Germline News and Research

RSS

New project develops more efficient treatment approaches for cardiovascular diseases

Within the framework of a European collaborative research project, Oliver Müller, professor at the Faculty of Medicine at Kiel University and Consultant at the Department of Internal Medicine III, University Medical Center Schleswig-Holstein, Campus Kiel, will receive 1.4 million Euros for the project "CardioReGenix: Development of Next-Generation Gene Therapies for Cardiovascular Disease".

21 Dec 2018

FDA takes significant step forward in driving development of novel genetic tests

The U.S. Food and Drug Administration today took a significant step forward in driving the efficient development of novel diagnostic technologies that scan a person's DNA to diagnose genetic diseases and guide medical treatments.

5 Dec 2018

New York State approves NYGC's Whole Genome and Transcriptome Sequencing for oncology

The New York Genome Center has received approval from the New York State Department of Health to offer whole genome and RNA transcriptome sequencing in its Clinical Laboratory Evaluation Program-certified laboratory.

29 Nov 2018

ASHG reaffirms cautious but proactive approach recommended in its 2017 position statement on germline genome editing

Given this morning's reports of infants possibly born in China whose genomes were edited by CRISPR-based technology, the American Society of Human Genetics (ASHG) reaffirms the cautious but proactive approach recommended in its 2017 position statement on human germline genome editing, published in The American Journal of Human Genetics.

26 Nov 2018

Participation project calls for relaxing research ban on germline interventions

Are genetic defects allowed to be repaired by intervening with sperm or egg cells, or even human embryos? Thanks to genetic scissors such as CRISPR/Cas, such interventions in the germline could soon become a medical reality.

19 Nov 2018

Scientists pinpoint TIM-3 protein as next potential target for immunotherapy treatments

Following the 2018 Nobel Prize for Medicine, global attention is now more than ever turned toward the promise of immunotherapy in oncology. An international team’s work has shed new light on a molecule called TIM-3 that might play a key role in the regulation of the immune response.

31 Oct 2018

New discovery may lead to better treatment options for pancreatic cancer patients

Pancreatic cancer is one of the most difficult cancers to treat and is a leading cause of cancer-related deaths. Now, Sidney Kimmel Cancer Center - Jefferson Health and Lankenau Institute for Medical Research scientists find that a gene involved in the immune system called IDO2 plays a significant role in pancreatic ductal adenocarcinoma, the most common type of pancreatic cancer.

23 Oct 2018

LYNPARZA Phase III SOLO-1 results show improved outcome for patients with advanced BRCA-mutated ovarian cancer

AstraZeneca and Merck & Co., Inc., Kenilworth, N.J., today announced detailed results from the Phase III SOLO-1 trial testing LYNPARZA (olaparib) 300 mg tablets twice-daily as a maintenance treatment for patients with newly diagnosed advanced BRCA-mutated ovarian cancer who were in complete or partial response following 1st-line standard platinum-based chemotherapy.

22 Oct 2018

Researchers demonstrate epigenetic memory transmission via sperm

A new study suggests that if the epigenetics of sperm chromosomes are altered by the environment a father experiences, then this could affect offspring’s health.

17 Oct 2018

Immunotherapy effective for individuals with inherited form of skin cancer

Individuals with an inherited form of skin cancer often have a poor prognosis. The type of immunotherapy that was awarded this year's Nobel Prize in Physiology or Medicine is, however, particularly effective in this patient group, research from Karolinska Institutet in Sweden shows. The study is published in the Journal of Medical Genetics.

8 Oct 2018

New project identifies immune checkpoint inhibition as potential treatment for angiosarcomas

Angiosarcoma Project, a patient-partnered genomics study, identified immune checkpoint inhibition as a potential treatment option for patients with angiosarcomas of the head, face, neck, or scalp, according to data presented at the fourth CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference.

1 Oct 2018

Research reveals how critical oocyte quality control process works

Females are born with a finite number of eggs that are steadily depleted throughout their lifetime. This reserve of eggs is selected from a much larger pool of millions of precursor cells, or oocytes, that form during fetal life.

28 Sep 2018

Replacement bisphenols cause reproductive defects in lab mice

Twenty years ago, researchers made the accidental discovery that the now infamous plastics ingredient known as bisphenol A or BPA had inadvertently leached out of plastic cages used to house female mice in the lab, causing a sudden increase in chromosomally abnormal eggs in the animals.

14 Sep 2018

Germline News and Research

New project develops more efficient treatment approaches for cardiovascular diseases

FDA takes significant step forward in driving development of novel genetic tests

New York State approves NYGC's Whole Genome and Transcriptome Sequencing for oncology

ASHG reaffirms cautious but proactive approach recommended in its 2017 position statement on germline genome editing

Participation project calls for relaxing research ban on germline interventions

Scientists pinpoint TIM-3 protein as next potential target for immunotherapy treatments

New discovery may lead to better treatment options for pancreatic cancer patients

LYNPARZA Phase III SOLO-1 results show improved outcome for patients with advanced BRCA-mutated ovarian cancer

Researchers demonstrate epigenetic memory transmission via sperm

Immunotherapy effective for individuals with inherited form of skin cancer

New project identifies immune checkpoint inhibition as potential treatment for angiosarcomas

Research reveals how critical oocyte quality control process works

Replacement bisphenols cause reproductive defects in lab mice

Research into biology behind sperm development could offer hope for solving male infertility

Koala virus could provide clues to accumulated 'junk' DNA in the human genome

New study identifies genes linked to higher risk for triple-negative breast cancer

Answer to decades-old mystery may allow some children to avoid bone marrow transplantation

Small RNA in sperm shown to be essential for embryonic development

Stem cell study brings scientists closer to understanding schistosomiasis

Researchers develop new method to identify genes contributing to heritable cancer risk

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest News