Heparin News and Research

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Heparin, a highly-sulfated glycosaminoglycan, is widely used as an injectable anticoagulant, and has the highest negative charge density of any known biological molecule. It can also be used to form an inner anticoagulant surface on various experimental and medical devices such as test tubes and renal dialysis machines. Pharmaceutical grade heparin is derived from mucosal tissues of slaughtered meat animals such as porcine (pig) intestine or bovine (cow) lung.

New clinical practice guidelines for managing venous thromboembolism released

Venous thromboembolism, a term referring to blood clots in the veins, is a highly prevalent and far-reaching public health problem that can cause disability and death.

28 Nov 2018

New thrombolytic based on magnetite nanoparticles successfully tested on animals

New anti-thrombosis drug based on magnetite nanoparticles developed at ITMO University was successfully tested on animals. Preclinical studies conducted in terms of the project "PHARMA 2020" showed drug's high efficacy and no side effects.

9 Nov 2018

Aspirin may be effective in preventing blood clots after knee replacement

When it comes to preventing blood clots after a knee replacement, good old aspirin may be just as effective as newer, more expensive drugs.

22 Oct 2018

CSU chemists may help in making extracorporeal life support devices more effective

Smoke inhalation, pneumonia, and combat-related trauma are just a few causes of acute respiratory distress syndrome - a condition where the lungs fill with fluid, and is too often fatal.

24 Sep 2018

Researchers discuss clinical application of bivalirudin in interventional cardiovascular procedures

Anticoagulation is imperative to reduce the incidence of thrombotic complications in patients undergoing percutaneous interventional cardiovascular procedures; however, this is at the expense of increased risk of bleeding.

11 Sep 2018

URI professor develops simpler and quicker method for detecting impurity in heparin

In 2008, a contaminant eluded the quality safeguards in the pharmaceutical industry and infiltrated a large portion of the supply of the popular blood thinner heparin, sickening hundreds and killing about 100 in the U.S.

19 Aug 2018

Novel, stem cell-based model mimics mechanisms of Alzheimer's disease

Scientists in Dresden, Germany, have been successful in mimicking mechanisms of Alzheimer's disease in a novel, stem cell-based model system that reproduces features of human brain tissue.

3 Jul 2018

Oral drug reduces venous thromboembolism recurrence among cancer patients

Research from the University of Warwick indicates that taking a tablet a day can help treat cancer patients of a potentially deadly condition.

11 May 2018

Scientists uncover new insight into earliest stages of mammalian pregnancy

Researchers used 3D imaging with molecular testing to uncover new insight into the earliest stages of mammalian pregnancy--offering clues to unsolved questions in pregnancy.

9 Feb 2018

New clinical practice guideline provides recommendations for use of anticoagulants during heart surgery

The Society of Thoracic Surgeons, the Society of Cardiovascular Anesthesiologists, and the American Society of ExtraCorporeal Technology released a new clinical practice guideline that includes major recommendations for the use of blood thinning medication (anticoagulants) during heart surgery.

22 Jan 2018

New, more easily administered therapies offer benefits for bleeding and clotting disorders

In three studies being presented today during the 59th American Society of Hematology (ASH) Annual Meeting and Exposition in Atlanta, researchers report remarkable benefits from new, more easily administered therapies for bleeding and clotting disorders.

11 Dec 2017

New strategy offers therapeutic alternative to prevent excessive clotting in kidney disease patients

Researchers at Boston University School of Medicine have discovered a potential treatment target to prevent chronic kidney disease patients from developing blood clots without causing bleeding complications - an unwanted and perplexing side effect.

29 Nov 2017

NIH awards $1.5 million grant to support education in Alzheimer's disease at RPI

We know Alzheimer's as a brutal disease that dismantles our loved ones and condemns them to death. But science and engineering researchers look inside the disease to identify early warning signs and develop the imaging techniques to see them, to unravel the biochemical puzzle that creates a toxic clump of misfolded proteins, and to develop and test new drugs and therapies that chip away at cognitive decline.

28 Sep 2017

New pig model for stroke could accelerate drug discovery process

It is well-known in the medical field that the pig brain shares certain physiological and anatomical similarities with the human brain. So similar are the two that researchers at the University of Georgia's Regenerative Bioscience Center have developed the first U.S. pig model for stroke treatments, which will provide essential preclinical data and speed the drug discovery process.

26 Sep 2017

Modified blood thinner may be first promising method to prevent repercussions after TBI

A chemically modified version of the common blood thinner heparin may be the first promising method of preventing the harmful cascade of destruction to brain tissue that commonly follows traumatic brain injury (TBI), according to new research findings.

13 Sep 2017

Heparin promotes food intake and body weight gain in animal models

Heparin is a medication widely used to prevent blood clotting; it is named after and mimics the naturally occurring anticoagulant in the body.

6 Sep 2017

Online education enhances administration of blood clot-preventing medications

Results of a yearlong study funded by the Patient-Centered Outcomes Research Institute (PCORI) with more than 900 nurses at The Johns Hopkins Hospital suggest that well-designed online education can decrease the rate of nonadministration of prescribed and necessary doses of blood thinners to prevent potentially lethal blood clots in hospitalized patients.

16 Aug 2017

Heparin News and Research

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