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A high-throughput CAMP assay for the evaluation of the vitamin D-dependent antimicrobial response

A recent developed a novel and high-throughput assay to evaluate cathelicidin antimicrobial peptide.

16 Mar 2023

Scientists discover mechanism used by cancer cells to repair DNA damage induced by radiotherapy

A team of scientists led by Dr. Kei-ichi TAKATA from the Center for Genomic Integrity within the Institute for Basic Science (IBS), has discovered a new type of DNA repair mechanism that cancer cells use to recover from next-generation cancer radiation therapy.

16 Mar 2023

An automated bioinformatics pipeline to monitor HIV data in real-time

Researchers discuss an automated bioinformatics pipeline to prospectively and routinely analyze HIV-1 sequence data

15 Mar 2023

Bat stem cells reveal how bats survive in a virus-filled environment

A recent Cell journal study tested the hypothesis that bats genetically induce the virus for immune evasion and provide fertile ground for replication.

15 Mar 2023

Researchers uncover new clue as to how "whole genome doubling" drives cancer

A single cell contains 2-3 meters of DNA, meaning that the only way to store it is to package it into tight coils.

15 Mar 2023

Embryonic stem cells used to recreate thyroid cancer histotypes

A recent Nature Communications study revealed the recapitulating capacity of human embryonic stem cells (hESCs) to elucidate the cellular hierarchy of the thyroid gland. Furthermore, these cells possessed the capacity to reproduce the oncogenic process using the CRISPR-based genetic editing method.

14 Mar 2023

How does dietary intervention affect aging?

Aging is a process that includes multiple interwoven mechanisms that interact with lifestyle factors. A new review seeks to encapsulate the available information on the effect of diet on aging at the cellular level in humans.

14 Mar 2023

New genetic animal model may inform potential therapeutic options for Down syndrome

National Institutes of Health researchers compared a new genetic animal model of Down syndrome to the standard model and found the updated version to be more similar to the changes seen in humans.

14 Mar 2023

Researchers identify the mSWI/SNF chromatin remodeling complex as a host-directed drug target for SARS-CoV-2 infection

Researchers showed that mammalian SWItch/Sucrose Non-Fermentable (mSWI/SNF) chromatin remodeling complexes represent a potential class of host-directed broad-acting SARS-CoV-2 therapeutic targets.

14 Mar 2023

The development of the pediatric oral resistome and its role in dental caries

Researchers performed a genomic investigation of oral resistome development, i.e., of genes that confer antimicrobial resistance.

14 Mar 2023

Schizophrenia risk conferred by rare damaging genetic variants is conserved across ethnicities

Researchers have identified two previously unknown genes linked to schizophrenia and newly implicated a third gene as carrying risk for both schizophrenia and autism.

13 Mar 2023

High-throughput genetic screening approach to study antibiotic proteins made by bacteriophages

As conventional antibiotics continue to lose effectiveness against evolving pathogens, scientists are keen to employ the bacteria-killing techniques perfected by bacteriophages, the viruses that infect bacteria.

13 Mar 2023

Scientists study how maternal SARS-CoV-2 infection during pregnancy affects child’s brain development

Scientists led by the Lieber Institute for Brain Development are studying how a mother's SARS-CoV-2 infection during pregnancy affects the biology of the placenta and the corresponding trajectory of the child's brain development, including the risk for neurodevelopmental disorders such as schizophrenia and autism.

13 Mar 2023

Study highlights poor clinical utility of germline testing in cancer patients of African ancestry

New research in the March 2023 issue of JNCCN-; Journal of the National Comprehensive Cancer Network highlights how the lack of genomic research for people with African ancestry, particularly those from the Sub-Saharan region, is hampering efforts to reduce disparities for people with cancer.

10 Mar 2023

Novel triple assortments of swine influenza virus detected in pigs by active surveillance analysis in China

Researchers discuss the results of an active surveillance analysis for the swine influenza virus.

10 Mar 2023

New discoveries made regarding autism onset in mouse models

Although autism is a common neurodevelopmental disorder, the multiple factors behind its onset are still not fully understood.

10 Mar 2023

MGI supports a national genomic sequencing project that aims to build the largest genetic database in Brazil

MGI Tech Co. Ltd. (MGI), a company committed to building core tools and technology to lead life science, in partnership with Pensabio - a Brazilian distribution company, brings to Brazil a new technology to support a large national genomic sequencing project with sequencers.

From MGI 10 Mar 2023

PacBio to commence first customer shipments of Revio long-read sequencing systems

PacBio, a leading developer of high-quality, highly accurate sequencing solutions, today announced its first customer shipments of Revio long-read sequencing systems will commence on March 8, 2023.

9 Mar 2023

Individuals with autosomal and X-linked recessive deficiency of IRAK-4 and MyD88 are more susceptible to developing hypoxemic COVID-19 pneumonia

Researchers identified that individuals with a deficiency of myeloid differentiation primary response 88 (MyD88) and interleukin-1 receptor-associated kinase 4 (IRAK-4) due to an autosomal recessive condition were highly susceptible to developing hypoxemic coronavirus disease 2019 (COVID-19) pneumonia when infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

9 Mar 2023

Detection and targeting of splicing deregulation reveal a potential strategy for pAML therapy

Pediatric acute myeloid leukemia or pAML is a childhood blood cancer, one that has proved confounding to clinicians and researchers, with a high relapse rate and relatively few identified genetic mutations (compared to the adult version) that might explain its cause.

8 Mar 2023

Genomic News and Research

A high-throughput CAMP assay for the evaluation of the vitamin D-dependent antimicrobial response

Scientists discover mechanism used by cancer cells to repair DNA damage induced by radiotherapy

An automated bioinformatics pipeline to monitor HIV data in real-time

Bat stem cells reveal how bats survive in a virus-filled environment

Researchers uncover new clue as to how "whole genome doubling" drives cancer

Embryonic stem cells used to recreate thyroid cancer histotypes

How does dietary intervention affect aging?

New genetic animal model may inform potential therapeutic options for Down syndrome

Researchers identify the mSWI/SNF chromatin remodeling complex as a host-directed drug target for SARS-CoV-2 infection

The development of the pediatric oral resistome and its role in dental caries

Schizophrenia risk conferred by rare damaging genetic variants is conserved across ethnicities

High-throughput genetic screening approach to study antibiotic proteins made by bacteriophages

Scientists study how maternal SARS-CoV-2 infection during pregnancy affects child’s brain development

Study highlights poor clinical utility of germline testing in cancer patients of African ancestry

Novel triple assortments of swine influenza virus detected in pigs by active surveillance analysis in China

New discoveries made regarding autism onset in mouse models

MGI supports a national genomic sequencing project that aims to build the largest genetic database in Brazil

PacBio to commence first customer shipments of Revio long-read sequencing systems

Individuals with autosomal and X-linked recessive deficiency of IRAK-4 and MyD88 are more susceptible to developing hypoxemic COVID-19 pneumonia

Detection and targeting of splicing deregulation reveal a potential strategy for pAML therapy

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