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Elevated pressure in the bile canaliculi alters structure of the liver tissue

The liver produces bile, which the intestine uses for digestion. For the transport of bile, the liver relies on a network of microscopic tubings, known as bile canaliculi, formed by liver cells called hepatocytes.

7 Sep 2023

Study identifies racial and ethnic differences and emerging trends for deadly liver cancer

A new analysis of liver cancer has identified racial and ethnic differences and emerging trends for this highly fatal disease.

5 Sep 2023

Wild boars and Hepatitis E: Whats the zoonotic risk?

The prevalence of the Hepatitis E virus (HEV) in the Portuguese wild boar population.

4 Sep 2023

RSV can be life-threatening for some people: Study

Every year, respiratory syncytial viruses (RSV) cause countless respiratory infections worldwide. For infants, young children and people with preexisting conditions, the virus can be life-threatening.

4 Sep 2023

Amgen to discuss application for LUMAKRAS® (sotorasib) for the treatment of KRAS G12C-positive NSCLC at FDA advisory committee meeting

Amgen today announced the U.S. Food and Drug Administration (FDA) Oncologic Drugs Advisory Committee (ODAC) will review data supporting the supplemental New Drug Application (sNDA) for the full approval of LUMAKRAS® (sotorasib) for adults with previously treated locally advanced or metastatic KRAS G12C-mutated non-small cell lung cancer (NSCLC) at a meeting on Oct. 5, 2023.

From AMGEN 1 Sep 2023

Study finds potential HIV cure using existing cancer drug

An existing blood cancer drug has shown promise in killing 'silent' HIV cells and delaying reinfections – a significant pre-clinical discovery that could lead to a future cure for the disease.

30 Aug 2023

Keck School of Medicine researchers receive $12 million grant to study early liver transplantation

Alcohol-associated liver disease accounts for 50% of liver-related deaths, and its rates are rising worldwide.

24 Aug 2023

Study explores the effects of different diets on plasma proteins

Researchers investigated the relationship between diet and the proteome.

22 Aug 2023

Strengthening prison reentry programs can help reduce opioid overdose deaths in the U.S.

With opioid overdose deaths surging in the United States, many communities are in desperate need of solutions to bring down the body count. Among the most promising is strengthening prison reentry programs for highest-risk users, a Rutgers-led study has found.

21 Aug 2023

Pig kidney xenotransplantation continues to function well after 32 days

Surgeons at NYU Langone Health have transplanted a genetically engineered pig kidney that continues to function well after 32 days in a man declared dead by neurologic criteria and maintained with a beating heart on ventilator support.

16 Aug 2023

Newly identified helicase might hold the key to a novel family of anti-COVID-19 drugs

Researchers used a multidisciplinary approach to investigate a nonstructural protein essential in SARS-CoV-2 replication.

10 Aug 2023

Yale researchers create "humanized" liver in living mice to study chronic liver diseases

Yale researchers have created a functional "humanized" liver in living mice that will help scientists find human-specific mechanisms for regulating cholesterol levels and potentially for treating chronic liver diseases afflicting tens of millions of people in the United States.

9 Aug 2023

Sugar-sweetened beverages linked to increased risk of liver cancer and chronic liver disease mortality

Approximately 65% of adults in the United States consume sugar sweetened beverages daily. Chronic liver disease is a major cause of morbidity and mortality worldwide and can result in liver cancer and liver disease-related mortality.

8 Aug 2023

Identification of plasma proteins associated with ovarian cancer risk

Researchers performed proteomic Mendelian randomization as well as co-localization analyses to identify drug targets for ovarian cancer.

8 Aug 2023

Hepatitis C treatment initiation found to be low among Medicaid recipients

While there are highly effective treatments for the hepatitis C virus (HCV), only 1 in 5 Medicaid enrollees diagnosed with HCV started treatment, according to a retrospective study led by researchers at Weill Cornell Medicine and Cornell University's Ithaca campus.

8 Aug 2023

Researchers uncover genetic machinery responsible for EBV-induced B cell growth transformation

B cells or B lymphocytes are an important part of the body's immune system. When healthy B cells are infected with the Epstein-Barr virus (EBV), they undergo growth transformation, a process that immortalizes B cells, leading to their uncontrolled proliferation.

7 Aug 2023

Penn State researchers develop new method for creating cyclopropanes

Chemical structures called cyclopropanes can increase the potency and fine-tune the properties of many drugs, but traditional methods to create this structure only work with certain molecules and require highly reactive-;potentially explosive-;ingredients. Now, a team of researchers from Penn State has identified and demonstrated a safe, efficient and practical way to create cyclopropanes on a wide variety of molecules using a previously undescribed chemical process.

4 Aug 2023

CDC report highlights the gaps in care of hepatitis C treatment

The prevalence of hepatitis C virus clearance was only 34% overall and even lower in individuals between 20 and 39 years of age.

3 Aug 2023

Hepatitis C cure still linked to higher mortality rates

Individuals who have been cured of hepatitis C infection still face a substantially greater risk of death compared with the general population - between 3 and 14 times higher depending on liver disease stage, finds the largest study of its kind published by The BMJ today.

2 Aug 2023

What are the mediators linking cardiometabolic risk factors and severe COVID-19?

Researchers performed a genome-wide association study to explore whether biomarker levels are causally related to COVID-19 hospitalization.

2 Aug 2023

Hepatitis News and Research

Elevated pressure in the bile canaliculi alters structure of the liver tissue

Study identifies racial and ethnic differences and emerging trends for deadly liver cancer

Wild boars and Hepatitis E: Whats the zoonotic risk?

RSV can be life-threatening for some people: Study

Amgen to discuss application for LUMAKRAS® (sotorasib) for the treatment of KRAS G12C-positive NSCLC at FDA advisory committee meeting

Study finds potential HIV cure using existing cancer drug

Keck School of Medicine researchers receive $12 million grant to study early liver transplantation

Study explores the effects of different diets on plasma proteins

Strengthening prison reentry programs can help reduce opioid overdose deaths in the U.S.

Pig kidney xenotransplantation continues to function well after 32 days

Newly identified helicase might hold the key to a novel family of anti-COVID-19 drugs

Yale researchers create "humanized" liver in living mice to study chronic liver diseases

Sugar-sweetened beverages linked to increased risk of liver cancer and chronic liver disease mortality

Identification of plasma proteins associated with ovarian cancer risk

Hepatitis C treatment initiation found to be low among Medicaid recipients

Researchers uncover genetic machinery responsible for EBV-induced B cell growth transformation

Penn State researchers develop new method for creating cyclopropanes

CDC report highlights the gaps in care of hepatitis C treatment

Hepatitis C cure still linked to higher mortality rates

What are the mediators linking cardiometabolic risk factors and severe COVID-19?

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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