Pitt study sheds light on shared roots of schizophrenia and rheumatoid arthritis

An in-depth computational analysis of genetic variants implicated in both schizophrenia and rheumatoid arthritis by researchers at the University of Pittsburgh points to eight genes that may explain why susceptibility to one of the disorders could place individuals at lower risk for the other, according to the results of a study published today in the journal npj Schizophrenia.

24 Feb 2017

Initial diagnosis of acute kidney injury may be inaccurate for many patients, study suggests

Researchers from Columbia University Medical Center have found that, for many patients, an initial diagnosis of "acute kidney injury" may have been inaccurate.

24 Feb 2017

Cutting-edge research into dolphin’s genome could provide solutions to human problems

In movies and TV shows, dolphins are often portrayed as heroes who save humans through remarkable feats of strength and tenacity. Now dolphins could save the day for humans in real life, too - with the help of emerging technology that can measure thousands of proteins and an improved database full of genetic data.

24 Feb 2017

Research: Biomaterials that mimic bone marrow can alter blood cell development

Researchers at the University of Illinois report they can alter blood cell development through the use of biomaterials designed to mimic characteristics of the bone marrow.

23 Feb 2017

First breath of newborn shapes lifelong immunological milieu of lungs

The lung is an important interface between the body and the outside environment: with each breath, a surface of roughly 100 square meters exchanges oxygen for carbon dioxide. More than 10,000 liters of air pass adult lungs every day and with this come numerous viruses, bacteria and pollutants, which need to be prevented from entering the body.

22 Feb 2017

Melanoma patients' immunotherapy response linked to diversity and makeup of gut bacteria

Melanoma patients' response to a major form of immunotherapy is associated with the diversity and makeup of trillions of potential allies and enemies found in the digestive tract, researchers at The University of Texas MD Anderson Cancer Center report at the ASCO-Society for Immunotherapy in Cancer meeting in Orlando.

22 Feb 2017

Genomic News and Research

SETD8 enzyme protects against cellular senescence, research reveals

Researchers identify key mutation that promotes melanoma growth by suppressing immune response

Research findings could guide development of potent combination therapies for leukemia

New technology provides extracorporeal support and enables recovery of damaged donor lungs

Researchers identify 90 genes in fat that could play key roles in cardiometabolic diseases

New software tool enables quick, easy deletion of DNA in living cells

BUSM researchers participate in five-year program to develop biomarkers for small vessel disease

Scientists discover how genetic mutation disarms tumor-suppressing BRCA1 proteins in breast cancer

Scientists gain new insight into early brain pathology of schizophrenia using adult skin cells

Microplate specifically for seed genomics designed by Porvair Sciences

Researchers identify genomic biomarker in nasal passage that can accurately detect lung cancer

Researchers identify genetic variants that may contribute to schizophrenia

Scientists unravel mechanism of rare, early phenomenon that can affect human development

MGH researchers discover regulators of gene expression programs in medulloblastoma

Pitt study sheds light on shared roots of schizophrenia and rheumatoid arthritis

Initial diagnosis of acute kidney injury may be inaccurate for many patients, study suggests

Cutting-edge research into dolphin’s genome could provide solutions to human problems

Research: Biomaterials that mimic bone marrow can alter blood cell development

First breath of newborn shapes lifelong immunological milieu of lungs

Melanoma patients' immunotherapy response linked to diversity and makeup of gut bacteria

Genetics & Genomics - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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