Geriatrics News and Research

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Brain receptor discovery opens door to new therapies for addiction and mental health

Researchers at the Icahn School of Medicine at Mount Sinai have uncovered insights into the potential mechanism of action of the antipsychotic medication asenapine, a possible therapeutic target for substance use and neuropsychiatric disorders.

2 Jan 2024

Research illustrates how racism is deeply interrelated with poor health outcomes

A team of health equity researchers from several institutions has leveraged a complex web of data to test a hypothesis: That structural racism is associated with resources and structures at the neighborhood level that are closely associated with poor health.

21 Dec 2023

Unraveling nuanced roles of JAK inhibitors in inflammation

Researchers at the Icahn School of Medicine at Mount Sinai have gained a deeper understanding of the nuanced roles of JAK inhibitors, or modulators, in inflammation across various cell types and tissues.

21 Dec 2023

How fasting makes the brain and gut work together for weight loss

Worldwide, more than one billion people are obese. Obesity is a risk factor for cardiovascular disease, diabetes, and some cancers.

20 Dec 2023

New statistical technique improves disease prediction for people of African descent

A team of scientists from Icahn School of Medicine at Mount Sinai has developed a groundbreaking statistical technique, "BridgePRS," to enhance disease prediction in people of non-European ancestry, particularly those of African descent.

20 Dec 2023

Mount Sinai wins $1.3 million NIH award to expand the New York City Virus Hunters program

The Icahn School of Medicine at Mount Sinai has received more than $1.3 million from the National Institute of General Medical Sciences of the National Institutes of Health (NIH) to expand the New York City Virus Hunters program.

14 Dec 2023

Novel machine learning tool predicts gain- and loss-of-function variants across the genome

In a novel study, researchers from the Icahn School of Medicine at Mount Sinai introduced LoGoFunc, an advanced computational tool that predicts pathogenic gain- and loss-of-function variants across the genome.

14 Dec 2023

Blocking an allergy pathway unleashes antitumor immunity in mouse models of non-small cell lung cancer

Researchers at the Icahn School of Medicine at Mount Sinai have identified an allergy pathway that, when blocked, unleashes antitumor immunity in mouse models of non-small cell lung cancer (NSCLC).

6 Dec 2023

Housing instability heightens Alzheimer's risk in veterans

In a recent study published in Journal of the American Geriatrics Society, Veterans with housing instability were 53% more likely to receive a diagnosis of Alzheimer's disease or a related dementia (ADRD) than those with stable housing.

6 Dec 2023

Weight loss leads to dynamical changes in brain function and gut microbiome

Worldwide, more than one billion people are obese. Obesity is a risk factor for cardiovascular disease, diabetes, and some cancers. But permanently losing weight isn’t easy: complex interactions between body systems such as gut physiology, hormones, and the brain are known to work against it. One method for weight loss is intermittent energy restriction (IER), where days of relative fasting alternate with days of eating normally.

4 Dec 2023

Traumatic memories represented differently in the brain, study finds

A new analysis of the brain activity of people with post-traumatic stress disorder (PTSD) is the first to reveal that traumatic memories are represented in the brain in an entirely different way than sad autobiographical memories.

30 Nov 2023

Dementia patients often receive different treatment after hospital transfer, study finds

It is common for individuals seeking medical care for symptoms of concern to go to the nearest hospital. Physicians there may determine the facility cannot provide the care they believe the patient needs and recommend transfer to another hospital offering a higher level of care or specialized services.

28 Nov 2023

Hormone therapy for transmasculine individuals may be safer than previously thought

A common concern about gender-affirming hormone therapy for transmasculine people is the risk of red blood cell volume changes and erythrocytosis, a high concentration of red blood cells, with the use of prescribed testosterone.

27 Nov 2023

Study shows lasting effects of COVID-19 on nursing home residents

COVID-19 raced through nursing homes many times over the past few years, as the virus spread rapidly among vulnerable older adults living close together.

21 Nov 2023

Study provides the first national estimate of family caregivers' pain and arthritis experiences

Researchers from Weill Cornell Medicine provide the first national estimate of caregivers' pain and arthritis experiences that can limit their ability to perform necessary tasks while caring for older family members.

20 Nov 2023

Bioengineered human heart muscle cells and micro-tissues take flight to space

Mount Sinai's Cardiovascular Research Institute is sending bioengineered human heart muscle cells and micro-tissues into space for the first time on NASA's 29th SpaceX commercial resupply services mission, which launched Thursday, November 9.

14 Nov 2023

New study identifies 4,749 key gene clusters that influence progression of 32 cancer types

Researchers at the Mount Sinai Center for Transformative Disease Modeling have released a groundbreaking study identifying 4,749 key gene clusters, termed "prognostic modules," that significantly influence the progression of 32 different types of cancer.

13 Nov 2023

Mary Kay Ash Foundation and UT Southwestern celebrate five years of successful collaboration in advancing cancer research

The Mary Kay Ash Foundation℠, a decades-long leader and advocate for finding cures for cancers affecting women, and UT Southwestern Medical Center, one of the nation’s premier academic medical centers, in Dallas, Texas, are celebrating five years of collaborative success on the International Postdoctoral Scholars in Cancer Research Fellowship program.

13 Nov 2023

Who will care for older adults? We’ve plenty of know-how but too few specialists

Thirty-five years ago, Jerry Gurwitz was among the first physicians in the United States to be credentialed as a geriatrician — a doctor who specializes in the care of older adults.

10 Nov 2023

Diagnosing early-stage lung cancer with CT screening improves survival rate

Diagnosing early-stage lung cancer with low-dose computed tomography (CT) screening drastically improves its cure rate measured over a 20-year period, according to a large-scale international study by Mount Sinai researchers published in Radiology.

7 Nov 2023