Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

Study findings on novel ST2 cardiac biomarker to be presented at ACC 2011

A novel cardiac biomarker, ST2, will be highlighted in three presentations at the American College of Cardiology in New Orleans this week.

1 Apr 2011

CorMedix reports encouraging interim results from CRMD001 phase II study in Contrast Induced Acute Kidney Injury

CorMedix Inc., a pharmaceutical company focused on developing and commercializing therapeutic products for the prevention and treatment of cardiorenal disease, today announced its interim analysis and clinical update for CRMD001.

1 Apr 2011

FDA grants Nile Fast Track designation for cenderitide post-acute development program

Nile Therapeutics, Inc., a biopharmaceutical company that develops novel therapeutics for heart failure patients, today announced that the U.S. Food and Drug Administration (FDA) has granted Fast Track designation to Nile's post-acute development program for cenderitide, which has the goal of reducing cardiovascular mortality and cardiovascular re-hospitalization in the post-acute period in patients with acute decompensated heart failure.

31 Mar 2011

Regulus obtains exclusive rights from NYU for miR-33a, 33b to treat metabolic diseases

Regulus Therapeutics Inc., a biopharmaceutical company leading the discovery and development of innovative new medicines targeting microRNAs, today announced that it has obtained exclusive rights from New York University for intellectual property covering methods of use in modulating microRNA-33a and microRNA-33b for metabolic diseases such as atherosclerosis and metabolic syndrome.

31 Mar 2011

Abbott launches MitraClip system to treat MR in Australia

Abbott today announced the launch of the company's catheter-based MitraClip system for the treatment of mitral regurgitation in Australia. The MitraClip device, which has received Therapeutic Goods Administration approval, offers a new treatment option for patients suffering from MR, a debilitating heart valve condition.

31 Mar 2011

Drugs' cost deters patients from taking heart medicine

For more than 5 million Americans with heart failure, a critical step to better health is taking the medications they're prescribed. But many patients fail to do so, putting themselves at greater risk of hospitalization and even death. To date, studies have not fully answered why patients fall short when it comes to taking heart medicine. In a study appearing in the April issue of Mayo Clinic Proceedings, Mayo Clinic researchers found the drugs' cost is one of the biggest deterrents.

30 Mar 2011

BIOTRONIK completes patient enrollment in IN-TIME clinical trial to treat HF

BIOTRONIK SE & Co. KG, a leading manufacturer of cardiac devices, announced today that the last chronic heart failure patient was enrolled in IN-TIME at the Schwabing Clinic in Munich, Germany, with principle investigator Professor Stefan Sack, MD.

30 Mar 2011

EC grants marketing authorization for GSK, Valeant's Trobalt to treat epilepsy

GlaxoSmithKline and Valeant Pharmaceuticals International, Inc. announced today that the European Commission has granted marketing authorisation for Trobalt as an adjunctive treatment of partial onset seizures, with or without secondary generalisation in adults aged 18 years and above with epilepsy.

30 Mar 2011

Australian researchers say the search must widen for genes that cause heart defects in babies

Australian scientists have discovered a new group of genes that could be responsible for causing heart defects in children, which affect more than 2000 babies born each year in Australia.

29 Mar 2011

People of all ages and both sexes can have congestive heart failure

Elizabeth Taylor died of congestive heart failure at the age of 79 on March 23. Her death raises awareness of this serious condition that affects an estimated five million Americans.

29 Mar 2011

Interventional radiologists complete RDN human trial in patients with uncontrolled hypertension

Interventional radiologists have completed the first human randomized controlled trial of therapeutic renal denervation or RDN—a procedure that uses a catheter-based probe inserted into the renal artery that emits high-frequency energy to deactivate the nerves near the kidneys that are linked to high blood pressure.

29 Mar 2011

Atypical antipsychotics is a safe mental health medication for nursing home residents

Conventional antipsychotics, antidepressants and benzodiazepines often administered to nursing home residents are no safer than atypical antipsychotics and may carry increased risks, according to an article in CMAJ.

29 Mar 2011

FDA approves Medtronic's Protecta implantable defibrillators

Medtronic, Inc. today announced U.S. Food and Drug Administration approval of the Protecta portfolio of implantable cardioverter-defibrillators and cardiac resynchronization therapy-defibrillators.

29 Mar 2011

Nurse staffing levels, safety net status both factors in patient outcomes

A new study finds that higher nurse staffing levels can lead to better patient outcomes. However, the study also found this to not always be the case at safety net hospitals. Meanwhile, the Connecticut Mirror reports on hospitals' efforts to reduce readmissions. And, in other news, new research has found that patients are less likely to fill prescriptions when doctors specify brand names instead of allowing generic substitutions.

28 Mar 2011

FDA approves Medtronic's Consulta and Syncra pacemaker systems

Medtronic, Inc. today announced that the U.S. Food & Drug Administration has approved its Consulta and Syncra cardiac resynchronization therapy-pacemaker systems.

25 Mar 2011

HDL, BG Medicine to offer galectin-3 testing services for patients with heart failure

Health Diagnostic Laboratory, Inc. and BG Medicine, Inc., announced today an agreement under which HDL, Inc. will offer galectin-3 testing services based on the BG Medicine Galectin-3 Test.

25 Mar 2011

Most clinicians feel systems and procedures for preventing hospital readmissions ineffective

More than nine out of ten clinicians believe that reducing readmissions is an important topic, but few have the resources at hand to tackle it, according to a new study from QuantiaMD®, the leading mobile and online physician community, and the Society of Hospital Medicine (SHM).

24 Mar 2011

First continuous-flow total artificial heart transplant performed at THI

Doctors at the Texas Heart Institute at St. Luke's Episcopal Hospital have successfully implanted the first continuous-flow total artificial heart in a desperately ill patient facing imminent death.

24 Mar 2011

Protein α-myosin could be a promising therapeutic target for myocarditis

Myocardits is an inflammation of the heart muscles that is a major cause of heart failure in young patients. In some cases, the disease is caused by viral infection, but in other patients it is linked to an autoimmune attack on the heart muscle. There are few effective treatment options for myocarditis, in part because the molecular mechanisms that underlie the defect are poorly defined.

24 Mar 2011

Roundup: Calif. lawmakers mull bill to tighten hospital security; abortion measures continue to advance in various states

A California legislative committee gave preliminary approval Tuesday to a bill that would tighten security at hospitals and increase their requirements for reporting violent acts to the state.

24 Mar 2011

Heart Failure News and Research

Further Reading

Study findings on novel ST2 cardiac biomarker to be presented at ACC 2011

CorMedix reports encouraging interim results from CRMD001 phase II study in Contrast Induced Acute Kidney Injury

FDA grants Nile Fast Track designation for cenderitide post-acute development program

Regulus obtains exclusive rights from NYU for miR-33a, 33b to treat metabolic diseases

Abbott launches MitraClip system to treat MR in Australia

Drugs' cost deters patients from taking heart medicine

BIOTRONIK completes patient enrollment in IN-TIME clinical trial to treat HF

EC grants marketing authorization for GSK, Valeant's Trobalt to treat epilepsy

Australian researchers say the search must widen for genes that cause heart defects in babies

People of all ages and both sexes can have congestive heart failure

Interventional radiologists complete RDN human trial in patients with uncontrolled hypertension

Atypical antipsychotics is a safe mental health medication for nursing home residents

FDA approves Medtronic's Protecta implantable defibrillators

Nurse staffing levels, safety net status both factors in patient outcomes

FDA approves Medtronic's Consulta and Syncra pacemaker systems

HDL, BG Medicine to offer galectin-3 testing services for patients with heart failure

Most clinicians feel systems and procedures for preventing hospital readmissions ineffective

First continuous-flow total artificial heart transplant performed at THI

Protein α-myosin could be a promising therapeutic target for myocarditis

Roundup: Calif. lawmakers mull bill to tighten hospital security; abortion measures continue to advance in various states

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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