Gliomas News and Research

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Researchers introduce CRISPR-mediated genome and cancer shredding as a conceptual paradigm to treat recurrent gliomas

Researchers demonstrated clustered regularly interspersed short palindromic repeats (CRISPR)-mediated elimination of glioblastoma (GBM) cells.

29 Nov 2023

New cortex organoids more accurately represent the human brain

Essential features of the cortex, an important part of the human brain and its development, are more accurately captured in organoids generated by researchers of the Princess Máxima Center for pediatric oncology and the Hubrecht Institute.

28 Nov 2023

Cancer neuroscience: A new frontier in cancer treatment

Cancer cells hijack normal biological processes, allowing them to multiply. For example, tumors spur construction of new blood vessels, building themselves "highways" to supply nutrients.

1 Nov 2023

Collaborative team receives NCI grant to study how to improve immunotherapy for diffuse midline gliomas

Each year, approximately 200 to 300 children in the United States are diagnosed with diffuse midline gliomas (DMG), a tumor that begins in the brain or spinal cord.

19 Oct 2023

New drug could transform how doctors treat grade 2 IDH-mutant gliomas

A top UVA Health cancer expert is highlighting how a new drug could transform how doctors treat a brain tumor that typically strikes younger people.

29 Sep 2023

Study details the key role played by neutrophils in ensuring survival of brain cancers

A Ludwig Cancer Research study has for the first time exhaustively analyzed immune cells known as neutrophils that reside in brain tumors, including gliomas, which develop in the brain itself, and cancers that spread there from the lung, breast and skin.

27 Sep 2023

New form of cellular immunotherapy shows promise against brain tumors in mice

Scientists from the German Cancer Research Center (DKFZ) and the University Medical Center Mannheim (UMM) successfully tested a new form of cellular immunotherapy against brain tumors in mice for the first time.

26 Sep 2023

Peptide vaccine targets H3K27M mutation in midline gliomas, shows promise in early trials

Tumor vaccines can help the body fight cancer. These vaccines alert the patient's immune system to proteins that are carrying cancer-typical alterations.

22 Sep 2023

Unlocking the potential of the ketogenic diet: studies reveal health benefits

Researchers reported on the effects of the ketogenic diet (KD) on various aspects of metabolic and endocrinal health.

20 Sep 2023

New device can help test treatments in patients with gliomas

The shape and size of a grain of rice, the new device can conduct dozens of experiments at once to study the effects of new treatments on some of the hardest-to-treat brain cancers.

7 Sep 2023

New drug could transform treatment of brain tumors in younger people

A top UVA Health cancer expert is highlighting how a new drug could transform how doctors treat a brain tumor that typically strikes younger people.

25 Aug 2023

New drug candidate nearly doubles survival for patients with aggressive childhood brain tumors

For the first time, researchers have found a potential drug candidate that improved outcomes for patients with a type of childhood brain tumor for which there are no effective treatments.

17 Aug 2023

Henry Ford Health researcher wins grant to study circulating cell-free DNA methylation as a tool for glioma detection

Houtan Noushmehr, Ph.D., a researcher at Henry Ford Health, has been awarded a prestigious R01 grant of nearly $2.9M from the National Institutes of Health (NIH) to support a research project titled, "Circulating cell-free DNA methylation as an accurate tool for detection and clinical follow-up of glioma."

27 Jul 2023

AI tool can rapidly decode brain tumor DNA during surgery

Scientists have designed an AI tool that can rapidly decode a brain tumor's DNA to determine its molecular identity during surgery -; critical information that under the current approach can take a few days and up to a few weeks.

7 Jul 2023

Ancient retrovirus may be responsible for aggressive brain cancers

The median length of survival after diagnosis of glioblastoma is 14 months, but some of these brain tumors are more aggressive and resistant to treatment than others, and a new study from Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine suggests reactivation of an ancient retrovirus may be at least partly to blame.

3 Jul 2023

New technology to capture and release cfDNA on nanowire surfaces from urine

A group led by researchers at Nagoya University in Japan has developed a technology to capture and release cell-free DNA (cfDNA) on nanowire surfaces from urine.

3 Jul 2023

New and significant breakthrough made to detect brain tumors

Folate-based radiopharmaceuticals can be used in positron emission tomography (PET) imaging to detect folate receptors in brain tumors.

15 Jun 2023

Revolution in neuroscience: 2D nanomaterials propel advances in brain repair, treatment, and diagnosis

Review discusses the increasing importance of two-dimensional nanomaterials like graphene in neuroscience, highlighting their potential in nerve repair, creating brain-mimicking synaptic devices, and treating neurological disorders. It also considers the challenges and future prospects of these materials in this complex field.

11 Jun 2023

Study suggests possible new treatment option for people with slow-growing but deadly brain tumor

In an international study co-led by UCLA, scientists have shown that a new targeted therapy drug can extend the amount of time people with a subtype of glioma are on treatment without their cancer worsening.

4 Jun 2023

Researchers create an open-source, reproducible analysis platform for pediatric brain tumors

Researchers from Children's Hospital of Philadelphia, the Alex's Lemonade Stand Foundation Childhood Cancer Data Lab, the Children's Brain Tumor Network, the Pacific Pediatric Neuro-Oncology Consortium, and more than 20 additional institutions have partnered to create a first-of-its-kind open-source, reproducible analysis platform for pediatric brain tumors.

31 May 2023