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Specialized gene editing system paves way to eventual cure for HIV patients

A specialized gene editing system designed by scientists at the Lewis Katz School of Medicine at Temple University is paving the way to an eventual cure for patients infected with HIV, the virus that causes AIDS.

22 Mar 2016

Researchers use DNA sequencing technology to identify gene variants that affect susceptibility to SLE

Demonstrating the potential of precision medicine, an international study based at UT Southwestern Medical Center used next-generation DNA sequencing technology to identify more than 1,000 gene variants that affect susceptibility to systemic lupus erythematosus (SLE).

21 Mar 2016

Advanced genomic sequencing tracks deadly blood infection in cancer patients

The Translational Genomics Research Institute, working with international investigators, have discovered the source of a potential deadly blood infection in more than 50 South American cancer patients.

21 Mar 2016

Computer-assisted methods may help as decision support system to combat Zika virus

Global climate change, international travel, and ineffective vector control programs are aiding the emergence of infectious diseases globally. The currently expanding Zika virus (ZIKV) epidemic is one such problem.

21 Mar 2016

Combined loss of XPO1, BCL11A and REL linked to 2p15p16.1 microdeletion syndrome

Individuals with 2p15p16.1 microdeletion syndrome present with intellectual disability, microcephaly, delayed growth, dysmorphic craniofacial features, and digital abnormalities.

21 Mar 2016

Genomic profiling could help provide targeted therapies for difficult to treat cancer tumors

Research from Rutgers Cancer Institute of New Jersey examining difficult to treat cancer tumors through genomic profiling shows that tumors with alterations in a signaling pathway responsible for cell regulation may respond to targeted therapy regardless of where the tumor originated in the body.

18 Mar 2016

WSU researcher explores new drugs to treat neurological disorders linked to autophagic dysfunction

Repairing the brain's "house-cleaning function," which could help people with Alzheimer's, Parkinson's, amyotrophic lateral sclerosis (ALS) and 100 other diseases, is the focus of recently funded research at Washington State University.

17 Mar 2016

Fujitsu Laboratories develops new technology that accelerates database analyses of genomic information

Fujitsu Laboratories Ltd. announced the development of a technology that accelerates database analyses of the correlations between genomic variations and environmental information, such as disease and lifestyle habits. This technology speeds up the process by a factor of roughly 400 compared to existing methods.

16 Mar 2016

INTEGRA introduces latest version of VIAFILL reagent dispenser

INTEGRA announces the latest version of its VIAFILL reagent dispenser. The VIAFILL is ideal for applications including compound storage / addition, ELISA, genomic / proteomic studies and screening as well as cell based and kinetic assays.

From INTEGRA Biosciences 16 Mar 2016

Genetic study in Sub-Saharan Africa hopes to provide new information about etiology of prostate cancer

Dana-Farber Cancer Institute researchers are leading a multicenter genetic study of prostate cancer in Sub-Saharan Africa to try to find new information about the genetic etiology of prostate cancer

16 Mar 2016

Study on kidney cancer can help pave way toward more effective personalized medicine

Understanding the complexity of cancer is a major goal of the scientific community, and for kidney cancer researchers this goal just got closer. Dr. Chad Creighton, associate professor of medicine and member of the Dan L Duncan Comprehensive Cancer Center Division of Biostatistics at Baylor College of Medicine, led the study that analyzed close to 900 kidney cancers at the molecular level.

15 Mar 2016

Scientists find surprising link between iPS cell reprogramming, blood cell formation and cancer

The ability to reprogram cells has revolutionized stem cell research with major implications for almost all fields of modern biology. A decade ago Shinya Yamanaka described a procedure that revolutionized stem cell biology. Using a genetic trick that introduces a cocktail of four genes into cultured cells from human biopsies, he was able to generate induced pluripotent stem cells (iPS) from mature skin or blood cells

15 Mar 2016

Multi-gene test can help identify early breast cancer patients who can safely be spared chemotherapy

Researchers have shown for the first time that it is possible to use a multi-gene test to identify patients with early breast cancer who can be spared chemotherapy and who will still be alive and well five years after diagnosis.

11 Mar 2016

Russian scientists propose new technique to analyze intestinal metagenomes

A group of Russian scientists, among them staff at the Moscow Institute of Physics and Technology, have proposed a new method for the comparison of metagenome-coupled DNA sequences from all of the organisms in a sample of biological material being investigated.

11 Mar 2016

Negative cancer clinical trials have long-term impact on research

Cancer clinical trials with negative results don't make an immediate splash in the scientific literature, but they do have a long-term impact on cancer research, according to a new study by SWOG, the federally funded international clinical trials network.

11 Mar 2016

Latest and final review of health problems related to Agent Orange exposure during Vietnam War

The latest and final in a series of congressionally mandated biennial reviews of the evidence of health problems that may be linked to exposure to Agent Orange and other herbicides used during the Vietnam War changed the categorization of health outcomes for bladder cancer, hypothyroidism, and spina bifida and clarified the breadth of the previous finding for Parkinson's disease.

11 Mar 2016

New RI-MUHC-led study may change the way we think about prescribing statins

Millions of people today take statins to help lower their cholesterol level. Currently statins are prescribed to patients based on their future risk of cardiovascular disease - mainly driven by age - which excludes many individuals who may benefit from them. A new study led by the Research Institute of the McGill University Health Centre in Montreal, with collaborators from the United-States, is changing the way we think about prescribing statins. The research team has developed a new approach to determine which individuals should receive these important medications.

11 Mar 2016

Scientists identify novel gene variants associated with childhood BMI

An international team of scientists has identified novel gene locations associated with childhood body mass index (BMI)--an important measurement related to childhood obesity. The meta-analysis, covering over 47,000 children, is the largest genetic study to date of childhood BMI.

11 Mar 2016

New, regenerative medicine approach developed to remove congenital cataracts in infants

Researchers at University of California, San Diego School of Medicine and Shiley Eye Institute, with colleagues in China, have developed a new, regenerative medicine approach to remove congenital cataracts in infants, permitting remaining stem cells to regrow functional lenses.

10 Mar 2016

CNIO researchers find panoramic view of proteins that intervene in a cellular process

Three years ago, the research team directed by Óscar Fernández-Capetillo, head of the Genomic Instability Group at the Spanish National Cancer Research Centre, obtained, for the first time, a panoramic view of the proteins that intervene in one of the most important and delicate cellular processes: the copying of genetic material during cellular division. They observed that the parts of the genome where the DNA was copied were also very rich in the modification by some very particular proteins, SUMOylations, and poor in others, ubiquitinations, but they were unable to understand why.

8 Mar 2016

Genomic News and Research

Specialized gene editing system paves way to eventual cure for HIV patients

Researchers use DNA sequencing technology to identify gene variants that affect susceptibility to SLE

Advanced genomic sequencing tracks deadly blood infection in cancer patients

Computer-assisted methods may help as decision support system to combat Zika virus

Combined loss of XPO1, BCL11A and REL linked to 2p15p16.1 microdeletion syndrome

Genomic profiling could help provide targeted therapies for difficult to treat cancer tumors

WSU researcher explores new drugs to treat neurological disorders linked to autophagic dysfunction

Fujitsu Laboratories develops new technology that accelerates database analyses of genomic information

INTEGRA introduces latest version of VIAFILL reagent dispenser

Genetic study in Sub-Saharan Africa hopes to provide new information about etiology of prostate cancer

Study on kidney cancer can help pave way toward more effective personalized medicine

Scientists find surprising link between iPS cell reprogramming, blood cell formation and cancer

Multi-gene test can help identify early breast cancer patients who can safely be spared chemotherapy

Russian scientists propose new technique to analyze intestinal metagenomes

Negative cancer clinical trials have long-term impact on research

Latest and final review of health problems related to Agent Orange exposure during Vietnam War

New RI-MUHC-led study may change the way we think about prescribing statins

Scientists identify novel gene variants associated with childhood BMI

New, regenerative medicine approach developed to remove congenital cataracts in infants

CNIO researchers find panoramic view of proteins that intervene in a cellular process

Genetics & Genomics - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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