H1N1 News and Research

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Novel influenza A (H1N1) is a new flu virus of swine origin that was first detected in Mexico and the United States in March and April, 2009. The first novel H1N1 patient in the United States was confirmed by laboratory testing at CDC on April 15, 2009. The second patient was confirmed on April 17, 2009. It was quickly determined that the virus was spreading from person-to-person. On April 22, CDC activated its Emergency Operations Center to better coordinate the public health response. On April 26, 2009, the United States Government declared a public health emergency.

It’s thought that novel influenza A (H1N1) flu spreads in the same way that regular seasonal influenza viruses spread; mainly through the coughs and sneezes of people who are sick with the virus.

Coronavirus is deadlier than flu with seniors at highest risk

The novel coronavirus (CoV) is a new strain of coronavirus that has not been previously identified in humans. The new, or “novel” coronavirus, now called 2019-nCoV, had not previously detected before the outbreak was reported in Wuhan, China in December 2019.

19 Feb 2020

Research reveals new pathogenic mechanism for influenza NS1 protein

Influenza is a deadly virus, with about 290,000 to 650,000 deaths worldwide each year. When pandemics hit, the toll can soar: The Spanish flu of 1918 caused 40 million to 50 million deaths, the Asian flu of 1957 caused 2 million deaths, and the Hong Kong flu of 1968 caused 1 million deaths.

16 Feb 2020

Panicky responses to coronavirus may create many more problems

The new coronavirus is still spreading rapidly, in and out of China. By January 31, barely a month after the new pathogen's appearance on the world stage, already 62 countries had imposed restrictions on the entry of Chinese citizens.

6 Feb 2020

Coronavirus - pandemic or not?

The coronavirus strain called 2019-nCoV has been causing widespread illness in China, with 28,276 affected by the virus and over 565 deaths worldwide, mostly in China. As of now, it is already more deadly than the SARS epidemic that raged between 2002 and 2004.

6 Feb 2020

Coronavirus update: Crucial information about transmission, diagnosis, treatment

The novel coronavirus (2019-nCoV) that has spread from China to more than 25 countries, is more difficult to contain than previously thought. The death toll from the infection soars past 565, with more than 28,256 confirmed cases. Scientists from around the globe are racing to determine the mode of transmission and how the virus spreads at such a rapid pace.

6 Feb 2020

First exposure to influenza virus dictates our lifelong ability to fight flu

Were you born in an H1N1 year or an H3N2 year? The first type of influenza virus we are exposed to in early childhood dictates our ability to fight the flu for the rest of our lives, according to a new study from a team of infectious disease researchers at McMaster University and Université de Montréal.

30 Jan 2020

Coronavirus outbreak now a global health emergency says WHO

The Wuhan coronavirus or 2019-nCoV outbreak continues to spread in mainland China and in more than a dozen countries. In the last 24 hours, 42 had succumbed to the infection, making the death toll hit 213, with 9,692 confirmed cases, prompting the World Health Organization (WHO) to declare the coronavirus outbreak a global health emergency.

30 Jan 2020

New antiviral drug drives treatment resistance in influenza viruses

On January 31, 2019, an 11-year old boy in Japan went to a medical clinic with a fever. The providers there diagnosed him with influenza, a strain called H3N2, and sent him home with a new medication called baloxavir.

25 Nov 2019

New flu drug makes influenza viruses develop resistance

Researchers have discovered a mutation in strains of influenza treated with a drug that makes the virus resistant to treatment.

25 Nov 2019

New textbook on mysterious and deadly cytokine storm syndrome

There's no telling where the call will come from, or when. But Randy Cron, M.D., Ph.D., professor of pediatrics and medicine at UAB, knows to expect them.

11 Nov 2019

Researchers find antibody that may protect against wide range of lethal influenza viruses

A nationwide team of researchers has found an antibody that protects mice against a wide range of potentially lethal influenza viruses, advancing efforts to design of a universal vaccine that could either treat or protect people against all strains of the virus.

25 Oct 2019

Flu antibody could be a key to better treatments for severe flu disease

Researchers have found an antibody that protects mice against a wide range of lethal influenza viruses, according to a study from Washington University School of Medicine in St. Louis, Icahn School of Medicine at Mount Sinai in New York City, and Scripps Research in La Jolla, Calif.

24 Oct 2019

NIAID-supported clinical trial begins at four Vaccine and Treatment Evaluation Units

A clinical trial in which healthy adults will be deliberately infected with influenza virus under carefully controlled conditions is recruiting volunteers at four Vaccine and Treatment Evaluation Units (VTEUs) supported by NIH's National Institute of Allergy and Infectious Diseases.

24 Oct 2019

Mount Sinai researchers receive NIH award to develop universal flu vaccine

Researchers at the Icahn School of Medicine at Mount Sinai have received a contract award of up to $132 million from the National Institute of Allergy and Infectious Diseases of the National Institutes of Health (NIH), as part of a new Collaborative Influenza Vaccine Innovation Centers (CIVICs) program to further develop the universal flu vaccine.

1 Oct 2019

Infectious disease experts explain how to stay healthy during the flu season

About 40 million people contracted the flu last year, with hundreds of thousands hospitalized and 35,400 to 61,000 deaths, including 134 children, according to the Centers for Disease Control and Prevention.

30 Sep 2019

Microbiome loss from antibiotic use affects response to flu vaccine

Every living person has trillions of microbes living in their digestive tract, and more than 400 species of bacteria in the gut, more than the number of cells in the body. The normal gut flora is important to maintain eubiosis, the microbial balance in the body.

9 Sep 2019

Oral antibiotics that kill gut microorganisms can alter immune response to flu vaccines

The normal human gut microbiome is a flourishing community of microorganisms, some of which can affect the human immune system. In a new paper published this week in Cell, researchers found that oral antibiotics, which can kill gut microorganisms, can alter the human immune response to seasonal influenza vaccination.

8 Sep 2019

Ohio State research in flu protection starts at county fairs

For researchers with The Ohio State University College of Veterinary Medicine, the work to identify new flu strains and increase the effectiveness of the flu vaccine begins in an unlikely place – pig barns at state and county fairs nationwide.

12 Aug 2019

Women's greater immune response to flu vaccine declines with age

Women tend to have a greater immune response to a flu vaccination compared to men, but their advantage largely disappears as they age and their estrogen levels decline, suggests a study from researchers at the Johns Hopkins Bloomberg School of Public Health.

17 Jul 2019

$3.1 million NIH funding awarded to develop universal flu vaccine

In the race to create a universal flu vaccine not dependent on predicting strains of flu, the Virginia-Maryland College of Veterinary Medicine's Department of Veterinary Medicine at the University of Maryland College of Agriculture and Natural Resources has been awarded a $3.1 million grant.

1 Jul 2019