Gliomas News and Research

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Researchers discover cellular origins of pediatric brain tumors

A research team led by Dr. Claudia Kleinman, an investigator at the Lady Davis Institute at the Jewish General Hospital, together with Dr. Nada Jabado, of the Research Institute of the McGill University Health Centre, and Dr. Michael Taylor, of The Hospital for Sick Children, discovered that several types of highly aggressive and, ultimately, fatal pediatric brain tumors originate during brain development.

25 Nov 2019

Scientists investigate the dynamics of molecular changes in gliomas

Until relatively recently, cancer was viewed as a single disease with sub-types based on where in the body it arose.

22 Nov 2019

Researchers identify a promising drug pair to attack deadly childhood brain cancers

Researchers have devised a new plan of attack against a group of deadly childhood brain cancers collectively called diffuse midline gliomas, including diffuse intrinsic pontine glioma, thalamic glioma and spinal cord glioma.

20 Nov 2019

Researchers uncover novel molecular clues for tumor aggression in neurofibromatosis type 1

Researchers at the Johns Hopkins Kimmel Cancer Center report that their study of tumor samples from people with the rare genetic syndrome neurofibromatosis type 1 (NF1) has uncovered novel molecular clues about which tumors are most likely to be aggressive in those with NF1

From Johns Hopkins Medicine 18 Oct 2019

Fluorescent tags help diagnose and monitor brain gliomas more effectively

A new study published online in the journal eBioMedicine on October 15, 2019, describes the use of an orally ingested agent called 5-aminolevulinic acid (5-ALA) to confirm the diagnosis of the aggressive brain tumor called glioma.

16 Oct 2019

Study receives NCI grant to explore better treatment for brain tumors in children

Children with recurrent brain tumors or newly diagnosed, particularly aggressive tumors called diffuse intrinsic pontine gliomas are being enrolled in the first study to examine the efficacy of a drug that inhibits an enzyme these tumors use to protect themselves from the child's natural immune response.

8 Oct 2019

UC experts explore if ketogenic diet could help make treatments for glioblastoma

Investigators at the University of Cincinnati are studying whether or not a modified Atkins-type ketogenic diet could help make treatments for a common, but dangerous, type of brain cancer called glioblastoma more effective.

30 Sep 2019

Children's of Alabama using cold sore virus to fight pediatric brain cancer

Children's of Alabama is home to one of the most exciting studies underway in pediatric cancer: evaluating the use of a cold sore virus to treat children with progressive malignant brain tumors.

26 Sep 2019

Brain tumors hijack healthy neurons in order to grow

Scientists have discovered that brain tumors integrate themselves with the brain’s healthy neuronal network to support their growth.

19 Sep 2019

A factor that predicts prolonged survival in brain tumor uncovered

The discoveries in the cellular and molecular biology of cancer, the development of drugs against specific genetic mutations, and the emergence of immunotherapy are allowing the cure or improvement of the quality of life and life expectancy of patients with tumors.

3 Sep 2019

Scientists identify unique way to treat incurable type of children's brain cancer

An international team of researchers led by Yale University, University of Iowa, and the Translational Genomics Research Institute, an affiliate of City of Hope, has discovered a new pathway that may improve success against an incurable type of children's brain cancer.

23 Aug 2019

Study calls for more aggressive treatments to improve 5-year survival in glioblastoma patients

Despite improvements in median and short-term survival rates for patients with glioblastoma, the most common brain tumor in adults, the percentage of patients achieving five-year survival remains low, according to new Mayo Clinic research.

23 Jun 2019

Study emphasizes need for more aggressive treatments for glioblastoma patients

20 Jun 2019

Artificial nose helps neurosurgeons to identify cancerous tissue during surgery

An artificial nose developed at Tampere University, Finland, helps neurosurgeons to identify cancerous tissue during surgery and enables the more precise excision of tumors.

17 Jun 2019

Researchers propose a new look at the role of ferroptosis in cancer development

Professor of Ghent University and Lead Researcher at the Institute of Biology and Biomedicine of the Lobachevsky University Dmitri Krysko together with scientists from Germany, Professor Marcus Conrad and Professor Jose Pedro Friedmann Angeli recently published an article in the journal Nature Reviews Cancer, one of the highest-rated journals that occupies the 2nd line in the oncology section among 223 journals in this category and has an impact factor of 42.78 according to WoS data.

7 Jun 2019

Study shows both IDH-mutant WHO-defined molecular subgroups could benefit from PCV chemoradiotherapy

A recent, updated predictive analysis of the three WHO-defined molecular subgroups based on isocitrate dehydrogenase 1/2 (IDH) mutation status and 1p/19q co-deletion status represented in the high-risk treatment arms of the NRG Oncology clinical trial NRG-RTOG 9802 indicates that both IDH-mutant sub-groups (IDHmut-noncodel and IDHmut-codel) could benefit from the addition of PCV chemotherapy to radiotherapy treatment.

3 Jun 2019

Computer-assisted diagnostic method aids in early detection of brain tumor growth

A computer-assisted diagnostic procedure helps physicians detect the growth of low-grade brain tumors earlier and at smaller volumes than visual comparison alone, according to a study published May 28 in the open-access journal PLOS Medicine by Hassan Fathallah-Shaykh of the University of Alabama at Birmingham, and colleagues.

From PLOS ONE 29 May 2019

Novel imaging technique uses protein found in scorpion venom to light up brain tumors

A novel imaging technique that uses a synthesized form of scorpion venom to light up brain tumors has shown promise in a clinical trial. The imaging system enables neurosurgeons to better see malignant growths that often are difficult to fully eliminate.

10 May 2019

New drug targeting genetic weakness could become first treatment for childhood brain cancer

A new type of drug that targets a genetic weakness in an untreatable childhood brain cancer could become the first ever treatment designed to target the disease.

9 May 2019

Johns Hopkins researchers uncover role of neurotransmitter in the spread of aggressive cancers

Using human cancer cells, tumor and blood samples from cancer patients, researchers at Johns Hopkins Medicine have uncovered the role of a neurotransmitter in the spread of aggressive cancers. Neurotransmitters are chemical "messengers" that transmit impulses from neurons to other target cells.

25 Apr 2019