Genomic News and Research

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Eurofins Genomics, AmpTec sign co-marketing agreement for IVT-RNAs

Eurofins Genomics, international market leader in genomic services, and AmpTec, internationally recognized provider of RNA technology products, have agreed on non-exclusively co-marketing AmpTec's IVT-RNAs globally.

2 Jul 2014

CHOP study: Children with specific gene variants may require higher doses of pain-control drugs

In the first genome-wide analysis of postsurgical pain in children, pediatric researchers identified variations in genes that affect a child's need for pain-control drugs. The findings suggest that at some point physicians may calibrate pain-medication dosages according to a child's individual genetic makeup.

2 Jul 2014

Mayo Clinic researchers uncover 31 genes key to clear cell renal cell carcinoma

A genomic analysis of clear cell renal cell carcinoma (ccRCC), the most common form of kidney cancer, from 72 patients has uncovered 31 genes that are key to development, growth and spread of the cancer, say researchers from Mayo Clinic in Florida.

2 Jul 2014

UCLA receives $7.2 million grant to develop ways to diagnose rare genetic disorders

The David Geffen School of Medicine at UCLA is one of six institutions nationwide chosen by the National Institutes of Health to join their effort in tackling the most difficult-to-solve medical cases and develop ways to diagnose rare genetic disorders.

1 Jul 2014

Study uncovers new information on genes that may increase risk of cardiac arrhythmias

Two international research studies, both led by investigators affiliated with Massachusetts General Hospital (MGH) and the Broad Institute of MIT and Harvard, have uncovered new information about genes that may increase the risk of serious cardiac arrhythmias.

1 Jul 2014

Light-sensitive molecule enables noninvasive silencing of neurons

Optogenetics, a technology that allows scientists to control brain activity by shining light on neurons, relies on light-sensitive proteins that can suppress or stimulate electrical signals within cells. This technique requires a light source to be implanted in the brain, where it can reach the cells to be controlled.

30 Jun 2014

CNIO researchers identify over 40 genes that predict aggressiveness of melanoma

Researchers from the Spanish National Cancer Research Centre have discovered more than 40 genes that predict the level of aggressiveness of melanoma and that distinguish it from other cancers with a poor prognosis. The discovery, published in Cancer Cell, will help to identify unique aspects of melanoma that could contribute to determine the risk of developing metastasis in patients with this disease.

28 Jun 2014

Researchers identify microorganisms that may trigger diarrheal disease among children

In a finding that may one day help control a major cause of death among children in developing countries, a team of researchers led by faculty from the University of Maryland, College Park and the University of Maryland School of Medicine has identified microorganisms that may trigger diarrheal disease and others that may protect against it.

28 Jun 2014

Jackson Laboratory Cancer Center earns renewal of Cancer Center Support Grant from NCI

The Jackson Laboratory Cancer Center has once again earned the renewal of its Cancer Center Support Grant from the National Cancer Institute (NCI).

26 Jun 2014

Current sequencing protocols overlook DNA crucial to bacterial virulence

Genomic sequencing is supposed to reveal the entire genetic makeup of an organism. For infectious disease specialists, the technology can be used to analyze a disease-causing bacterium to determine how much harm it is capable of causing and whether or not it will be resistant to antibiotics.

26 Jun 2014

Researchers compare genome sequences of malaria vectors to investigate insecticide resistance

Researchers from LSTM have exploited a natural experiment created by insecticidal pressure to determine how the most important malaria vectors - A. gambiae s.s. and A. coluzzii - respond rapidly to environmental change.

26 Jun 2014

Gene in brain promotes kidney cancer, report researchers

A gene known to control brain growth and development is heavily involved in promoting clear cell renal cell carcinoma, the most common form of kidney cancer, researchers from Mayo Clinic in Florida are reporting.

25 Jun 2014

UK scientists unlock untapped genetic information to better understand Intellectual Disability in children

Teams of leading UK scientists have joined forces to unlock an untapped source of genetic information in a bid to better understand and treat children with Intellectual Disability. Experts from Cambridge, Cardiff, and UCL (University College London) will be given unprecedented access to genetic information on intellectual disability from NHS Regional Genetics Centres across the UK as part of a first phase study funded by the Medical Research Council and Medical Research Foundation.

24 Jun 2014

Colon has safety mechanism to restrict formation and growth of adenomas

Colon cancer development starts with the formation of benign tumours called adenomas. It is estimated that between 30% and 50% of people over 50 will develop one of these tumours.

24 Jun 2014

Study paves way to develop novel therapies for nasopharyngeal cancer

A team of scientists from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore, National University Cancer Institute Singapore (NCIS) and National University Hospital Singapore (NUH), discovered a distinct mutational signature and nine significantly mutated genes associated with nasopharyngeal cancer, paving the way to developing novel therapies for this deadly disease.

23 Jun 2014

A new breakthrough for treating nasopharyngeal carcinoma

23 Jun 2014

Definiens closes €15M financing round to expand into digital tissue diagnostics

Definiens AG, which offers a unique approach to tissue diagnostics aimed at helping physicians improve treatment, said that it has closed a round of financing for € 15 million.

23 Jun 2014

Yap1 oncogene drives recurrence and progression of pancreatic cancer

Pancreatic cancer tumors addicted to mutant Kras signaling for their growth and progression have a ready-made substitute to tap if they're ever forced to go cold-turkey on the mutant oncogene, scientists at The University of Texas MD Anderson Cancer Center report in the journal Cell.

20 Jun 2014

Research provides unique insight into lncRNAs that regulate lung development

It's a long way from DNA to RNA to protein, and only about two percent of a person's genome is eventually converted into proteins.

19 Jun 2014

DNA sequencing does not reveal the pathogenicity of bacteria

While more and more genomic information is becoming available at a drastically increasing pace, the knowledge we can gain about how microorganisms interact with their surrounding, infect hosts and alter their molecular programs in accordance to changing environmental conditions remains widely not deducible from genomic data alone, the researchers from University of Southern Denmark claim.

19 Jun 2014