Glucocorticoid News and Research

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Glucocorticoid is a compound that belongs to the family of compounds called corticosteroids (steroids). Glucocorticoids affect metabolism and have anti-inflammatory and immunosuppressive effects. They may be naturally produced (hormones) or synthetic (drugs).

Skin-healing pseudoceramides

Researchers report in the September 2007 issue of the Journal of Lipid Research that they have made synthetic lipids called pseudoceramides that are involved in skin cell growth and could be used in treating skin diseases in which skin cells grow abnormally.

29 Aug 2007

Treating bronchiolitis with steroids doesn't work

For infants with a common and potentially serious viral lower respiratory infection called bronchiolitis, a widely used steroid treatment is not effective.

27 Jul 2007

Dexamethasone steroid treatment shows no benefit for kids with bronchiolitis

DMC Children's Hospital of Michigan has found that a common steroid treatment often prescribed for kids with bronchiolitis has no impact on improving their symptoms or in reducing hospitalization.

26 Jul 2007

Steroid medications don't work in treating lower respiratory infections in children

The use of steroid medication to treat bronchiolitis, a common viral lower respiratory infection in infants , does not prevent hospitalization or improve their respiratory symptoms, according to a study published in the July 26 issue of The New England Journal of Medicine.

26 Jul 2007

Stress and Alzheimer's disease

Subjecting mice to repeated emotional stress, the kind we experience in everyday life, may contribute to the accumulation of neurofibrillary tangles, one of the hallmarks of Alzheimer's disease, report researchers at the Salk Institute for Biological Studies.

17 Jun 2007

New era of treatment for rheumatoid arthritis

Three new drugs for rheumatoid arthritis (RA) have ushered in a new era of treatment for this difficult and debilitating condition.

16 Jun 2007

FDA approves Norditropin for short stature in children with Noonan syndrome

Novo Nordisk has announced that Norditropin (somatropin[rDNA origin] injection) received U.S. Food and Drug Administration (FDA) approval for the treatment of short stature in children with Noonan syndrome.

3 Jun 2007

Why do some people get fat even when they eat relatively little?

What creates that irresistible urge for a bag of potato chips or a hunk of chocolate cake, as opposed to a nice crisp apple? Can food urges be irresistible?

2 May 2007

Genelabs Tech reaches agreement with FDA on special protocol assessment for phase III trial of Prestara in lupus

Genelabs Technologies has announced that it has reached agreement with the U.S. Food and Drug Administration (FDA) on a Special Protocol Assessment (SPA) for a Phase III clinical trial of Prestara (prasterone) for treatment of systemic lupus erythematosus (lupus).

4 Apr 2007

Severe stress can damage a child's brain

According to researchers in the U.S. children who suffer severe stress may also suffer damage to their brains.

5 Mar 2007

Steroid use fails to boost pregnancy rates in infertility treatments

There is no clear benefit from a hormone commonly prescribed to enhance the effectiveness of infertility treatments, according to a new review of studies.

1 Mar 2007

It's a vicious circle - exposure to stress causes anxiety and depression

Experts in the United States say the results of a study with mice suggests that stress in itself may cause anxiety and depression.

18 Apr 2006

Anxiogenic-like effect of chronic corticosterone in the light-dark emergence task in mice

Neuroscientists at Harvard Medical School and its affiliate McLean Hospital have shown that long-term exposure to stress hormone in mice directly results in the anxiety that often comes with depression.

18 Apr 2006

Why anti-obesity cortisol reducing supplements do not work

Researchers at Oregon Health & Science University have revealed that the cortisol/obesity connection, touted by many weight-loss supplement marketers, may be even more tenuous than first thought.

2 Feb 2006

Bisphosphonate use in dermatology patients receiving long-term oral corticosteroid therapy

In a small study from a referral center for dermatology, most patients receiving prolonged oral corticosteroids for chronic skin diseases were not receiving therapies to prevent osteoporosis that may be caused by the drug, according to an article in the January issue of Archives of Dermatology.

16 Jan 2006

Loyola to study for first time IV medication for osteopenia and inflammatory bowel diseases

Researchers at the Osteoporosis and Metabolic Bone Disease Center and the Division of Gastroenterology at Loyola University Health System are studying a once-yearly, 15-minute infusion of an intravenous (IV) medication in patients with osteopenia (low bone mass) and inflammatory bowel diseases (IBD) that, if proven effective, may be considered the standard of treatment.

10 Jan 2006

Women more sensitive to chronic stress than men

"It's generally understood that females respond more strongly to acute (immediate, short-term) stress than males," said Helmer Figueiredo, PhD, of UC's department of psychiatry. "Our research shows that this may also be the case in more clinically relevant chronic-stress conditions."

20 Nov 2005

Sweets may decrease the production of the stress-related hormone glucocorticoid

Researchers from the University of Cincinnati (UC) have found that eating or drinking sweets may decrease the production of the stress-related hormone glucocorticoid--which has been linked to obesity and decreased immune response.

20 Nov 2005

Feeling stressed? reach for the sugar!

Researchers are now saying that reaching for a sugary snack in times of stress may not be such a bad idea after all.

16 Nov 2005

Bright light therapy may aid patients with depressive and bipolar disorders

A report in the November Cell Metabolism reveals powerful effects of light on the adrenal glands, a finding that might explain the broad benefits of bright light therapy for a variety of conditions, including sleep and depressive disorders, according to researchers.

14 Nov 2005