H1N1 News and Research

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Novel influenza A (H1N1) is a new flu virus of swine origin that was first detected in Mexico and the United States in March and April, 2009. The first novel H1N1 patient in the United States was confirmed by laboratory testing at CDC on April 15, 2009. The second patient was confirmed on April 17, 2009. It was quickly determined that the virus was spreading from person-to-person. On April 22, CDC activated its Emergency Operations Center to better coordinate the public health response. On April 26, 2009, the United States Government declared a public health emergency.

It’s thought that novel influenza A (H1N1) flu spreads in the same way that regular seasonal influenza viruses spread; mainly through the coughs and sneezes of people who are sick with the virus.

Direct infection and replication of influenza virus in cardiomyocytes is a primary determinant of cardiac pathology associated with severe influenza

Researchers generated a recombinant influenza virus expressing micro ribonucleic acid (miRNAs) expressed in cardiomyocytes to infect mice, which served as a model to study the etiology of influenza-associated cardiac pathology.

13 May 2022

Direct influenza infection of the heart drives cardiac complications, study reveals

Researchers have shown for the first time in mice that heart problems associated with the flu are not caused by raging inflammation in the lungs, as has long been predicted.

11 May 2022

Judge’s ruling on the CDC mask mandate highlights the limits of the agency’s power

The role that the federal government plays in containing future epidemics will hinge on the outcome of an appeal of this week's court ruling that overturned the mask mandate for travelers on airlines, trains, and the nation's mass transit systems.

21 Apr 2022

The preclinical potential of S. miltiorrhiza extracts for the treatment of COVID-19

In a recent study, researchers assessed the anti-COVID-19 efficacy of Salvia miltiorrhiza Bunge.

14 Apr 2022

Study determines hemagglutinin inhibition seroprevalence against swine influenza viruses circulating in Hong Kong and Guangzhou

Researchers performed a quantitative assessment of the age-stratified seroprevalence of hemagglutination inhibition antibodies against five swine influenza viruses circulating in the Guangzhou and Hong Kong cities of China.

13 Apr 2022

Impact of cardiovascular disease in pregnant or postpartum COVID-19 patients

In a recent study posted to the medRxiv* preprint server, researchers reported coronavirus disease 2019 (COVID-19) prognosis worsened by the presence of cardiovascular diseases (CVDs) in pregnant and postpartum women.

11 Apr 2022

Study generates a picture of the myocardial transcriptional landscape of COVID-19

Researchers profiled cardiac tissue transcriptomes of COVID-19 patients.

5 Apr 2022

Groundbreaking collaborative work defines the risk of SARS-CoV-2 variants on immune protection

In a paper in the journal Nature, Los Alamos National Laboratory scientists Bette Korber, Hyejin Yoon, Will Fischer and James Theiler, among nearly 130 authors from institutions around the world, describe their groundbreaking collaborative work, "Defining the risk of SARS-CoV-2 variants on immune protection."

1 Apr 2022

TMPRSS2 inhibitor found to be a novel and effective therapeutic option against pan-variant SARS-CoV-2 infections

Researchers assessed the efficacy of TMPRSS2 against SARS-CoV-2 variants of concern Alpha, Beta, Gamma, and Delta, in mice and human lung cells.

1 Apr 2022

Novel sensor could revolutionize COVID-19 virus testing

A COVID-19 sensor developed at Johns Hopkins University could revolutionize virus testing by adding accuracy and speed to a process that frustrated many during the pandemic.

30 Mar 2022

New compound delivered in a nasal spray effectively treats delta variant infection in mice

Researchers have shown a new compound delivered in a nasal spray is highly effective in preventing and treating COVID-19 caused by the Delta variant in mice.

29 Mar 2022

Evaluating severity of influenza infection in ferrets with COVID-19 history

In a new study, researchers investigated the effect of SARS-CoV-2 exposure on the severity of influenza in ferrets.

28 Mar 2022

Novel mathematical model could predict the evolutionary trend of SARS-CoV-2

Researchers used a novel mathematical model to simulate SARS-CoV-2 dynamics inside the host.

17 Mar 2022

In silico screening of natural ACE2 inhibitors

Researchers identify potential ACE2 inhibitors through a virtual screening protocol.

14 Mar 2022

Immune responses in patients with varying degrees of SARS-CoV-2 infection

In a recent research article published in the journal PLoS ONE, researchers looked at immunological responses in relation to established risk factors for serious illness. This prospective cohort study reports on long-lasting SARS-CoV-2 specific antibody and T-cellular immune responses six months after infection in rt-PCR confirmed cases of different illness severity (community and hospitalized patients).

24 Feb 2022

H1N1 News and Research

Direct infection and replication of influenza virus in cardiomyocytes is a primary determinant of cardiac pathology associated with severe influenza

Direct influenza infection of the heart drives cardiac complications, study reveals

Judge’s ruling on the CDC mask mandate highlights the limits of the agency’s power

The preclinical potential of S. miltiorrhiza extracts for the treatment of COVID-19

Study determines hemagglutinin inhibition seroprevalence against swine influenza viruses circulating in Hong Kong and Guangzhou

Impact of cardiovascular disease in pregnant or postpartum COVID-19 patients

Study generates a picture of the myocardial transcriptional landscape of COVID-19

Groundbreaking collaborative work defines the risk of SARS-CoV-2 variants on immune protection

TMPRSS2 inhibitor found to be a novel and effective therapeutic option against pan-variant SARS-CoV-2 infections

Novel sensor could revolutionize COVID-19 virus testing

New compound delivered in a nasal spray effectively treats delta variant infection in mice

Evaluating severity of influenza infection in ferrets with COVID-19 history

Novel mathematical model could predict the evolutionary trend of SARS-CoV-2

In silico screening of natural ACE2 inhibitors

Immune responses in patients with varying degrees of SARS-CoV-2 infection

Broad-spectrum antiviral activity of picolinic acid against SARS-CoV-2 and Influenza A virus

PCR data sheds light on the dynamics of interspecies pathogen-pathogen interactions

Study investigates if prior SARS-CoV-2 infection increases sensitivity to toxin that induces parkinsonism

Researchers develop influenza virus-like particle-based hybrid vaccine for both influenza and SARS-CoV-2 viruses

Echinacea as a potential force against coronavirus infections

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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