Glycans News and Research

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Researchers report on the sweet side of snake venom toxins

A bite from a lancehead snake can be fatal. Species in the family, found throughout Central and South America, have venom that can disrupt blood clotting and cause hemorrhage, strokes and kidney failure.

4 Jun 2018

Glycan biomarker enhances screening for breast cancer patients

People diagnosed with early-stage breast cancer have a five-year survival rate of more than 93 per cent.

26 Mar 2018

Scientists develop new array to identify biomarkers for wide range of diseases

Scientists have developed a way to identify biomarkers for a wide range of diseases by assessing the antibodies we are making to the complex sugars coating our cells.

12 Feb 2018

GlycoNet researchers to study correlation between sugars and Alzheimer's disease

Two GlycoNet Investigators are using technology to better understand how sugars in the human body are connected to Alzheimer's disease.

12 Feb 2018

Researchers report technical advances in production of HIV vaccines

Research on HIV over the past decade has led to many promising ideas for vaccines to prevent infection by the AIDS virus, but very few candidate vaccines have been tested in clinical trials.

6 Feb 2018

Sugar-attaching enzyme found to be abundant in colon cancer cells

Researchers have identified an enzyme that is absent in healthy colon tissue but abundant in colon cancer cells, according to a report in the Jan. 26 issue of the Journal of Biological Chemistry.

27 Jan 2018

Scientists use computer analysis to complete antibody blueprint

Antibodies defend our bodies against intruders. These molecules consist of proteins with attached sugars. However, the blueprint directing the processing of these sugars on the protein was not well understood until now.

30 Nov 2017

NIH awards $1.5 million grant to support education in Alzheimer's disease at RPI

We know Alzheimer's as a brutal disease that dismantles our loved ones and condemns them to death. But science and engineering researchers look inside the disease to identify early warning signs and develop the imaging techniques to see them, to unravel the biochemical puzzle that creates a toxic clump of misfolded proteins, and to develop and test new drugs and therapies that chip away at cognitive decline.

28 Sep 2017

New discovery by TSRI scientists could speed efforts to develop effective HIV vaccine

Scientists at The Scripps Research Institute have made a discovery that could speed efforts to develop a successful HIV vaccine.

14 Sep 2017

American scientists develop bioorthogonal labeling test to assess sialylated glycans in tumor cells

Glycosylated proteins are often overexpressed in tumor cells and thus could serve as tumor markers, especially those with the interesting molecule sialic acid as their sugar moiety.

28 Jun 2017

TSRI scientists develop novel method to analyze glycan shield on HIV’s glycoprotein

HIV is a master of disguise. The virus uses a shield of sugar molecules, called glycans, to hide from the immune system and block antibodies from attacking it.

28 Mar 2017

Scientists identify genetic clues to chronic kidney disease

Using international genomic studies backed by proof-of-concept cell experiments, researchers have identified two genes that contribute to the chronic kidney disease glomerulonephritis.

16 Mar 2017

New approach could make organometallic catalysis applicable for therapy or diagnostics

A gold catalyst can be delivered to a target organ in a higher organism where it performs a chemical transformation visualized by bioimaging.

17 Feb 2017

Scientists identify sugar molecule that reduces inflammatory response and COPD progression

Using a mouse model, scientists from the RIKEN-Max Planck Joint Research Center for Systems Chemical Biology and a number of other institutes have identified a sugar molecule that reduced the inflammatory response and progress of emphysema, a common component of chronic obstructive pulmonary disease (COPD).

27 Dec 2016

Researcher develops new method to accurately identify elusive molecules

Among the most important molecules in the living world are sugars or carbohydrates, which play a vital role in life processes. Sugars provide the main source of fuel for the body, protect muscles from damage and contribute to the immune response.

21 Dec 2016

NIH-funded scientists work with three ‘omes’ to understand human health

Have you ever collected coins, cards, toy trains, stuffed animals? Did you feel the need to complete the set? If so, then you may be a completist. A completist will go to great lengths to acquire a complete set of something.

17 Dec 2016

Okayama University researchers identify link between plant complex type N-glycans and hay fever

Okayama University researchers identify plants expressing substantial amounts of a nitrogen-linked polysaccharide – plant complex type N-glycans – which is linked to allergic responses in mammals, and may provide useful study models for understanding hay fever.

17 Dec 2016

Researchers develop new way to design glycoclusters for targeted drug delivery

A team led by researchers at the RIKEN Biofunctional Synthetic Chemistry Laboratory in Japan has developed a way to engineer glycan complexes--clusters of sugar chains attached to proteins or lipids--in a way that allows the molecules to be transported preferentially to specific organs of the body, depending on the sugar chains contained in the cluster.

29 Nov 2016

Antibody protection may help control infection caused by TB bacteria

A study led by investigators from the Ragon Institute of MGH, MIT and Harvard finds evidence that antibody protection may help control infection with the bacteria that causes tuberculosis (TB).

4 Oct 2016

Scientists identify new group of molecules that could slow tumour growth in prostate cancer patients

Prostate cancer patients have been offered hope after scientists at Newcastle University, UK, have identified a new group of molecules that could be targeted to slow tumour growth.

28 Jul 2016