Glycoprotein News and Research

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The response of four SARS-CoV-2 spike variants to linoleic acid removal

A recent paper depicted the differential allosteric response of the SARS-CoV-2 spike variants to linoleic acid.

26 Apr 2022

Study reports increased numbers of SARS-CoV-2-reactive T cells in individuals who were HCoV-reactive

T cell responses were measured to three SARS-CoV-2-associated antigens, as well as the endemic coronaviruses HCoV-OC43 and HCoV-NL63.

25 Apr 2022

Study suggests BCG vaccination might confer immunity to SARS-CoV-2

In a recent study posted to the bioRxiv* preprint server, the researchers investigated the impact of Bacillus Calmette-Guérin (BCG) vaccine-induced antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) glycoprotein.

25 Apr 2022

Marine resources could be promising drug candidates against SARS-CoV-2 Omicron

A recent review paper, published in the MDPI’s specialized journal COVID, highlights key features of the Omicron variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – and examines the potential and roadblocks in using renewable marine resources in the fight against the coronavirus disease 2019 (COVID-19).

24 Apr 2022

ST6Gal-I–mediated sialylation of the EGFR modulates cell mechanics and enhances cancer invasion

For more than two decades, University of Alabama at Birmingham researcher Susan Bellis, Ph.D., has studied how the addition of sialic acid to various proteins increases cancer resistance and oncogenicity.

22 Apr 2022

Antibodies that neutralize most sarbecoviruses, including SARS-CoV-2 variants

Researchers isolate three mAbs that broadly neutralized sarbecoviruses and carried out virological and structural studies of these mAbs.

21 Apr 2022

SARS-CoV-2 spike protein disrupts lipid metabolism resulting in liver, heart & kidney damage

A new study describes the impact of SARS-CoV-2 on host lipid metabolism.

21 Apr 2022

Evolution of SARS-CoV-2 variants

Research has demonstrated the evolutionary process and biology of SARS-CoV-2, the causative pathogen of the COVID-19 pandemic.

21 Apr 2022

The brain's reaction to COVID's inflammatory tidal wave

Researchers study neuroinflammation in the cerebrospinal fluid and serum of patients infected with SARS-CoV-2.

18 Apr 2022

Avasimibe inhibits SARS-CoV-2 and boosts T-cell responses

Researchers demonstrate that avasimibe-mediated inhibition of ACAT blocks the entry and fusion of SARS-CoV-2 in different cell types.

18 Apr 2022

Ultralong bovine antibody targets cryptic and conserved epitope on SARS-CoV and SARS-CoV-2

Researchers identified an ultralong bovine antibody that neutralizes SARS-CoV-2 and SARS-CoV.

11 Apr 2022

Neutralization potency against the Omicron variant of naturally expressed MBC-derived IgG antibodies from vaccinated individuals

Researchers have shown how the Omicron variant of the SARS-CoV-2 successfully evaded a large fraction of antibodies derived from memory B cells, giving rise to a reduced, but incomplete immune escape.

8 Apr 2022

Researchers reveal why people with allergic asthma are protected from severe COVID

The vast majority of people infected with the omicron variant of SARS-CoV-2 experience mild cold-like symptoms, moderate flu-like symptoms, or no symptoms at all, but the virus is so transmissible that it still spread deep into lung tissue to cause severe disease and death in thousands of people in the United States in 2022 alone.

7 Apr 2022

Self-assembling SARS-CoV-2 spike protein-directed nanoparticle vaccines

A new preprint study depicted the generation of self-assembling coronavirus disease 2019 (COVID-19) nanoparticle vaccines.

6 Apr 2022

Study highlights immune escape mutations in viral N-terminal domain supersite of SARS-CoV-2 spike variants

Researchers characterized SARS-CoV-2 spike (S) isolates extracted from the samples of two individuals infected with the virus in Peru (ΔN25) and Brazil (ΔN135) in January 2021.

6 Apr 2022

Recombinant fragment of the lectin-binding region of Gal-3BP stimulates the expression of IL-6 in SARS-CoV-2 sensitive cells

A recent study investigated the impact of a recombinant fragment of cellular glycoprotein Gal-3BP on IL-6 expression in acute COVID-19.

5 Apr 2022

Glycoprotein News and Research

The response of four SARS-CoV-2 spike variants to linoleic acid removal

Study reports increased numbers of SARS-CoV-2-reactive T cells in individuals who were HCoV-reactive

Study suggests BCG vaccination might confer immunity to SARS-CoV-2

Marine resources could be promising drug candidates against SARS-CoV-2 Omicron

ST6Gal-I–mediated sialylation of the EGFR modulates cell mechanics and enhances cancer invasion

Antibodies that neutralize most sarbecoviruses, including SARS-CoV-2 variants

SARS-CoV-2 spike protein disrupts lipid metabolism resulting in liver, heart & kidney damage

Evolution of SARS-CoV-2 variants

The brain's reaction to COVID's inflammatory tidal wave

Avasimibe inhibits SARS-CoV-2 and boosts T-cell responses

Ultralong bovine antibody targets cryptic and conserved epitope on SARS-CoV and SARS-CoV-2

Neutralization potency against the Omicron variant of naturally expressed MBC-derived IgG antibodies from vaccinated individuals

Researchers reveal why people with allergic asthma are protected from severe COVID

Self-assembling SARS-CoV-2 spike protein-directed nanoparticle vaccines

Study highlights immune escape mutations in viral N-terminal domain supersite of SARS-CoV-2 spike variants

Recombinant fragment of the lectin-binding region of Gal-3BP stimulates the expression of IL-6 in SARS-CoV-2 sensitive cells

An in-depth analysis of pathogenesis of SARS-CoV-2 and therapeutic options for COVID-19

Study identifies a new class of monoclonal antibodies that neutralize both alpha and beta coronaviruses

Therapeutic antibodies against filoviruses including Ebola and Marburg

How effective are household cleaning agents against SARS-CoV-2?

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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